{"id":8354,"date":"2020-07-20T15:38:34","date_gmt":"2020-07-20T22:38:34","guid":{"rendered":"https:\/\/depts.washington.edu\/pandemicalliance\/?p=8354"},"modified":"2021-04-02T15:39:17","modified_gmt":"2021-04-02T22:39:17","slug":"histopathology-and-ultrastructural-findings-of-fatal-covid-19-infections-in-washington-state-a-case-series","status":"publish","type":"post","link":"https:\/\/depts.washington.edu\/pandemicalliance\/2020\/07\/20\/histopathology-and-ultrastructural-findings-of-fatal-covid-19-infections-in-washington-state-a-case-series\/","title":{"rendered":"Histopathology and Ultrastructural Findings of Fatal COVID-19 Infections in Washington State: A Case Series"},"content":{"rendered":"<ul>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"34\" data-aria-posinset=\"2019\" data-aria-level=\"1\"><span data-contrast=\"auto\">In conducting post-mortem examinations of 14 people who died with COVID-19<\/span><span data-contrast=\"auto\">\u00a0in Washington state<\/span><span data-contrast=\"auto\">, Bradley et al. found\u00a0<\/span><span data-contrast=\"auto\">coronavirus-like particles in the respiratory system, kidney, and gastrointestinal tract<\/span><span data-contrast=\"auto\">.<\/span><span data-contrast=\"auto\">\u00a0<\/span><span data-contrast=\"auto\">One<\/span><span data-contrast=\"auto\">\u00a0<\/span><span data-contrast=\"auto\">decedent<\/span><span data-contrast=\"auto\">\u00a0had findings of lymphocytic myocarditis, with\u00a0<\/span><span data-contrast=\"auto\">SARS-CoV-2\u00a0<\/span><span data-contrast=\"auto\">RNA\u00a0<\/span><span data-contrast=\"auto\">detected in the\u00a0<\/span><span data-contrast=\"auto\">myocardial<\/span><span data-contrast=\"auto\">\u00a0tissue.\u00a0<\/span><span data-contrast=\"auto\">A<\/span><span data-contrast=\"auto\">ll patients had\u00a0<\/span><span data-contrast=\"auto\">clinically-significant\u00a0<\/span><span data-contrast=\"auto\">comorbidities, with the most common being hypertension, chronic kidney disease, obstructive sleep apnea, and metabolic disease including diabetes and obesity.<\/span><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li>\n<\/ul>\n<p><i><span data-contrast=\"none\">Bradley et al. (July 16, 2020). Histopathology and Ultrastructural Findings of Fatal COVID-19 Infections in Washington State: A Case Series. The Lancet.\u00a0<\/span><\/i><a href=\"https:\/\/doi.org\/10.1016\/S0140-6736(20)31305-2\"><span data-contrast=\"none\">https:\/\/doi.org\/10.1016\/S0140-6736(20)31305-2<\/span><\/a><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559685&quot;:720,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"<p>In conducting post-mortem examinations of 14 people who died with COVID-19\u00a0in Washington state, Bradley et al. found\u00a0coronavirus-like particles in the respiratory system, kidney, and gastrointestinal tract.\u00a0One\u00a0decedent\u00a0had findings of lymphocytic myocarditis, with\u00a0SARS-CoV-2\u00a0RNA\u00a0detected in the\u00a0myocardial\u00a0tissue.\u00a0All patients had\u00a0clinically-significant\u00a0comorbidities, with the most common being hypertension, chronic kidney disease, obstructive sleep apnea, and metabolic disease including diabetes and obesity.\u00a0 Bradley&#8230;<\/p>\n<div><a class=\"more\" href=\"https:\/\/depts.washington.edu\/pandemicalliance\/2020\/07\/20\/histopathology-and-ultrastructural-findings-of-fatal-covid-19-infections-in-washington-state-a-case-series\/\">Read more<\/a><\/div>\n","protected":false},"author":8,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":"","_links_to":"","_links_to_target":""},"categories":[6],"tags":[],"topic":[20],"class_list":["post-8354","post","type-post","status-publish","format-standard","hentry","category-article-summary","topic-clinical-characteristics-and-health-care-setting"],"_links":{"self":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/8354","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/users\/8"}],"replies":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/comments?post=8354"}],"version-history":[{"count":1,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/8354\/revisions"}],"predecessor-version":[{"id":8355,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/8354\/revisions\/8355"}],"wp:attachment":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/media?parent=8354"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/categories?post=8354"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/tags?post=8354"},{"taxonomy":"topic","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/topic?post=8354"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}