{"id":8492,"date":"2020-07-27T10:21:48","date_gmt":"2020-07-27T17:21:48","guid":{"rendered":"https:\/\/depts.washington.edu\/pandemicalliance\/?p=8492"},"modified":"2021-04-05T10:35:56","modified_gmt":"2021-04-05T17:35:56","slug":"covid-19-literature-situation-report-july-27-2020","status":"publish","type":"post","link":"https:\/\/depts.washington.edu\/pandemicalliance\/2020\/07\/27\/covid-19-literature-situation-report-july-27-2020\/","title":{"rendered":"COVID-19 Literature Situation Report July 27, 2020"},"content":{"rendered":"<p>The scientific literature on COVID-19 is rapidly evolving and these articles were selected for review based on their relevance to Washington State decision making around COVID-19 response efforts. Included in these Lit Reps are some manuscripts that have been made available online as pre-prints but have not yet undergone peer review. Please be aware of this when reviewing articles included in the Lit Reps.<\/p>\n<h2>Key Takeaways<\/h2>\n<ul>\n<li><b><span data-contrast=\"auto\">Analysis of PCR test results from a national reference laboratory found that the median age of people\u00a0<\/span><\/b><b><span data-contrast=\"auto\">testing positive for SARS-CoV-2 in the US\u00a0<\/span><\/b><b><span data-contrast=\"auto\">has declined from 4<\/span><\/b><b><span data-contrast=\"auto\">1<\/span><\/b><b><span data-contrast=\"auto\">\u00a0years\u00a0<\/span><\/b><b><span data-contrast=\"auto\">in\u00a0<\/span><\/b><b><span data-contrast=\"auto\">April-May<\/span><\/b><b><span data-contrast=\"auto\">\u00a0<\/span><\/b><b><span data-contrast=\"auto\">to 3<\/span><\/b><b><span data-contrast=\"auto\">6<\/span><\/b><b><span data-contrast=\"auto\">\u00a0years\u00a0<\/span><\/b><b><span data-contrast=\"auto\">in\u00a0<\/span><\/b><b><span data-contrast=\"auto\">J<\/span><\/b><b><span data-contrast=\"auto\">une-July<\/span><\/b><b><span data-contrast=\"auto\">.<\/span><\/b><span data-contrast=\"auto\">\u00a0<\/span><a href=\"https:\/\/doi.org\/10.1101\/2020.07.22.20160119\"><span data-contrast=\"none\">More<\/span><\/a><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li>\n<li data-leveltext=\"\uf0d8\" data-font=\"Wingdings\" data-listid=\"1\" data-aria-posinset=\"1\" data-aria-level=\"1\"><b><span data-contrast=\"auto\">A national survey of US parents\u00a0<\/span><\/b><b><span data-contrast=\"auto\">(n=1,011) with at least\u00a0<\/span><\/b><b><span data-contrast=\"auto\">one<\/span><\/b><b><span data-contrast=\"auto\">\u00a0<\/span><\/b><b><span data-contrast=\"auto\">child\u00a0<\/span><\/b><b><span data-contrast=\"auto\">under\u00a0<\/span><\/b><b><span data-contrast=\"auto\">18 years old showed nearly 1 in 10 families experienc<\/span><\/b><b><span data-contrast=\"auto\">ed<\/span><\/b><b><span data-contrast=\"auto\">\u00a0both declining mental health of parents and declining behavioral health of children<\/span><\/b><b><span data-contrast=\"auto\">\u00a0due to the COVID-19 pandemic<\/span><\/b><b><span data-contrast=\"auto\">.<\/span><\/b><span data-contrast=\"auto\">\u00a0<\/span><a href=\"https:\/\/doi.org\/10.1542\/peds.2020-016824\"><span data-contrast=\"none\">More<\/span><\/a><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li>\n<li data-leveltext=\"\uf0d8\" data-font=\"Wingdings\" data-listid=\"1\" data-aria-posinset=\"2\" data-aria-level=\"1\"><b><span data-contrast=\"auto\">A prospective multicenter study of pediatric patients in France\u00a0<\/span><\/b><b><span data-contrast=\"auto\">found\u00a0<\/span><\/b><b><span data-contrast=\"auto\">that a symptom-based SARS-CoV-2 testing strategy failed to identify 45%<\/span><\/b><b><span data-contrast=\"auto\">\u00a0<\/span><\/b><b><span data-contrast=\"auto\">of hospitalized SARS-CoV-2 infected children<\/span><\/b><b><span data-contrast=\"auto\">\u00a0at the time of admission<\/span><\/b><b><span data-contrast=\"auto\">.