{"id":8186,"date":"2021-03-31T09:47:33","date_gmt":"2021-03-31T16:47:33","guid":{"rendered":"https:\/\/depts.washington.edu\/pandemicalliance\/?p=8186"},"modified":"2021-04-01T09:48:23","modified_gmt":"2021-04-01T16:48:23","slug":"initial-report-of-decreased-sars-cov-2-viral-load-after-inoculation-with-the-bnt162b2-vaccine","status":"publish","type":"post","link":"https:\/\/depts.washington.edu\/pandemicalliance\/2021\/03\/31\/initial-report-of-decreased-sars-cov-2-viral-load-after-inoculation-with-the-bnt162b2-vaccine\/","title":{"rendered":"Initial Report of Decreased SARS-CoV-2 Viral Load after Inoculation with the BNT162b2 Vaccine"},"content":{"rendered":"<ul>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">In a real-world analysis of data from individuals in Israel who tested positive for SARS-CoV-2 after receiving the first dose of the Pfizer-BioNTech vaccination (n=4,938), viral load was substantially lower (2.8 to 4.5-fold lower) for infections occurring 12-37 days after the first dose compared to individuals who had not been vaccinated. Cycle of threshold (Ct) values for the\u00a0<\/span><i><span style=\"font-weight: 400\">E<\/span><\/i><span style=\"font-weight: 400\">\u00a0gene,\u00a0<\/span><i><span style=\"font-weight: 400\">RdRp<\/span><\/i><span style=\"font-weight: 400\">\u00a0gene,\u00a0<\/span><i><span style=\"font-weight: 400\">N<\/span><\/i><span style=\"font-weight: 400\">\u00a0gene and the internal control were determined for each positive test. The authors suggest that reduced viral loads may affect viral shedding, contagiousness, and disease severity.<\/span><\/li>\n<\/ul>\n<p><i><span style=\"font-weight: 400\">Levine-Tiefenbrun et al. (Mar 29, 2021). Initial Report of Decreased SARS-CoV-2 Viral Load after Inoculation with the BNT162b2 Vaccine. Nature Medicine. <\/span><\/i><a href=\"https:\/\/doi.org\/10.1038\/s41591-021-01316-7\"><span style=\"font-weight: 400\">https:\/\/doi.org\/10.1038\/s41591-021-01316-7<\/span><\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>In a real-world analysis of data from individuals in Israel who tested positive for SARS-CoV-2 after receiving the first dose of the Pfizer-BioNTech vaccination (n=4,938), viral load was substantially lower (2.8 to 4.5-fold lower) for infections occurring 12-37 days after the first dose compared to individuals who had not been vaccinated. Cycle of threshold (Ct)&#8230;<\/p>\n<div><a class=\"more\" href=\"https:\/\/depts.washington.edu\/pandemicalliance\/2021\/03\/31\/initial-report-of-decreased-sars-cov-2-viral-load-after-inoculation-with-the-bnt162b2-vaccine\/\">Read more<\/a><\/div>\n","protected":false},"author":8,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":"","_links_to":"","_links_to_target":""},"categories":[6],"tags":[147,33],"topic":[31],"class_list":["post-8186","post","type-post","status-publish","format-standard","hentry","category-article-summary","tag-vaccination","tag-vaccines","topic-vaccines-and-immunity"],"_links":{"self":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/8186","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/users\/8"}],"replies":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/comments?post=8186"}],"version-history":[{"count":1,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/8186\/revisions"}],"predecessor-version":[{"id":8187,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/8186\/revisions\/8187"}],"wp:attachment":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/media?parent=8186"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/categories?post=8186"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/tags?post=8186"},{"taxonomy":"topic","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/topic?post=8186"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}