{"id":8245,"date":"2020-07-15T11:28:25","date_gmt":"2020-07-15T18:28:25","guid":{"rendered":"https:\/\/depts.washington.edu\/pandemicalliance\/?p=8245"},"modified":"2021-04-01T11:29:10","modified_gmt":"2021-04-01T18:29:10","slug":"comparison-of-mortality-risk-in-patients-with-cirrhosis-and-covid-19-compared-with-patients-with-cirrhosis-alone-and-covid-19-alone-multicentre-matched-cohort","status":"publish","type":"post","link":"https:\/\/depts.washington.edu\/pandemicalliance\/2020\/07\/15\/comparison-of-mortality-risk-in-patients-with-cirrhosis-and-covid-19-compared-with-patients-with-cirrhosis-alone-and-covid-19-alone-multicentre-matched-cohort\/","title":{"rendered":"Comparison of Mortality Risk in Patients with Cirrhosis and COVID-19 Compared with Patients with Cirrhosis Alone and COVID-19 Alone:\u00a0Multicentre\u00a0Matched Cohort"},"content":{"rendered":"<ul>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"34\" data-aria-posinset=\"2019\" data-aria-level=\"1\"><span data-contrast=\"auto\">A multicenter study in<\/span><span data-contrast=\"auto\">\u00a0the<\/span><span data-contrast=\"auto\">\u00a0US compared 37 inpatients with cirrhosis<\/span><span data-contrast=\"auto\">\u00a0and<\/span><span data-contrast=\"auto\">\u00a0<\/span><span data-contrast=\"auto\">COVID-19 to age<\/span><span data-contrast=\"auto\">&#8211; and<\/span><span data-contrast=\"auto\">\u00a0<\/span><span data-contrast=\"auto\">gender-matched patients with COVID-19 alone (n=108) or cirrhosis alone (n=127). Results showed that patients with cirrhosis<\/span><span data-contrast=\"auto\">\u00a0and<\/span><span data-contrast=\"auto\">\u00a0<\/span><span data-contrast=\"auto\">COVID-19 had\u00a0<\/span><span data-contrast=\"auto\">a non-significant<\/span><span data-contrast=\"auto\">l<\/span><span data-contrast=\"auto\">y higher mortality\u00a0<\/span><span data-contrast=\"auto\">compared\u00a0<\/span><span data-contrast=\"auto\">to\u00a0<\/span><span data-contrast=\"auto\">patients with cirrhosis alone<\/span><span data-contrast=\"auto\">\u00a0<\/span><span data-contrast=\"auto\">(30% vs 20%, p=0.16),\u00a0<\/span><span data-contrast=\"auto\">and significantly\u00a0<\/span><span data-contrast=\"auto\">higher\u00a0<\/span><span data-contrast=\"auto\">mortality\u00a0<\/span><span data-contrast=\"auto\">than patients with COVID-19 alone (30% vs 13%, p=0.03).\u00a0<\/span><span data-contrast=\"auto\">The elevated mortality among those with cirrhosis and COVID-19 may be at least partially attributable to a higher degree of co-morbidities, as measured by the\u00a0<\/span><span data-contrast=\"auto\">Charlson Comorbidity Index.<\/span><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li>\n<\/ul>\n<p><i><span data-contrast=\"none\">Bajaj et al. (July 13, 2020). Comparison of Mortality Risk in Patients with Cirrhosis and COVID-19 Compared with Patients with Cirrhosis Alone and COVID-19 Alone:\u00a0Multicentre\u00a0Matched Cohort.\u00a0<\/span><\/i><span data-contrast=\"auto\">Gut.\u00a0<\/span><a href=\"https:\/\/doi.org\/10.1136\/gutjnl-2020-322118\"><span data-contrast=\"none\">https:\/\/doi.org\/10.1136\/gutjnl-2020-322118<\/span><\/a><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559685&quot;:720,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"<p>A multicenter study in\u00a0the\u00a0US compared 37 inpatients with cirrhosis\u00a0and\u00a0COVID-19 to age&#8211; and\u00a0gender-matched patients with COVID-19 alone (n=108) or cirrhosis alone (n=127). Results showed that patients with cirrhosis\u00a0and\u00a0COVID-19 had\u00a0a non-significantly higher mortality\u00a0compared\u00a0to\u00a0patients with cirrhosis alone\u00a0(30% vs 20%, p=0.16),\u00a0and significantly\u00a0higher\u00a0mortality\u00a0than patients with COVID-19 alone (30% vs 13%, p=0.03).\u00a0The elevated mortality among those with cirrhosis and COVID-19 may&#8230;<\/p>\n<div><a class=\"more\" href=\"https:\/\/depts.washington.edu\/pandemicalliance\/2020\/07\/15\/comparison-of-mortality-risk-in-patients-with-cirrhosis-and-covid-19-compared-with-patients-with-cirrhosis-alone-and-covid-19-alone-multicentre-matched-cohort\/\">Read more<\/a><\/div>\n","protected":false},"author":8,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":"","_links_to":"","_links_to_target":""},"categories":[6],"tags":[],"topic":[20],"class_list":["post-8245","post","type-post","status-publish","format-standard","hentry","category-article-summary","topic-clinical-characteristics-and-health-care-setting"],"_links":{"self":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/8245","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/users\/8"}],"replies":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/comments?post=8245"}],"version-history":[{"count":1,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/8245\/revisions"}],"predecessor-version":[{"id":8246,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/8245\/revisions\/8246"}],"wp:attachment":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/media?parent=8245"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/categories?post=8245"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/tags?post=8245"},{"taxonomy":"topic","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/topic?post=8245"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}