<\/span><\/b><span data-contrast=\"auto\">\u00a0<\/span><a href=\"https:\/\/doi.org\/10.1093\/cid\/ciaa1044\"><span data-contrast=\"none\">More<\/span><\/a><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li>\n<li data-leveltext=\"\uf0d8\" data-font=\"Wingdings\" data-listid=\"1\" data-aria-posinset=\"3\" data-aria-level=\"1\"><b><span data-contrast=\"auto\">An online\u00a0<\/span><\/b><b><span data-contrast=\"auto\">social media\u00a0<\/span><\/b><b><span data-contrast=\"auto\">survey showed that participants<\/span><\/b><b><span data-contrast=\"auto\">\u00a0<\/span><\/b><b><span data-contrast=\"auto\">favored tests with\u00a0<\/span><\/b><b><span data-contrast=\"auto\">a lower\u00a0<\/span><\/b><b><span data-contrast=\"auto\">degree of contact\u00a0<\/span><\/b><b><span data-contrast=\"auto\">and greater convenience\u00a0<\/span><\/b><b><span data-contrast=\"auto\">(e.g.\u00a0home-based tests)<\/span><\/b><b><span data-contrast=\"auto\">\u00a0and that they would be more likely to test if there was a home testing option<\/span><\/b><b><span data-contrast=\"auto\">.<\/span><\/b><span data-contrast=\"auto\">\u00a0<\/span><a href=\"https:\/\/doi.org\/10.1093\/ofid\/ofaa269\"><span data-contrast=\"none\">More<\/span><\/a><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li>\n<\/ul>\n<div id=\"uw-accordion-shortcode\">\n<h3>Article Summaries<\/h3>\n<div class=\"js-accordion\" data-accordion-prefix-classes=\"uw-accordion-shortcode\">\n<div class=\"js-accordion__panel\" >\n<h2 class=\"js-accordion__header\"><span class=\"TextRun SCXW173333515 BCX0\" lang=\"EN-US\" xml:lang=\"EN-US\" data-contrast=\"none\"><span class=\"NormalTextRun SCXW173333515 BCX0\" data-ccp-parastyle=\"heading 2\">Testing and Treatment<\/span><\/span><\/h2>\n<div class=\"su-posts su-posts-default-loop\">\n<div id=\"su-post-8506\" class=\"su-post\">\n<h5 class=\"su-post-title\">SARS-CoV-2-IgG Response Is Different in COVID-19 Outpatients and Asymptomatic Contact Persons<\/h5>\n<p>\t\t\t\t<!-- \n\n\n\n\n\n\n\n\n\n\n\n<div class=\"su-post-meta\">\n\t\t\t\t\t: \t\t\t\t<\/div>\n\n\n\n\n\n\n\n\n\n\n\n --><\/p>\n<div class=\"su-post-excerpt\">\n<ul>\n<li><span data-contrast=\"auto\">Wellinghausen<\/span><span data-contrast=\"auto\">\u00a0et al. conducted\u00a0<\/span><span data-contrast=\"auto\">a\u00a0<\/span><span data-contrast=\"auto\">retrospective analysis of serum samples (n=158) from a German cohort of PCR confirmed COVID-19 outpatients and asymptomatic contact persons (n=158) and found that overall positivity rate for SARS-CoV-2-IgG was 81% among outpatients and 15% among asymptomatic contact<\/span><span data-contrast=\"auto\">s<\/span><span data-contrast=\"auto\">.<\/span><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"34\" data-aria-posinset=\"2019\" data-aria-level=\"1\"><span data-contrast=\"auto\">Symptomatic outpatients had a higher viral load, based on PCR cycle counts, compared to\u00a0<\/span><span data-contrast=\"auto\">asymptomatic contact<\/span><span data-contrast=\"auto\">s (5-7\u00a0<\/span><span data-contrast=\"auto\">threshold cycles<\/span><span data-contrast=\"auto\">)<\/span><span data-contrast=\"auto\">.<\/span><span data-contrast=\"auto\">\u00a0Viral load was also positively correlated with\u00a0<\/span><span data-contrast=\"auto\">SARS-<\/span><span data-contrast=\"auto\">CoV-2-IgG<\/span><span data-contrast=\"auto\">\u00a0ratio. The authors hypothesize that the lower viral load in asymptomatic cases could explain the lower\u00a0sero-prevalence in those without symptoms.<\/span><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li>\n<\/ul>\n<p><i><span data-contrast=\"none\">Wellinghausen\u00a0et al. (July 6, 2020). SARS-CoV-2-IgG Response Is Different in COVID-19 Outpatients and Asymptomatic Contact Persons. Journal of Clinical Virology.\u00a0<\/span><\/i><a href=\"https:\/\/doi.org\/10.1016\/j.jcv.2020.104542\"><span data-contrast=\"none\">https:\/\/doi.org\/10.1016\/j.jcv.2020.104542<\/span><\/a><i><span data-contrast=\"none\">\u00a0<\/span><\/i><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559685&quot;:720,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/p>\n<\/p>\n<\/div>\n<p>\t\t\t\t\t\t\t\t\t<!-- <a href=\"\" class=\"su-post-comments-link\"><\/a> --><\/p>\n<\/div>\n<div id=\"su-post-8504\" class=\"su-post\">\n<h5 class=\"su-post-title\">Retrospective Multicenter Cohort Study Shows Early Interferon Therapy Is Associated with Favorable Clinical Responses in COVID-19 Patients<\/h5>\n<p>\t\t\t\t<!