{"id":8239,"date":"2020-07-15T11:25:17","date_gmt":"2020-07-15T18:25:17","guid":{"rendered":"https:\/\/depts.washington.edu\/pandemicalliance\/?p=8239"},"modified":"2021-04-01T11:26:02","modified_gmt":"2021-04-01T18:26:02","slug":"at-what-times-during-infection-is-sars-cov-2-detectable-and-no-longer-detectable-using-rt-pcr-based-tests-a-systematic-review-of-individual-participant-data","status":"publish","type":"post","link":"https:\/\/depts.washington.edu\/pandemicalliance\/2020\/07\/15\/at-what-times-during-infection-is-sars-cov-2-detectable-and-no-longer-detectable-using-rt-pcr-based-tests-a-systematic-review-of-individual-participant-data\/","title":{"rendered":"At What Times during Infection Is SARS-CoV-2 Detectable and No Longer Detectable Using RT-PCR Based Tests A Systematic Review of Individual Participant Data"},"content":{"rendered":"<ul>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"34\" data-aria-posinset=\"2019\" data-aria-level=\"1\"><i><span data-contrast=\"none\">[Preprint, not peer-reviewed]\u00a0<\/span><\/i><span data-contrast=\"auto\">A systematic review\u00a0<\/span><span data-contrast=\"auto\">(<\/span><span data-contrast=\"auto\">32 studies\u00a0<\/span><span data-contrast=\"auto\">with<\/span><span data-contrast=\"auto\">\u00a0<\/span><span data-contrast=\"auto\">1,023 SARS-CoV-2 infected patients<\/span><span data-contrast=\"auto\">)<\/span><span data-contrast=\"auto\">\u00a0showed the highest percentage of detection\u00a0<\/span><span data-contrast=\"auto\">of SARS-CoV-2 by RT-PCR\u00a0<\/span><span data-contrast=\"auto\">was from nasopharyngeal sampling between 0 to 4 days post-symptom onset at 89% (95%CI 83<\/span><span data-contrast=\"auto\">%<\/span><span data-contrast=\"auto\">-93<\/span><span data-contrast=\"auto\">%<\/span><span data-contrast=\"auto\">). The percentage dropped to 54% (95%CI 47<\/span><span data-contrast=\"auto\">%<\/span><span data-contrast=\"auto\">-61<\/span><span data-contrast=\"auto\">%<\/span><span data-contrast=\"auto\">) after 10 to 14 days.\u00a0<\/span><span data-contrast=\"auto\">Up to 30% of participants with\u00a0<\/span><span data-contrast=\"auto\">SARS-CoV-2<\/span><span data-contrast=\"auto\">\u00a0detected in respiratory samples did not have detectable fecal samples<\/span><span data-contrast=\"auto\">.\u00a0<\/span><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li>\n<\/ul>\n<p><i><span data-contrast=\"none\">Mallett et al. (July 14, 2020). At What Times during Infection Is SARS-CoV-2 Detectable and No Longer Detectable Using RT-PCR Based Tests A Systematic Review of Individual Participant Data. Pre-print\u00a0downloaded July 15 from\u00a0<\/span><\/i><a href=\"https:\/\/doi.org\/10.1101\/2020.07.13.20152793\"><span data-contrast=\"none\">https:\/\/doi.org\/10.1101\/2020.07.13.20152793<\/span><\/a><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559685&quot;:720,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"<p>[Preprint, not peer-reviewed]\u00a0A systematic review\u00a0(32 studies\u00a0with\u00a01,023 SARS-CoV-2 infected patients)\u00a0showed the highest percentage of detection\u00a0of SARS-CoV-2 by RT-PCR\u00a0was from nasopharyngeal sampling between 0 to 4 days post-symptom onset at 89% (95%CI 83%-93%). The percentage dropped to 54% (95%CI 47%-61%) after 10 to 14 days.\u00a0Up to 30% of participants with\u00a0SARS-CoV-2\u00a0detected in respiratory samples did not have detectable&#8230;<\/p>\n<div><a class=\"more\" href=\"https:\/\/depts.washington.edu\/pandemicalliance\/2020\/07\/15\/at-what-times-during-infection-is-sars-cov-2-detectable-and-no-longer-detectable-using-rt-pcr-based-tests-a-systematic-review-of-individual-participant-data\/\">Read more<\/a><\/div>\n","protected":false},"author":8,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":"","_members_access_role":[],"_members_access_error":"","_links_to":"","_links_to_target":""},"categories":[6],"tags":[],"topic":[19],"class_list":["post-8239","post","type-post","status-publish","format-standard","hentry","category-article-summary","topic-testing-and-treatment"],"_links":{"self":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/8239","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/users\/8"}],"replies":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/comments?post=8239"}],"version-history":[{"count":1,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/8239\/revisions"}],"predecessor-version":[{"id":8240,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/8239\/revisions\/8240"}],"wp:attachment":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/media?parent=8239"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/categories?post=8239"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/tags?post=8239"},{"taxonomy":"topic","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/topic?post=8239"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}