{"id":8346,"date":"2020-07-20T15:34:35","date_gmt":"2020-07-20T22:34:35","guid":{"rendered":"https:\/\/depts.washington.edu\/pandemicalliance\/?p=8346"},"modified":"2021-04-02T15:35:21","modified_gmt":"2021-04-02T22:35:21","slug":"going-beyond-clinical-routine-in-sars-cov-2-antibody-testing-a-multiplex-corona-virus-antibody-test-for-the-evaluation-of-cross-reactivity-to-endemic-coronavirus-antigens","status":"publish","type":"post","link":"https:\/\/depts.washington.edu\/pandemicalliance\/2020\/07\/20\/going-beyond-clinical-routine-in-sars-cov-2-antibody-testing-a-multiplex-corona-virus-antibody-test-for-the-evaluation-of-cross-reactivity-to-endemic-coronavirus-antigens\/","title":{"rendered":"Going beyond Clinical Routine in SARS-CoV-2 Antibody Testing &#8211; A Multiplex Corona Virus Antibody Test for the Evaluation of Cross-Reactivity to Endemic Coronavirus Antigens"},"content":{"rendered":"<ul>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"34\" data-aria-posinset=\"2019\" data-aria-level=\"1\"><i><span data-contrast=\"none\">[pre-print, not peer-reviewed]<\/span><\/i><span data-contrast=\"auto\">\u00a0Becker et al. developed a multiplexed immunoassay to measure IgG and IgA responses against\u00a0<\/span><span data-contrast=\"auto\">six\u00a0<\/span><span data-contrast=\"auto\">SARS-CoV-2<\/span><span data-contrast=\"auto\">\u00a0antigens<\/span><span data-contrast=\"auto\">, achieving a sensitivity of 90% and a specificity of 100%. By monitoring IgA response, they were able to detect an early immune response in some patients.\u00a0<\/span><span data-contrast=\"auto\">The authors suggest that t<\/span><span data-contrast=\"auto\">he\u00a0<\/span><span data-contrast=\"auto\">test may be useful in monitoring vaccination studies and conducting widespread screening.\u00a0<\/span><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li>\n<\/ul>\n<p><i><span data-contrast=\"none\">Becker et al. (July 17, 2020). Going beyond Clinical Routine in SARS-CoV-2 Antibody Testing &#8211; A Multiplex Corona Virus Antibody Test for the Evaluation of Cross-Reactivity to Endemic Coronavirus Antigens.\u00a0<\/span><\/i><i><span data-contrast=\"none\">Pre-print\u00a0downloaded July 20 from\u00a0<\/span><\/i><a href=\"https:\/\/doi.org\/10.1101\/2020.07.17.20156000\"><span data-contrast=\"none\">https:\/\/doi.org\/10.1101\/2020.07.17.20156000<\/span><\/a><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559685&quot;:720,&quot;335559739&quot;:160,&quot;335559740&quot;:240}\">\u00a0<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"<p>[pre-print, not peer-reviewed]\u00a0Becker et al. developed a multiplexed immunoassay to measure IgG and IgA responses against\u00a0six\u00a0SARS-CoV-2\u00a0antigens, achieving a sensitivity of 90% and a specificity of 100%. By monitoring IgA response, they were able to detect an early immune response in some patients.\u00a0The authors suggest that the\u00a0test may be useful in monitoring vaccination studies and conducting&#8230;<\/p>\n<div><a class=\"more\" href=\"https:\/\/depts.washington.edu\/pandemicalliance\/2020\/07\/20\/going-beyond-clinical-routine-in-sars-cov-2-antibody-testing-a-multiplex-corona-virus-antibody-test-for-the-evaluation-of-cross-reactivity-to-endemic-coronavirus-antigens\/\">Read more<\/a><\/div>\n","protected":false},"author":8,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":"","_links_to":"","_links_to_target":""},"categories":[6],"tags":[],"topic":[19],"class_list":["post-8346","post","type-post","status-publish","format-standard","hentry","category-article-summary","topic-testing-and-treatment"],"_links":{"self":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/8346","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/users\/8"}],"replies":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/comments?post=8346"}],"version-history":[{"count":1,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/8346\/revisions"}],"predecessor-version":[{"id":8347,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/8346\/revisions\/8347"}],"wp:attachment":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/media?parent=8346"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/categories?post=8346"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/tags?post=8346"},{"taxonomy":"topic","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/topic?post=8346"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}