-- \n\n\n\n\n\n\n\n\n\n\n\n<div class=\"su-post-meta\">\n\t\t\t\t\t: \t\t\t\t<\/div>\n\n\n\n\n\n\n\n\n\n\n\n --><\/p>\n<div class=\"su-post-excerpt\">\n<ul>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"34\" data-aria-posinset=\"2019\" data-aria-level=\"1\"><span data-contrast=\"auto\">Based on a\u00a0<\/span><span data-contrast=\"auto\">retrospective cohort study of COVID-19 patients in Hubei, China (n=446)<\/span><span data-contrast=\"auto\">,<\/span><span data-contrast=\"auto\">\u00a0early administration of interferon-a2b was associated with\u00a0<\/span><span data-contrast=\"auto\">lower likelihood of<\/span><span data-contrast=\"auto\">\u00a0<\/span><span data-contrast=\"auto\">in-hospital mortality\u00a0<\/span><span data-contrast=\"auto\">versus no interferon\u00a0<\/span><span data-contrast=\"auto\">(OR=0.05, 95% CI: 0.01-0.37)<\/span><span data-contrast=\"auto\">,<\/span><span data-contrast=\"auto\">\u00a0while late interferon therapy\u00a0<\/span><span data-contrast=\"auto\">was associated with greater likelihood\u00a0<\/span><span data-contrast=\"auto\">of mortality (OR=6.82, 95% CI: 1.14-40.8)<\/span><span data-contrast=\"auto\">. This may indicate that\u00a0<\/span><span data-contrast=\"auto\">the timing for interferon therapy may be\u00a0<\/span><span data-contrast=\"auto\">important<\/span><span data-contrast=\"auto\">.<\/span><span data-contrast=\"auto\">\u00a0<\/span><span data-contrast=\"auto\">Most<\/span><span data-contrast=\"auto\">\u00a0of the patients in the study who received interferon also received\u00a0<\/span><span data-contrast=\"auto\">the antiviral<\/span><span data-contrast=\"auto\">\u00a0agents\u00a0<\/span><span data-contrast=\"auto\">umifenovir\u00a0or\u00a0<\/span><span data-contrast=\"auto\">lopinavir boosted with ritonavir<\/span><span data-contrast=\"auto\">.<\/span><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li>\n<\/ul>\n<p><i><span data-contrast=\"none\">Wang et al. (July 18, 2020). Retrospective Multicenter Cohort Study Shows Early Interferon Therapy Is Associated with Favorable Clinical Responses in COVID-19 Patients. Cell Host &amp; Microbe.\u00a0<\/span><\/i><a href=\"https:\/\/doi.org\/10.1016\/j.chom.2020.07.005\"><span data-contrast=\"none\">https:\/\/doi.org\/10.1016\/j.chom.2020.07.005<\/span><\/a><i><span data-contrast=\"none\">\u00a0<\/span><\/i><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559685&quot;:720,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/p>\n<\/p>\n<\/div>\n<p>\t\t\t\t\t\t\t\t\t<!-- <a href=\"\" class=\"su-post-comments-link\"><\/a> --><\/p>\n<\/div>\n<div id=\"su-post-8502\" class=\"su-post\">\n<h5 class=\"su-post-title\">Point-of-Care Serological Assays for Delayed SARS-CoV-2 Case Identification among Health-Care Workers in the UK: A Prospective\u00a0Multicentre\u00a0Cohort Study<\/h5>\n<p>\t\t\t\t<!-- \n\n\n\n\n\n\n\n\n\n\n\n<div class=\"su-post-meta\">\n\t\t\t\t\t: \t\t\t\t<\/div>\n\n\n\n\n\n\n\n\n\n\n\n --><\/p>\n<div class=\"su-post-excerpt\">\n<ul>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"34\" data-aria-posinset=\"2019\" data-aria-level=\"1\"><span data-contrast=\"auto\">A multicenter cohort study based in the UK\u00a0<\/span><span data-contrast=\"auto\">found that\u00a0<\/span><span data-contrast=\"auto\">lateral flow\u00a0<\/span><span data-contrast=\"auto\">point-of-care\u00a0<\/span><span data-contrast=\"auto\">and ELISA tests for SARS-CoV-2\u00a0<\/span><span data-contrast=\"auto\">antibodies\u00a0<\/span><span data-contrast=\"auto\">had good positive and negative predictive values when conducted among a\u00a0<\/span><span data-contrast=\"auto\">carefully selected population with suspected SARS-CoV-2 infection.\u00a0<\/span><span data-contrast=\"auto\">The authors conclude that\u00a0these test\u00a0have potential for late case identification\u00a0<\/span><span data-contrast=\"auto\">among healthcare\u00a0<\/span><span data-contrast=\"auto\">workers<\/span><span data-contrast=\"auto\">\u00a0with mild to moderate SARS-CoV-2\u00a0<\/span><span data-contrast=\"auto\">infection<\/span><span data-contrast=\"auto\">, but also discuss important limitations, including late development of\u00a0<\/span><span data-contrast=\"auto\">bands on lateral flow assays that may limit their application.