{"id":8219,"date":"2020-07-14T11:12:18","date_gmt":"2020-07-14T18:12:18","guid":{"rendered":"https:\/\/depts.washington.edu\/pandemicalliance\/?p=8219"},"modified":"2021-04-01T11:13:02","modified_gmt":"2021-04-01T18:13:02","slug":"liver-injury-in-critically-ill-and-non-critically-ill-covid-19-patients-a-multicenter-retrospective-observational-study","status":"publish","type":"post","link":"https:\/\/depts.washington.edu\/pandemicalliance\/2020\/07\/14\/liver-injury-in-critically-ill-and-non-critically-ill-covid-19-patients-a-multicenter-retrospective-observational-study\/","title":{"rendered":"Liver Injury in Critically Ill and Non-Critically Ill COVID-19 Patients: A Multicenter, Retrospective, Observational Study"},"content":{"rendered":"<ul>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"34\" data-aria-posinset=\"2019\" data-aria-level=\"1\"><span data-contrast=\"auto\">Results from a retrospective observational study (n=131) across three hospitals in Zhejiang, China suggest that critically ill COVID-19 patients suffered earlier occurrence, greater injury severity, and slower recovery from liver injury compared to non-critically ill patients. The combination treatment of lopinavir\/ritonavir and\u00a0arbidol\u00a0<\/span><span data-contrast=\"auto\">was<\/span><span data-contrast=\"auto\">\u00a0associated with higher\u00a0<\/span><span data-contrast=\"auto\">risk or liver injury among non-critically ill patie<\/span><span data-contrast=\"auto\">n<\/span><span data-contrast=\"auto\">ts (OR=3.58, 95%CI: 1.44-9.52).<\/span><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li>\n<\/ul>\n<p><i><span data-contrast=\"none\">Jiang et al. (June 23, 2020). Liver Injury in Critically Ill and Non-Critically Ill COVID-19 Patients: A Multicenter, Retrospective, Observational Study. Frontiers in Medicine.\u00a0<\/span><\/i><a href=\"https:\/\/doi.org\/10.3389\/fmed.2020.00347\"><span data-contrast=\"none\">https:\/\/doi.org\/10.3389\/fmed.2020.00347<\/span><\/a><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559685&quot;:720,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Results from a retrospective observational study (n=131) across three hospitals in Zhejiang, China suggest that critically ill COVID-19 patients suffered earlier occurrence, greater injury severity, and slower recovery from liver injury compared to non-critically ill patients. The combination treatment of lopinavir\/ritonavir and\u00a0arbidol\u00a0was\u00a0associated with higher\u00a0risk or liver injury among non-critically ill patients (OR=3.58, 95%CI: 1.44-9.52).\u00a0 Jiang&#8230;<\/p>\n<div><a class=\"more\" href=\"https:\/\/depts.washington.edu\/pandemicalliance\/2020\/07\/14\/liver-injury-in-critically-ill-and-non-critically-ill-covid-19-patients-a-multicenter-retrospective-observational-study\/\">Read more<\/a><\/div>\n","protected":false},"author":8,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":"","_links_to":"","_links_to_target":""},"categories":[6],"tags":[],"topic":[20],"class_list":["post-8219","post","type-post","status-publish","format-standard","hentry","category-article-summary","topic-clinical-characteristics-and-health-care-setting"],"_links":{"self":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/8219","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/users\/8"}],"replies":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/comments?post=8219"}],"version-history":[{"count":1,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/8219\/revisions"}],"predecessor-version":[{"id":8220,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/8219\/revisions\/8220"}],"wp:attachment":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/media?parent=8219"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/categories?post=8219"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/tags?post=8219"},{"taxonomy":"topic","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/topic?post=8219"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}