{"id":8291,"date":"2021-04-01T14:48:43","date_gmt":"2021-04-01T21:48:43","guid":{"rendered":"https:\/\/depts.washington.edu\/pandemicalliance\/?p=8291"},"modified":"2021-04-02T14:49:48","modified_gmt":"2021-04-02T21:49:48","slug":"covid-19-vaccine-impact-on-rates-of-sars-cov-2-cases-and-post-vaccination-strain-sequences-among-healthcare-workers-at-an-urban-academic-medical-center-a-prospective-cohort-study","status":"publish","type":"post","link":"https:\/\/depts.washington.edu\/pandemicalliance\/2021\/04\/01\/covid-19-vaccine-impact-on-rates-of-sars-cov-2-cases-and-post-vaccination-strain-sequences-among-healthcare-workers-at-an-urban-academic-medical-center-a-prospective-cohort-study\/","title":{"rendered":"COVID-19 Vaccine Impact on Rates of SARS-CoV-2 Cases and Post Vaccination Strain Sequences among Healthcare Workers at an Urban Academic Medical Center a Prospective Cohort Study"},"content":{"rendered":"<ul>\n<li style=\"font-weight: 400\"><i><span style=\"font-weight: 400\">[Pre-print, not peer-reviewed]<\/span><\/i><span style=\"font-weight: 400\"> Among a cohort of healthcare workers (HCW) from Boston Medical Center who received the first dose of either the Pfizer-BioNTech or Moderna vaccines, the SARS-CoV-2 infection rate was 27% and 82% lower 1-14 days and &gt;14 days after receiving the first dose, respectively, compared to surrounding community infection rates. SARS-CoV-2 infections occurred in 1.4% (96 of 7109) of HCWs given at least a first dose and 0.3% (17 of 5913) of HCWs given both doses. SARS-CoV-2 infections &gt;14 days from the first dose were more frequently asymptomatic, among older HCWs, and HCWs of Latinx ethnicity. Analysis of 48 SARS-CoV-2 genomes sequenced from first-dose infections did not indicate selection pressure towards mutations in the spike protein known to escape antibody neutralization.<\/span><\/li>\n<\/ul>\n<p><i><span style=\"font-weight: 400\">Bouton et al.\u00a0(Mar 31, 2021). COVID-19 Vaccine Impact on Rates of SARS-CoV-2 Cases and Post Vaccination Strain Sequences among Healthcare Workers at an Urban Academic Medical Center a Prospective Cohort Study. Pre-print downloaded Apr 1 from <\/span><\/i><a href=\"https:\/\/doi.org\/10.1101\/2021.03.30.21254655\"><span style=\"font-weight: 400\">https:\/\/doi.org\/10.1101\/2021.03.30.21254655<\/span><\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>[Pre-print, not peer-reviewed] Among a cohort of healthcare workers (HCW) from Boston Medical Center who received the first dose of either the Pfizer-BioNTech or Moderna vaccines, the SARS-CoV-2 infection rate was 27% and 82% lower 1-14 days and &gt;14 days after receiving the first dose, respectively, compared to surrounding community infection rates. SARS-CoV-2 infections occurred&#8230;<\/p>\n<div><a class=\"more\" href=\"https:\/\/depts.washington.edu\/pandemicalliance\/2021\/04\/01\/covid-19-vaccine-impact-on-rates-of-sars-cov-2-cases-and-post-vaccination-strain-sequences-among-healthcare-workers-at-an-urban-academic-medical-center-a-prospective-cohort-study\/\">Read more<\/a><\/div>\n","protected":false},"author":8,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":"","_links_to":"","_links_to_target":""},"categories":[6],"tags":[154,187],"topic":[31],"class_list":["post-8291","post","type-post","status-publish","format-standard","hentry","category-article-summary","tag-healthcare-workers","tag-vaccinations","topic-vaccines-and-immunity"],"_links":{"self":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/8291","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/users\/8"}],"replies":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/comments?post=8291"}],"version-history":[{"count":1,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/8291\/revisions"}],"predecessor-version":[{"id":8292,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/8291\/revisions\/8292"}],"wp:attachment":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/media?parent=8291"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/categories?post=8291"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/tags?post=8291"},{"taxonomy":"topic","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/topic?post=8291"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}