<\/span><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li>\n<\/ul>\n<p><i><span data-contrast=\"none\">Pallett et al. (July 24, 2020). Point-of-Care Serological Assays for Delayed SARS-CoV-2 Case Identification among Health-Care Workers in the UK: A Prospective\u00a0Multicentre\u00a0Cohort Study.\u00a0The Lancet\u00a0Respiratory Medicine.\u00a0<\/span><\/i><a href=\"https:\/\/doi.org\/10.1016\/S2213-2600(20)30315-5\"><span data-contrast=\"none\">https:\/\/doi.org\/10.1016\/S2213-2600(20)30315-5<\/span><\/a><i><span data-contrast=\"none\">\u00a0<\/span><\/i><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559685&quot;:720,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/p>\n<\/p>\n<\/div>\n<p>\t\t\t\t\t\t\t\t\t<!-- <a href=\"\" class=\"su-post-comments-link\"><\/a> --><\/p>\n<\/div>\n<div id=\"su-post-8500\" class=\"su-post\">\n<h5 class=\"su-post-title\">Comparison of Viral Levels in Individuals with or without Symptoms at Time of COVID-19 Testing among 32480 Residents and Staff of Nursing Homes and Assisted Living Facilities in Massachusetts<\/h5>\n<p>\t\t\t\t<!-- \n\n\n\n\n\n\n\n\n\n\n\n<div class=\"su-post-meta\">\n\t\t\t\t\t: \t\t\t\t<\/div>\n\n\n\n\n\n\n\n\n\n\n\n --><\/p>\n<div class=\"su-post-excerpt\">\n<ul>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"34\" data-aria-posinset=\"2019\" data-aria-level=\"1\"><i><span data-contrast=\"none\">[Pre-print, not peer reviewed]<\/span><\/i><i><span data-contrast=\"none\">\u00a0<\/span><\/i><span data-contrast=\"auto\">Based on PCR testing for SARS-CoV-2 among nursing home residents (n=<\/span><span data-contrast=\"auto\">16,966<\/span><span data-contrast=\"auto\">)<\/span><span data-contrast=\"auto\">\u00a0<\/span><span data-contrast=\"auto\">and staff (n=<\/span><span data-contrast=\"auto\">15,514<\/span><span data-contrast=\"auto\">)\u00a0<\/span><span data-contrast=\"auto\">with or without symptoms\u00a0<\/span><span data-contrast=\"auto\">in Massachusetts\u00a0<\/span><span data-contrast=\"auto\">(<\/span><span data-contrast=\"auto\">April 9 to June 9<\/span><span data-contrast=\"auto\">),\u00a0<\/span><span data-contrast=\"auto\">1<\/span><span data-contrast=\"auto\">3<\/span><span data-contrast=\"auto\">% of residents and\u00a0<\/span><span data-contrast=\"auto\">4<\/span><span data-contrast=\"auto\">% of staff tested positive.\u00a0<\/span><span data-contrast=\"auto\">Of those without symptoms,\u00a0<\/span><span data-contrast=\"auto\">1<\/span><span data-contrast=\"auto\">3<\/span><span data-contrast=\"auto\">% of residents and\u00a0<\/span><span data-contrast=\"auto\">4<\/span><span data-contrast=\"auto\">% of staff tested positive<\/span><span data-contrast=\"auto\">, compared to 53<\/span><span data-contrast=\"auto\">% of residents and 18% of staff with symptoms.<\/span><span data-contrast=\"auto\">\u00a0<\/span><span data-contrast=\"auto\">There was<\/span><span data-contrast=\"auto\">\u00a0<\/span><span data-contrast=\"auto\">a statistical<\/span><span data-contrast=\"auto\">,<\/span><span data-contrast=\"auto\">\u00a0<\/span><span data-contrast=\"auto\">though not\u00a0<\/span><span data-contrast=\"auto\">meaningful<\/span><span data-contrast=\"auto\">,<\/span><span data-contrast=\"auto\">\u00a0<\/span><span data-contrast=\"auto\">differe<\/span><span data-contrast=\"auto\">nce<\/span><span data-contrast=\"auto\">\u00a0<\/span><span data-contrast=\"auto\">in\u00a0<\/span><span data-contrast=\"auto\">viral load<\/span><span data-contrast=\"auto\">s<\/span><span data-contrast=\"auto\">\u00a0<\/span><span data-contrast=\"auto\">between\u00a0<\/span><span data-contrast=\"auto\">patients with and without symptoms (mean<\/span><span data-contrast=\"auto\">\u00a0differenc<\/span><span data-contrast=\"auto\">e<\/span><span data-contrast=\"auto\">=<\/span><span data-contrast=\"auto\">0.71 cycles, p=0.006).