{"id":8167,"date":"2021-03-30T10:00:45","date_gmt":"2021-03-30T17:00:45","guid":{"rendered":"https:\/\/depts.washington.edu\/pandemicalliance\/?p=8167"},"modified":"2021-03-31T10:01:58","modified_gmt":"2021-03-31T17:01:58","slug":"verified-infections-with-endemic-common-cold-coronaviruses-do-not-entail-significant-protection-against-sars-cov-2","status":"publish","type":"post","link":"https:\/\/depts.washington.edu\/pandemicalliance\/2021\/03\/30\/verified-infections-with-endemic-common-cold-coronaviruses-do-not-entail-significant-protection-against-sars-cov-2\/","title":{"rendered":"Verified infections with endemic common cold coronaviruses do not entail significant protection against SARS-CoV-2"},"content":{"rendered":"<ul>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">A previous confirmed seasonal coronavirus infection does not appear to provide protection against subsequent infection with SARS-CoV-2, according to analysis of a large database of respiratory specimens in Sweden. The analysis is based on a database of &gt;75,000 respiratory specimens collected from 2013-2020 and linked to 10,000 samples collected during the pandemic (February-November 2020). There was substantial overlap in the patient population between the two cohorts, allowing the authors to determine whether a previous PCR confirmed coronavirus infection was associated with a reduced likelihood of a subsequent SARS-CoV-2 infection. They found no relationship between a prior coronavirus infection and subsequent SARS-CoV-2 infection when compared to previous infection with the immunologically unrelated rhinovirus, including when restricting their analysis to either alpha or beta-coronaviruses. Additionally, they found no relationship with either viral load or hospitalization (although only 20 participants were hospitalized with COVID-19).\u00a0<\/span><\/li>\n<\/ul>\n<p><i><span style=\"font-weight: 400\">Ringlander et al. (Mar 29, 2021). Verified infections with endemic common cold coronaviruses do not entail significant protection against SARS-CoV-2. Journal of Infectious Disease. <\/span><\/i><a href=\"https:\/\/doi.org\/10.1093\/infdis\/jiab089\"><em><span style=\"font-weight: 400\">https:\/\/doi.org\/10.1093\/infdis\/jiab089<\/span><\/em><\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>A previous confirmed seasonal coronavirus infection does not appear to provide protection against subsequent infection with SARS-CoV-2, according to analysis of a large database of respiratory specimens in Sweden. The analysis is based on a database of &gt;75,000 respiratory specimens collected from 2013-2020 and linked to 10,000 samples collected during the pandemic (February-November 2020). There&#8230;<\/p>\n<div><a class=\"more\" href=\"https:\/\/depts.washington.edu\/pandemicalliance\/2021\/03\/30\/verified-infections-with-endemic-common-cold-coronaviruses-do-not-entail-significant-protection-against-sars-cov-2\/\">Read more<\/a><\/div>\n","protected":false},"author":8,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":"","_links_to":"","_links_to_target":""},"categories":[6],"tags":[32],"topic":[31],"class_list":["post-8167","post","type-post","status-publish","format-standard","hentry","category-article-summary","tag-immunity","topic-vaccines-and-immunity"],"_links":{"self":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/8167","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/users\/8"}],"replies":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/comments?post=8167"}],"version-history":[{"count":1,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/8167\/revisions"}],"predecessor-version":[{"id":8168,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/8167\/revisions\/8168"}],"wp:attachment":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/media?parent=8167"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/categories?post=8167"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/tags?post=8167"},{"taxonomy":"topic","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/topic?post=8167"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}