{"id":8241,"date":"2020-07-15T11:26:13","date_gmt":"2020-07-15T18:26:13","guid":{"rendered":"https:\/\/depts.washington.edu\/pandemicalliance\/?p=8241"},"modified":"2021-04-01T11:26:59","modified_gmt":"2021-04-01T18:26:59","slug":"sars-cov-2-antibody-responses-do-not-predict-covid-19-disease-severity","status":"publish","type":"post","link":"https:\/\/depts.washington.edu\/pandemicalliance\/2020\/07\/15\/sars-cov-2-antibody-responses-do-not-predict-covid-19-disease-severity\/","title":{"rendered":"SARS-CoV-2 Antibody Responses Do Not Predict COVID-19 Disease Severity"},"content":{"rendered":"<ul>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"34\" data-aria-posinset=\"2019\" data-aria-level=\"1\"><span data-contrast=\"auto\">Based on a sample of 172\u00a0<\/span><span data-contrast=\"auto\">suspected cases of SARS-CoV-2<\/span><span data-contrast=\"auto\">\u00a0and 795 negative plasma samples, IgG antibody testing had a\u00a0<\/span><span data-contrast=\"auto\">100% specificity (0\/795)\u00a0and\u00a0<\/span><span data-contrast=\"auto\">IgG tests were positive for\u00a0<\/span><span data-contrast=\"auto\">83%\u00a0<\/span><span data-contrast=\"auto\">of suspected cases\u00a0<\/span><span data-contrast=\"auto\">among samples collected more than 14 days from symptom onset.\u00a0<\/span><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"34\" data-aria-posinset=\"2019\" data-aria-level=\"1\"><span data-contrast=\"auto\">There was no<\/span><span data-contrast=\"auto\">\u00a0association\u00a0<\/span><span data-contrast=\"auto\">between the level of IgG an<\/span><span data-contrast=\"auto\">d IgM reactivity and mi<\/span><span data-contrast=\"auto\">ld<\/span><span data-contrast=\"auto\">\u00a0<\/span><span data-contrast=\"auto\">versus\u00a0<\/span><span data-contrast=\"auto\">severe disease course.<\/span><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li>\n<\/ul>\n<p><i><span data-contrast=\"none\">Phipps et al. (July 15, 2020). SARS-CoV-2 Antibody Responses Do Not Predict COVID-19 Disease Severity. American Journal of Clinical Pathology.\u00a0<\/span><\/i><a href=\"https:\/\/doi.org\/10.1093\/ajcp\/aqaa123\"><span data-contrast=\"none\">https:\/\/doi.org\/10.1093\/ajcp\/aqaa123<\/span><\/a><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559685&quot;:720,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Based on a sample of 172\u00a0suspected cases of SARS-CoV-2\u00a0and 795 negative plasma samples, IgG antibody testing had a\u00a0100% specificity (0\/795)\u00a0and\u00a0IgG tests were positive for\u00a083%\u00a0of suspected cases\u00a0among samples collected more than 14 days from symptom onset.\u00a0\u00a0 There was no\u00a0association\u00a0between the level of IgG and IgM reactivity and mild\u00a0versus\u00a0severe disease course.\u00a0 Phipps et al. (July 15, 2020)&#8230;.<\/p>\n<div><a class=\"more\" href=\"https:\/\/depts.washington.edu\/pandemicalliance\/2020\/07\/15\/sars-cov-2-antibody-responses-do-not-predict-covid-19-disease-severity\/\">Read more<\/a><\/div>\n","protected":false},"author":8,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":"","_links_to":"","_links_to_target":""},"categories":[6],"tags":[],"topic":[19],"class_list":["post-8241","post","type-post","status-publish","format-standard","hentry","category-article-summary","topic-testing-and-treatment"],"_links":{"self":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/8241","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/users\/8"}],"replies":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/comments?post=8241"}],"version-history":[{"count":1,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/8241\/revisions"}],"predecessor-version":[{"id":8242,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/8241\/revisions\/8242"}],"wp:attachment":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/media?parent=8241"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/categories?post=8241"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/tags?post=8241"},{"taxonomy":"topic","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/topic?post=8241"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}