<\/span><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li>\n<\/ul>\n<p><i><span data-contrast=\"none\">Lennon et al. (July 26, 2020). Comparison of Viral Levels in Individuals with or without Symptoms at Time of COVID-19 Testing among 32480 Residents and Staff of Nursing Homes and Assisted Living Facilities in Massachusetts.\u00a0<\/span><\/i><i><span data-contrast=\"none\">Pre-print downloaded July 27 from<\/span><\/i><i><span data-contrast=\"none\">\u00a0<\/span><\/i><a href=\"https:\/\/doi.org\/10.1101\/2020.07.20.20157792\"><span data-contrast=\"none\">https:\/\/doi.org\/10.1101\/2020.07.20.20157792<\/span><\/a><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559685&quot;:720,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/p>\n<\/p>\n<\/div>\n<p>\t\t\t\t\t\t\t\t\t<!-- <a href=\"\" class=\"su-post-comments-link\"><\/a> --><\/p>\n<\/div>\n<div id=\"su-post-8498\" class=\"su-post\">\n<h5 class=\"su-post-title\">Hydroxychloroquine with or without Azithromycin in Mild-to-Moderate Covid-19<\/h5>\n<p>\t\t\t\t<!-- \n\n\n\n\n\n\n\n\n\n\n\n<div class=\"su-post-meta\">\n\t\t\t\t\t: \t\t\t\t<\/div>\n\n\n\n\n\n\n\n\n\n\n\n --><\/p>\n<div class=\"su-post-excerpt\">\n<ul>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"34\" data-aria-posinset=\"2019\" data-aria-level=\"1\"><span data-contrast=\"auto\">A randomized trial of hydroxychloroquine, alone or with a<\/span><span data-contrast=\"auto\">zithromycin<\/span><span data-contrast=\"auto\">,<\/span><span data-contrast=\"auto\">\u00a0<\/span><span data-contrast=\"auto\">for treatment of mild- to moderate COVID-19 found no effect on\u00a0<\/span><span data-contrast=\"auto\">improving clinical status at 15 days after hospital admission<\/span><span data-contrast=\"auto\">.\u00a0<\/span><span data-contrast=\"auto\">Cavalcanti et al. conducted a<\/span><span data-contrast=\"auto\">\u00a0<\/span><span data-contrast=\"auto\">multicenter, randomized, open-label, three-<\/span><span data-contrast=\"auto\">arm<\/span><span data-contrast=\"auto\">\u00a0controlled trial (n=504)<\/span><span data-contrast=\"auto\">\u00a0in Brazil<\/span><span data-contrast=\"auto\">\u00a0<\/span><span data-contrast=\"auto\">and\u00a0<\/span><span data-contrast=\"auto\">found that the odds of having a higher score<\/span><span data-contrast=\"auto\">\u00a0(worse clinical status)<\/span><span data-contrast=\"auto\">\u00a0on\u00a0<\/span><span data-contrast=\"auto\">a\u00a0<\/span><span data-contrast=\"auto\">7-point ordinal scale at 15 days was not affe<\/span><span data-contrast=\"auto\">cted<\/span><span data-contrast=\"auto\">\u00a0by\u00a0<\/span><span data-contrast=\"auto\">hydroxychloroquine\u00a0<\/span><span data-contrast=\"auto\">alone (OR=1.21, 95% CI 0.69-2.11),<\/span><span data-contrast=\"auto\">\u00a0or hydroxychloroquine<\/span><span data-contrast=\"auto\">\u00a0<\/span><span data-contrast=\"auto\">and<\/span><span data-contrast=\"auto\">\u00a0<\/span><span data-contrast=\"auto\">a<\/span><span data-contrast=\"auto\">zithromycin (OR=0.99, 95% CI 0.57-1.73)<\/span><span data-contrast=\"auto\">, compared to standard care<\/span><span data-contrast=\"auto\">.<\/span><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li>\n<\/ul>\n<p><i><span data-contrast=\"none\">Cavalcanti et al. (July 23, 2020). Hydroxychloroquine with or without Azithromycin in Mild-to-Moderate Covid-19. New England Journal of Medicine.\u00a0<\/span><\/i><a href=\"https:\/\/doi.org\/10.1056\/NEJMoa2019014\"><span data-contrast=\"none\">https:\/\/doi.org\/10.1056\/NEJMoa2019014<\/span><\/a><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559685&quot;:720,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/p>\n<\/p>\n<\/div>\n<p>\t\t\t\t\t\t\t\t\t<!-- <a href=\"\" class=\"su-post-comments-link\"><\/a> --><\/p>\n<\/div>\n<div id=\"su-post-8496\" class=\"su-post\">\n<h5 class=\"su-post-title\">Decreasing Median Age of COVID-19 Cases in the United States Changing Epidemiology or Changing Surveillance<\/h5>\n<p>\t\t\t\t<!