{"id":8007,"date":"2020-07-07T17:44:02","date_gmt":"2020-07-08T00:44:02","guid":{"rendered":"https:\/\/depts.washington.edu\/pandemicalliance\/?p=8007"},"modified":"2021-03-30T17:44:44","modified_gmt":"2021-03-31T00:44:44","slug":"tocilizumab-in-patients-with-severe-covid%e2%80%9019-a-single%e2%80%90center-observational-analysis","status":"publish","type":"post","link":"https:\/\/depts.washington.edu\/pandemicalliance\/2020\/07\/07\/tocilizumab-in-patients-with-severe-covid%e2%80%9019-a-single%e2%80%90center-observational-analysis\/","title":{"rendered":"Tocilizumab in patients with severe COVID\u201019: A single\u2010center observational analysis"},"content":{"rendered":"<ul>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"8\" data-aria-posinset=\"2\" data-aria-level=\"1\"><span data-contrast=\"auto\">Knorr et al.\u00a0<\/span><span data-contrast=\"auto\">f<\/span><span data-contrast=\"auto\">ind\u00a0<\/span><span data-contrast=\"auto\">limited clinical improvement in 66 patients<\/span><span data-contrast=\"auto\">\u00a0with severe COVID\u201019<\/span><span data-contrast=\"auto\">\u00a0who received tocilizumab. Within 14 days of treatment, 29% of patients had clinical improvement, 20% had minimal or no improvement, 17% worsened, 27% died, and 7% were transferred to an outside hospital. Ultimately, 42% of all patients\u00a0<\/span><span data-contrast=\"auto\">who\u00a0<\/span><span data-contrast=\"auto\">received tocilizumab\u00a0<\/span><span data-contrast=\"auto\">died<\/span><span data-contrast=\"auto\">\u00a0<\/span><span data-contrast=\"auto\">and 49% were discharged.<\/span><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559685&quot;:360,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li>\n<\/ul>\n<p><i><span data-contrast=\"none\">Knorr et al. (June 17, 2020). Tocilizumab in patients with severe COVID\u201019: A single\u2010center observational analysis. Journal of Medical Virology.\u00a0<\/span><\/i><a href=\"https:\/\/doi.org\/10.1002\/jmv.26191\"><span data-contrast=\"none\">https:\/\/doi.org\/10.1002\/jmv.26191<\/span><\/a><span data-ccp-props=\"{&quot;201341983&quot;:0,&quot;335559685&quot;:720,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Knorr et al.\u00a0find\u00a0limited clinical improvement in 66 patients\u00a0with severe COVID\u201019\u00a0who received tocilizumab. Within 14 days of treatment, 29% of patients had clinical improvement, 20% had minimal or no improvement, 17% worsened, 27% died, and 7% were transferred to an outside hospital. Ultimately, 42% of all patients\u00a0who\u00a0received tocilizumab\u00a0died\u00a0and 49% were discharged.\u00a0 Knorr et al. (June 17,&#8230;<\/p>\n<div><a class=\"more\" href=\"https:\/\/depts.washington.edu\/pandemicalliance\/2020\/07\/07\/tocilizumab-in-patients-with-severe-covid%e2%80%9019-a-single%e2%80%90center-observational-analysis\/\">Read more<\/a><\/div>\n","protected":false},"author":8,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":"","_links_to":"","_links_to_target":""},"categories":[6],"tags":[],"topic":[19],"class_list":["post-8007","post","type-post","status-publish","format-standard","hentry","category-article-summary","topic-testing-and-treatment"],"_links":{"self":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/8007","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/users\/8"}],"replies":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/comments?post=8007"}],"version-history":[{"count":1,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/8007\/revisions"}],"predecessor-version":[{"id":8008,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/8007\/revisions\/8008"}],"wp:attachment":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/media?parent=8007"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/categories?post=8007"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/tags?post=8007"},{"taxonomy":"topic","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/topic?post=8007"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}