{"id":7901,"date":"2020-07-01T19:49:25","date_gmt":"2020-07-02T02:49:25","guid":{"rendered":"https:\/\/depts.washington.edu\/pandemicalliance\/?p=7901"},"modified":"2021-03-29T19:50:19","modified_gmt":"2021-03-30T02:50:19","slug":"heat-inactivation-of-serum-interferes-with-the-immunoanalysis-of-antibodies-to-sars%e2%80%90cov%e2%80%902","status":"publish","type":"post","link":"https:\/\/depts.washington.edu\/pandemicalliance\/2020\/07\/01\/heat-inactivation-of-serum-interferes-with-the-immunoanalysis-of-antibodies-to-sars%e2%80%90cov%e2%80%902\/","title":{"rendered":"Heat Inactivation of Serum Interferes with the\u00a0Immunoanalysis\u00a0of Antibodies to SARS\u2010CoV\u20102"},"content":{"rendered":"<ul>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"34\" data-aria-posinset=\"2019\" data-aria-level=\"1\"><span data-contrast=\"auto\">SARS-CoV-2 antibody levels decreased significantly after heat inactivation of serum at 56 C, which is a proposed method of reducing exposure risk for laboratory personnel. The IgM levels decreased in all 34 serum samples by mean of 54%. IgG levels decreased in 22 of 34 samples (65%) by a mean of 50%.<\/span><span data-ccp-props=\"{&quot;134233279&quot;:true}\">\u00a0<\/span><\/li>\n<\/ul>\n<p><i><span data-contrast=\"none\">Hu et al. (June 28, 2020). Heat Inactivation of Serum Interferes with the\u00a0Immunoanalysis\u00a0of Antibodies to SARS\u2010CoV\u20102. Journal of Clinical Laboratory Analysis.<\/span><\/i><span data-contrast=\"auto\">\u00a0<\/span><a href=\"https:\/\/doi.org\/10.1002\/jcla.23411\"><span data-contrast=\"none\">https:\/\/doi.org\/10.1002\/jcla.23411<\/span><\/a><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;335559685&quot;:720}\">\u00a0<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"<p>SARS-CoV-2 antibody levels decreased significantly after heat inactivation of serum at 56 C, which is a proposed method of reducing exposure risk for laboratory personnel. The IgM levels decreased in all 34 serum samples by mean of 54%. IgG levels decreased in 22 of 34 samples (65%) by a mean of 50%.\u00a0 Hu et al&#8230;.<\/p>\n<div><a class=\"more\" href=\"https:\/\/depts.washington.edu\/pandemicalliance\/2020\/07\/01\/heat-inactivation-of-serum-interferes-with-the-immunoanalysis-of-antibodies-to-sars%e2%80%90cov%e2%80%902\/\">Read more<\/a><\/div>\n","protected":false},"author":8,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":"","_links_to":"","_links_to_target":""},"categories":[6],"tags":[],"topic":[19],"class_list":["post-7901","post","type-post","status-publish","format-standard","hentry","category-article-summary","topic-testing-and-treatment"],"_links":{"self":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/7901","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/users\/8"}],"replies":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/comments?post=7901"}],"version-history":[{"count":1,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/7901\/revisions"}],"predecessor-version":[{"id":7902,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/7901\/revisions\/7902"}],"wp:attachment":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/media?parent=7901"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/categories?post=7901"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/tags?post=7901"},{"taxonomy":"topic","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/topic?post=7901"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}