-- \n\n\n\n\n\n\n\n\n\n\n\n<div class=\"su-post-meta\">\n\t\t\t\t\t: \t\t\t\t<\/div>\n\n\n\n\n\n\n\n\n\n\n\n --><\/p>\n<div class=\"su-post-excerpt\">\n<ul>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"34\" data-aria-posinset=\"2019\" data-aria-level=\"1\"><i><span data-contrast=\"none\">[Pre-print, not peer reviewed]<\/span><\/i><span data-contrast=\"auto\">\u00a0<\/span><span data-contrast=\"auto\">Using PCR test results f<\/span><span data-contrast=\"auto\">ro<\/span><span data-contrast=\"auto\">m a national reference laboratory (n=277,601), Greene et al. compared\u00a0<\/span><span data-contrast=\"auto\">the age distribution<\/span><span data-contrast=\"auto\">\u00a0<\/span><span data-contrast=\"auto\">of<\/span><span data-contrast=\"auto\">\u00a0positiv<\/span><span data-contrast=\"auto\">e<\/span><span data-contrast=\"auto\">\u00a0<\/span><span data-contrast=\"auto\">SARS-CoV-2 test results\u00a0<\/span><span data-contrast=\"auto\">between March-April and June-July and found that the median age of people\u00a0<\/span><span data-contrast=\"auto\">testing positive\u00a0<\/span><span data-contrast=\"auto\">has declined over time from 4<\/span><span data-contrast=\"auto\">1<\/span><span data-contrast=\"auto\">\u00a0years (IQR 29.0-54.1) to 3<\/span><span data-contrast=\"auto\">6<\/span><span data-contrast=\"auto\">\u00a0years (IQR 24.0-50.2).\u00a0<\/span><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"34\" data-aria-posinset=\"2019\" data-aria-level=\"1\"><span data-contrast=\"auto\">A sub-analysis\u00a0<\/span><span data-contrast=\"auto\">showed\u00a0<\/span><span data-contrast=\"auto\">that this trend was only observed for outpatient populations<\/span><span data-contrast=\"auto\">, while the minority of positive tests coming from inpatients (2%) showed an increase in age over time. Additionally, the test positivity rate increased among patients under 50 years old and decreased among patients over 50 years<\/span><span data-contrast=\"auto\">.<\/span><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li>\n<\/ul>\n<p><i><span data-contrast=\"none\">Greene et al. (July 24, 2020). Decreasing Median Age of COVID-19 Cases in the United States Changing Epidemiology or Changing Surveillance.\u00a0<\/span><\/i><i><span data-contrast=\"none\">Pre-print downloaded July 27 from<\/span><\/i><i><span data-contrast=\"none\">\u00a0<\/span><\/i><a href=\"https:\/\/doi.org\/10.1101\/2020.07.22.20160119\"><span data-contrast=\"none\">https:\/\/doi.org\/10.1101\/2020.07.22.20160119<\/span><\/a><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559685&quot;:720,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/p>\n<\/p>\n<\/div>\n<p>\t\t\t\t\t\t\t\t\t<!-- <a href=\"\" class=\"su-post-comments-link\"><\/a> --><\/p>\n<\/div>\n<div id=\"su-post-8494\" class=\"su-post\">\n<h5 class=\"su-post-title\">Systematic SARS-CoV-2 Screening at Hospital Admission in Children:\u00a0A French Prospective Multicenter Study<\/h5>\n<p>\t\t\t\t<!-- \n\n\n\n\n\n\n\n\n\n\n\n<div class=\"su-post-meta\">\n\t\t\t\t\t: \t\t\t\t<\/div>\n\n\n\n\n\n\n\n\n\n\n\n --><\/p>\n<div class=\"su-post-excerpt\">\n<ul>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"34\" data-aria-posinset=\"2019\" data-aria-level=\"1\"><span data-contrast=\"auto\">A prospective multicenter study of pediatric patients in France (n=438) showed that a symptom-based SARS-CoV-2 testing strategy failed to identify 45% (95% CI 24%-68%) of hospitalized SARS-CoV-2 infected children<\/span><span data-contrast=\"auto\">\u00a0at the time of hospital admission<\/span><span data-contrast=\"auto\">.<\/span><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li>\n<\/ul>\n<p><i><span data-contrast=\"none\">Poline et al. (July 25, 2020). Systematic SARS-CoV-2 Screening at Hospital Admission in Children:<\/span><\/i><i><span data-contrast=\"none\">\u00a0<\/span><\/i><i><span data-contrast=\"none\">A French Prospective Multicenter Study. Clinical Infectious Diseases.\u00a0<\/span><\/i><a href=\"https:\/\/doi.org\/10.1093\/cid\/ciaa1044\"><span data-contrast=\"none\">https:\/\/doi.org\/10.1093\/cid\/ciaa1044<\/span><\/a><i><span data-contrast=\"none\">\u00a0<\/span><\/i><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559685&quot;:720,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/p>\n<\/p>\n<\/div>\n<p>\t\t\t\t\t\t\t\t\t<!