{"id":8293,"date":"2021-04-01T14:49:52","date_gmt":"2021-04-01T21:49:52","guid":{"rendered":"https:\/\/depts.washington.edu\/pandemicalliance\/?p=8293"},"modified":"2021-04-02T14:51:23","modified_gmt":"2021-04-02T21:51:23","slug":"longitudinal-dynamics-of-antibody-responses-in-recovered-covid-19-patients","status":"publish","type":"post","link":"https:\/\/depts.washington.edu\/pandemicalliance\/2021\/04\/01\/longitudinal-dynamics-of-antibody-responses-in-recovered-covid-19-patients\/","title":{"rendered":"Longitudinal Dynamics of Antibody Responses in Recovered COVID-19 Patients"},"content":{"rendered":"<ul>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">SARS-CoV-2-specific IgG antibody titers gradually increased with neutralizing antibody titers while IgM titers more quickly waned in a study of the antibody response dynamics in 24 COVID-19 recovered patients followed up to 42 weeks. While IgG titers were higher among severe than among mild cases, titers did not decline significantly over time in either group. 17% of patients were IgM-negative by 8-11 weeks, and the proportion continued to increase during the following weeks. Neutralizing antibody titers initially showed significant drops up to week 13, but remained stable through 42 weeks.<\/span><\/li>\n<\/ul>\n<p><i><span style=\"font-weight: 400\">Cheng et al.\u00a0(Mar 31, 2021). Longitudinal Dynamics of Antibody Responses in Recovered COVID-19 Patients. Signal Transduction and Targeted Therapy. <\/span><\/i><a href=\"https:\/\/doi.org\/10.1038\/s41392-021-00559-7\"><span style=\"font-weight: 400\">https:\/\/doi.org\/10.1038\/s41392-021-00559-7<\/span><\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>SARS-CoV-2-specific IgG antibody titers gradually increased with neutralizing antibody titers while IgM titers more quickly waned in a study of the antibody response dynamics in 24 COVID-19 recovered patients followed up to 42 weeks. While IgG titers were higher among severe than among mild cases, titers did not decline significantly over time in either group&#8230;.<\/p>\n<div><a class=\"more\" href=\"https:\/\/depts.washington.edu\/pandemicalliance\/2021\/04\/01\/longitudinal-dynamics-of-antibody-responses-in-recovered-covid-19-patients\/\">Read more<\/a><\/div>\n","protected":false},"author":8,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":"","_links_to":"","_links_to_target":""},"categories":[6],"tags":[67,32],"topic":[31],"class_list":["post-8293","post","type-post","status-publish","format-standard","hentry","category-article-summary","tag-antibodies","tag-immunity","topic-vaccines-and-immunity"],"_links":{"self":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/8293","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/users\/8"}],"replies":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/comments?post=8293"}],"version-history":[{"count":1,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/8293\/revisions"}],"predecessor-version":[{"id":8294,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/8293\/revisions\/8294"}],"wp:attachment":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/media?parent=8293"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/categories?post=8293"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/tags?post=8293"},{"taxonomy":"topic","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/topic?post=8293"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}