{"id":8474,"date":"2020-07-24T10:04:56","date_gmt":"2020-07-24T17:04:56","guid":{"rendered":"https:\/\/depts.washington.edu\/pandemicalliance\/?p=8474"},"modified":"2021-04-05T10:06:50","modified_gmt":"2021-04-05T17:06:50","slug":"spatial-and-temporal-dynamics-of-sars-cov-2-in-covid-19-patients-a-systematic-review-and-meta-analysis","status":"publish","type":"post","link":"https:\/\/depts.washington.edu\/pandemicalliance\/2020\/07\/24\/spatial-and-temporal-dynamics-of-sars-cov-2-in-covid-19-patients-a-systematic-review-and-meta-analysis\/","title":{"rendered":"Spatial and Temporal Dynamics of SARS-CoV-2 in COVID-19 Patients:\u00a0A Systematic\u00a0Review and Meta-Analysis"},"content":{"rendered":"<ul>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"43\" data-aria-posinset=\"1\" data-aria-level=\"1\"><span data-contrast=\"auto\">A systematic literature review (<\/span><span data-contrast=\"auto\">37 studies, 22 used in meta-analysis) showed consistent recovery of SARS-CoV-2 genetic material from the upper respiratory tract (URT), the lower respiratory tract (LRT), and the feces, regardless of clinical severity. SARS-CoV-2 was found to persist for longer in moderate-to-severe patients\u00a0<\/span><span data-contrast=\"auto\">versus\u00a0<\/span><span data-contrast=\"auto\">mild patients for both the URT and feces, and to persist for longer in the LRT than URT in adult patients. Viral load was also found to peak in earlier stages of infection in the URT\u00a0<\/span><span data-contrast=\"auto\">compared to\u00a0<\/span><span data-contrast=\"auto\">the LRT.\u00a0\u00a0<\/span><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li>\n<\/ul>\n<p><i><span data-contrast=\"none\">Weiss et al. (Aug 1, 2020). Spatial and Temporal Dynamics of SARS-CoV-2 in COVID-19 Patients:\u00a0A Systematic\u00a0Review and Meta-Analysis.\u00a0EBioMedicine.\u00a0<\/span><\/i><a href=\"https:\/\/doi.org\/10.1016\/j.ebiom.2020.102916\"><span data-contrast=\"none\">https:\/\/doi.org\/10.1016\/j.ebiom.2020.102916<\/span><\/a><span data-ccp-props=\"{&quot;201341983&quot;:0,&quot;335559685&quot;:720,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"<p>A systematic literature review (37 studies, 22 used in meta-analysis) showed consistent recovery of SARS-CoV-2 genetic material from the upper respiratory tract (URT), the lower respiratory tract (LRT), and the feces, regardless of clinical severity. SARS-CoV-2 was found to persist for longer in moderate-to-severe patients\u00a0versus\u00a0mild patients for both the URT and feces, and to persist&#8230;<\/p>\n<div><a class=\"more\" href=\"https:\/\/depts.washington.edu\/pandemicalliance\/2020\/07\/24\/spatial-and-temporal-dynamics-of-sars-cov-2-in-covid-19-patients-a-systematic-review-and-meta-analysis\/\">Read more<\/a><\/div>\n","protected":false},"author":8,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":"","_links_to":"","_links_to_target":""},"categories":[6],"tags":[],"topic":[19],"class_list":["post-8474","post","type-post","status-publish","format-standard","hentry","category-article-summary","topic-testing-and-treatment"],"_links":{"self":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/8474","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/users\/8"}],"replies":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/comments?post=8474"}],"version-history":[{"count":1,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/8474\/revisions"}],"predecessor-version":[{"id":8475,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/8474\/revisions\/8475"}],"wp:attachment":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/media?parent=8474"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/categories?post=8474"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/tags?post=8474"},{"taxonomy":"topic","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/topic?post=8474"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}