-- <a href=\"\" class=\"su-post-comments-link\"><\/a> --><\/p>\n<\/div>\n<\/div>\n<\/div>\n<div class=\"js-accordion__panel\" >\n<h2 class=\"js-accordion__header\"><span class=\"TextRun SCXW45500551 BCX0\" lang=\"EN-US\" xml:lang=\"EN-US\" data-contrast=\"none\"><span class=\"NormalTextRun SCXW45500551 BCX0\" data-ccp-parastyle=\"heading 2\">Mental Health and Personal Impact<\/span><\/span><\/h2>\n<div class=\"su-posts su-posts-default-loop\">\n<div id=\"su-post-8510\" class=\"su-post\">\n<h5 class=\"su-post-title\">Well-Being of Parents and Children During the COVID-19 Pandemic: A National Survey<\/h5>\n<p>\t\t\t\t<!-- \n\n\n\n\n\n\n\n\n\n\n\n<div class=\"su-post-meta\">\n\t\t\t\t\t: \t\t\t\t<\/div>\n\n\n\n\n\n\n\n\n\n\n\n --><\/p>\n<div class=\"su-post-excerpt\">\n<ul>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"34\" data-aria-posinset=\"2019\" data-aria-level=\"1\"><span data-contrast=\"auto\">A survey of\u00a0<\/span><span data-contrast=\"auto\">a<\/span><span data-contrast=\"auto\">\u00a0national sample of US parents with at least 1 child younger than 18 (n=1,011)\u00a0<\/span><span data-contrast=\"auto\">found that<\/span><span data-contrast=\"auto\">\u00a0<\/span><span data-contrast=\"auto\">27% of parents report<\/span><span data-contrast=\"auto\">ed<\/span><span data-contrast=\"auto\">\u00a0worsening mental health for themselves, 14% report<\/span><span data-contrast=\"auto\">ed<\/span><span data-contrast=\"auto\">\u00a0worsening behavioral health for their children,\u00a0<\/span><span data-contrast=\"auto\">and<\/span><span data-contrast=\"auto\">\u00a0<\/span><span data-contrast=\"auto\">nearly 1 in 10 experienc<\/span><span data-contrast=\"auto\">ed<\/span><span data-contrast=\"auto\">\u00a0both. A decrease in food security, employer-sponsored insurance, and regular childcare were also reported.<\/span><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li>\n<\/ul>\n<p><i><span data-contrast=\"none\">Patrick et al. (July 24, 2020). Well-Being of Parents and Children During the COVID-19 Pandemic: A National Survey. Pediatrics.\u00a0<\/span><\/i><a href=\"https:\/\/doi.org\/10.1542\/peds.2020-016824\"><span data-contrast=\"none\">https:\/\/doi.org\/10.1542\/peds.2020-016824<\/span><\/a><i><span data-contrast=\"none\">\u00a0<\/span><\/i><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559685&quot;:720,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/p>\n<\/p>\n<\/div>\n<p>\t\t\t\t\t\t\t\t\t<!-- <a href=\"\" class=\"su-post-comments-link\"><\/a> --><\/p>\n<\/div>\n<div id=\"su-post-8508\" class=\"su-post\">\n<h5 class=\"su-post-title\">Google Searches for Suicide and Suicide Risk Factors in the Early Stages of the COVID-19 Pandemic<\/h5>\n<p>\t\t\t\t<!-- \n\n\n\n\n\n\n\n\n\n\n\n<div class=\"su-post-meta\">\n\t\t\t\t\t: \t\t\t\t<\/div>\n\n\n\n\n\n\n\n\n\n\n\n --><\/p>\n<div class=\"su-post-excerpt\">\n<ul>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"34\" data-aria-posinset=\"2019\" data-aria-level=\"1\"><span data-contrast=\"auto\">Halford et al. analyzed Google Trends data (March-April) representing searches in the US for terms related to suicide and known suicide risk factors and found that<\/span><span data-contrast=\"auto\">,<\/span><span data-contrast=\"auto\">\u00a0while the proportion of suicide-related queries was lower than expected, queries representative of financial difficulty, help-seeking, and general mental health concerns were elevated, suggesting that the COVID-19 pandemic may have caused an increase in suicide risk factors.<\/span><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li>\n<\/ul>\n<p><i><span data-contrast=\"none\">Halford et al. (July 24, 2020). Google Searches for Suicide and Suicide Risk Factors in the Early Stages of the COVID-19 Pandemic. PLOS ONE.\u00a0<\/span><\/i><a href=\"https:\/\/doi.org\/10.1371\/journal.pone.0236777\"><span data-contrast=\"none\">https:\/\/doi.org\/10.1371\/journal.pone.0236777<\/span><\/a><i><span data-contrast=\"none\">\u00a0<\/span><\/i><\/p>\n<\/p>\n<\/div>\n<p>\t\t\t\t\t\t\t\t\t<!