{"id":8270,"date":"2020-07-16T11:41:57","date_gmt":"2020-07-16T18:41:57","guid":{"rendered":"https:\/\/depts.washington.edu\/pandemicalliance\/?p=8270"},"modified":"2021-04-01T11:42:40","modified_gmt":"2021-04-01T18:42:40","slug":"factors-associated-with-death-in-critically-ill-patients-with-coronavirus-disease-2019-in-the-us","status":"publish","type":"post","link":"https:\/\/depts.washington.edu\/pandemicalliance\/2020\/07\/16\/factors-associated-with-death-in-critically-ill-patients-with-coronavirus-disease-2019-in-the-us\/","title":{"rendered":"Factors Associated\u00a0With\u00a0Death in Critically Ill Patients\u00a0With\u00a0Coronavirus Disease 2019 in the US"},"content":{"rendered":"<ul>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"34\" data-aria-posinset=\"2019\" data-aria-level=\"1\"><span data-contrast=\"auto\">In a US multicenter cohort study of COVID-19 patients admitted to ICU (n=2,215), independent risk factors associated with\u00a028 day\u00a0mortality included older age<\/span><span data-contrast=\"auto\">\u00a0(\u226580 vs &lt;40 years of age<\/span><span data-contrast=\"auto\">:\u00a0<\/span><span data-contrast=\"auto\">OR=11.15)<\/span><span data-contrast=\"auto\">, male sex<\/span><span data-contrast=\"auto\">\u00a0(OR=1.50)<\/span><span data-contrast=\"auto\">, obesity<\/span><span data-contrast=\"auto\">\u00a0(BMI\u00a0<\/span><span data-contrast=\"auto\">\u226540 vs &lt;25: OR<\/span><span data-contrast=\"auto\">=<\/span><span data-contrast=\"auto\">1.51<\/span><span data-contrast=\"auto\">)<\/span><span data-contrast=\"auto\">, coronary artery disease<\/span><span data-contrast=\"auto\">\u00a0(OR=1.47)<\/span><span data-contrast=\"auto\">,\u00a0<\/span><span data-contrast=\"auto\">active\u00a0<\/span><span data-contrast=\"auto\">cancer<\/span><span data-contrast=\"auto\">\u00a0(OR=2.15)<\/span><span data-contrast=\"auto\">,\u00a0<\/span><span data-contrast=\"auto\">and\u00a0<\/span><span data-contrast=\"auto\">acute organ dysfunction<\/span><span data-contrast=\"auto\">\u00a0(OR=2.43 to 2.61). Patients\u00a0<\/span><span data-contrast=\"auto\">admi<\/span><span data-contrast=\"auto\">tted<\/span><span data-contrast=\"auto\">\u00a0to a hospital with fewer ICU beds<\/span><span data-contrast=\"auto\">\u00a0had a higher risk of death (<\/span><span data-contrast=\"auto\">&lt;50 vs \u2265100 ICU beds: OR<\/span><span data-contrast=\"auto\">=<\/span><span data-contrast=\"auto\">3.28<\/span><span data-contrast=\"auto\">)<\/span><span data-contrast=\"auto\">.\u00a0<\/span><span data-contrast=\"auto\">Overall,\u00a0<\/span><span data-contrast=\"auto\">35% of the cohort died within 28 days.<\/span><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li>\n<\/ul>\n<p><i><span data-contrast=\"none\">Gupta et al. (July 15, 2020). Factors Associated\u00a0With\u00a0Death in Critically Ill Patients\u00a0With\u00a0Coronavirus Disease 2019 in the US. JAMA Internal Medicine.\u00a0<\/span><\/i><a href=\"https:\/\/doi.org\/10.1001\/jamainternmed.2020.3596\"><span data-contrast=\"none\">https:\/\/doi.org\/10.1001\/jamainternmed.2020.3596<\/span><\/a><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559685&quot;:720,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"<p>In a US multicenter cohort study of COVID-19 patients admitted to ICU (n=2,215), independent risk factors associated with\u00a028 day\u00a0mortality included older age\u00a0(\u226580 vs &lt;40 years of age:\u00a0OR=11.15), male sex\u00a0(OR=1.50), obesity\u00a0(BMI\u00a0\u226540 vs &lt;25: OR=1.51), coronary artery disease\u00a0(OR=1.47),\u00a0active\u00a0cancer\u00a0(OR=2.15),\u00a0and\u00a0acute organ dysfunction\u00a0(OR=2.43 to 2.61). Patients\u00a0admitted\u00a0to a hospital with fewer ICU beds\u00a0had a higher risk of death (&lt;50 vs \u2265100&#8230;<\/p>\n<div><a class=\"more\" href=\"https:\/\/depts.washington.edu\/pandemicalliance\/2020\/07\/16\/factors-associated-with-death-in-critically-ill-patients-with-coronavirus-disease-2019-in-the-us\/\">Read more<\/a><\/div>\n","protected":false},"author":8,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":"","_links_to":"","_links_to_target":""},"categories":[6],"tags":[],"topic":[20],"class_list":["post-8270","post","type-post","status-publish","format-standard","hentry","category-article-summary","topic-clinical-characteristics-and-health-care-setting"],"_links":{"self":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/8270","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/users\/8"}],"replies":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/comments?post=8270"}],"version-history":[{"count":1,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/8270\/revisions"}],"predecessor-version":[{"id":8271,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/8270\/revisions\/8271"}],"wp:attachment":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/media?parent=8270"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/categories?post=8270"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/tags?post=8270"},{"taxonomy":"topic","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/topic?post=8270"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}