{"id":7974,"date":"2021-03-29T17:22:04","date_gmt":"2021-03-30T00:22:04","guid":{"rendered":"https:\/\/depts.washington.edu\/pandemicalliance\/?p=7974"},"modified":"2021-03-30T17:22:56","modified_gmt":"2021-03-31T00:22:56","slug":"quantitative-sars-cov-2-anti-spike-responses-to-pfizer-biontech-and-oxford-astrazeneca-vaccines-by-previous-infection-status","status":"publish","type":"post","link":"https:\/\/depts.washington.edu\/pandemicalliance\/2021\/03\/29\/quantitative-sars-cov-2-anti-spike-responses-to-pfizer-biontech-and-oxford-astrazeneca-vaccines-by-previous-infection-status\/","title":{"rendered":"Quantitative SARS-CoV-2 Anti-Spike Responses to Pfizer-BioNTech and Oxford-AstraZeneca Vaccines by Previous Infection Status"},"content":{"rendered":"<ul>\n<li style=\"font-weight: 400\"><i><span style=\"font-weight: 400\">[Pre-print, not peer-reviewed]<\/span><\/i><span style=\"font-weight: 400\"> Vaccination with either the Pfizer-BioNTech or Oxford-AstraZeneca vaccines led to detectable anti-spike antibodies in nearly all participants in a study of adult healthcare workers (HCWs) in the UK. <\/span><span style=\"font-weight: 400\">3570\/3610 (98.9%) HCWs were seropositive &gt;14 days post-first vaccination and prior to second vaccination, 2706\/2720 (99.5%) after Pfizer-BioNTech and 864\/890 (97.1%) following Oxford-AstraZeneca vaccines. HCWs who had previously been infected or were younger were more likely to test seropositive post-first vaccination, with no evidence of differences by sex or ethnicity, and all HCWs tested &gt;14 days after the second vaccine were seropositive. Antibody responses post-second vaccination were similar to those after prior infection and one vaccine dose.<\/span><\/li>\n<\/ul>\n<p><i><span style=\"font-weight: 400\">Eyre et al.\u00a0(Mar 26, 2021). Quantitative SARS-CoV-2 Anti-Spike Responses to Pfizer-BioNTech and Oxford-AstraZeneca Vaccines by Previous Infection Status. Pre-print downloaded Mar 29 from <\/span><\/i><a href=\"https:\/\/doi.org\/10.1101\/2021.03.21.21254061\"><span style=\"font-weight: 400\">https:\/\/doi.org\/10.1101\/2021.03.21.21254061<\/span><\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>[Pre-print, not peer-reviewed] Vaccination with either the Pfizer-BioNTech or Oxford-AstraZeneca vaccines led to detectable anti-spike antibodies in nearly all participants in a study of adult healthcare workers (HCWs) in the UK. 3570\/3610 (98.9%) HCWs were seropositive &gt;14 days post-first vaccination and prior to second vaccination, 2706\/2720 (99.5%) after Pfizer-BioNTech and 864\/890 (97.1%) following Oxford-AstraZeneca vaccines&#8230;.<\/p>\n<div><a class=\"more\" href=\"https:\/\/depts.washington.edu\/pandemicalliance\/2021\/03\/29\/quantitative-sars-cov-2-anti-spike-responses-to-pfizer-biontech-and-oxford-astrazeneca-vaccines-by-previous-infection-status\/\">Read more<\/a><\/div>\n","protected":false},"author":8,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":"","_links_to":"","_links_to_target":""},"categories":[6],"tags":[67,142],"topic":[31],"class_list":["post-7974","post","type-post","status-publish","format-standard","hentry","category-article-summary","tag-antibodies","tag-vaccine","topic-vaccines-and-immunity"],"_links":{"self":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/7974","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/users\/8"}],"replies":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/comments?post=7974"}],"version-history":[{"count":1,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/7974\/revisions"}],"predecessor-version":[{"id":7975,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/7974\/revisions\/7975"}],"wp:attachment":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/media?parent=7974"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/categories?post=7974"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/tags?post=7974"},{"taxonomy":"topic","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/topic?post=7974"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}