-- <a href=\"\" class=\"su-post-comments-link\"><\/a> --><\/p>\n<\/div>\n<\/div>\n<\/div>\n<div class=\"js-accordion__panel\" >\n<h2 class=\"js-accordion__header\"><span class=\"TextRun SCXW82890009 BCX0\" lang=\"EN-US\" xml:lang=\"EN-US\" data-contrast=\"none\"><span class=\"NormalTextRun SCXW82890009 BCX0\" data-ccp-parastyle=\"heading 2\">Mode<\/span><\/span><span class=\"TextRun SCXW82890009 BCX0\" lang=\"EN-US\" xml:lang=\"EN-US\" data-contrast=\"none\"><span class=\"NormalTextRun SCXW82890009 BCX0\" data-ccp-parastyle=\"heading 2\">ling and Prediction<\/span><\/span><\/h2>\n<div class=\"su-posts su-posts-default-loop\">\n<div id=\"su-post-8512\" class=\"su-post\">\n<h5 class=\"su-post-title\">Simulating the Effect of School Closure during\u00a0COVID-19 Outbreaks in Ontario, Canada<\/h5>\n<p>\t\t\t\t<!-- \n\n\n\n\n\n\n\n\n\n\n\n<div class=\"su-post-meta\">\n\t\t\t\t\t: \t\t\t\t<\/div>\n\n\n\n\n\n\n\n\n\n\n\n --><\/p>\n<div class=\"su-post-excerpt\">\n<ul>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"34\" data-aria-posinset=\"2019\" data-aria-level=\"1\"><span data-contrast=\"auto\">Using an age-structured agent-based model parametrized with demographics from Ontario, C<\/span><span data-contrast=\"auto\">anada<\/span><span data-contrast=\"auto\">, Abdollahi et al<\/span><span data-contrast=\"auto\">.<\/span><span data-contrast=\"auto\">\u00a0found that increasing the duration of school closures from 3 to 16 weeks reduced the COVID-19 attack rate by 7%-1<\/span><span data-contrast=\"auto\">3<\/span><span data-contrast=\"auto\">% when contacts among school children were restricted by 60-80%. Adding varying degrees of voluntary social isolation among mildly symptomatic persons further reduced the attack rate.<\/span><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li>\n<\/ul>\n<p><i><span data-contrast=\"none\">Abdollahi et al. (July 24, 2020). Simulating the Effect of School Closure during\u00a0COVID-19 Outbreaks in Ontario, Canada. BMC Medicine.\u00a0<\/span><\/i><a href=\"https:\/\/doi.org\/10.1186\/s12916-020-01705-8\"><span data-contrast=\"none\">https:\/\/doi.org\/10.1186\/s12916-020-01705-8<\/span><\/a><i><span data-contrast=\"none\">\u00a0<\/span><\/i><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559685&quot;:720,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/p>\n<\/p>\n<\/div>\n<p>\t\t\t\t\t\t\t\t\t<!-- <a href=\"\" class=\"su-post-comments-link\"><\/a> --><\/p>\n<\/div>\n<\/div>\n<\/div>\n<div class=\"js-accordion__panel\" >\n<h2 class=\"js-accordion__header\"><span class=\"TextRun SCXW256833614 BCX0\" lang=\"EN-US\" xml:lang=\"EN-US\" data-contrast=\"none\"><span class=\"NormalTextRun SCXW256833614 BCX0\" data-ccp-parastyle=\"heading 2\">Public Health Policy and Practice<\/span><\/span><\/h2>\n<div class=\"su-posts su-posts-default-loop\">\n<div id=\"su-post-8516\" class=\"su-post\">\n<h5 class=\"su-post-title\">Willingness to Seek Diagnostic Testing for SARS-CoV-2 With Home, Drive-through, and Clinic-Based Specimen Collection Locations<\/h5>\n<p>\t\t\t\t<!-- \n\n\n\n\n\n\n\n\n\n\n\n<div class=\"su-post-meta\">\n\t\t\t\t\t: \t\t\t\t<\/div>\n\n\n\n\n\n\n\n\n\n\n\n --><\/p>\n<div class=\"su-post-excerpt\">\n<ul>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"34\" data-aria-posinset=\"2019\" data-aria-level=\"1\"><span data-contrast=\"auto\">Seigler et al.\u00a0<\/span><span data-contrast=\"auto\">observed that\u00a0<\/span><span data-contrast=\"auto\">participants s<\/span><span data-contrast=\"auto\">urveyed<\/span><span data-contrast=\"auto\">\u00a0using social media (n=1,435)<\/span><span data-contrast=\"auto\">\u00a0were most willing to test for SARS-CoV-2<\/span><span data-contrast=\"auto\">\u00a0infection<\/span><span data-contrast=\"auto\">\u00a0<\/span><span data-contrast=\"auto\">with a home saliva specimen<\/span><span data-contrast=\"auto\">\u00a0(92%)<\/span><span data-contrast=\"auto\">,\u00a0<\/span><span data-contrast=\"none\">followed by<\/span><span data-contrast=\"none\">\u00a0home swab<\/span><span data-contrast=\"none\">\u00a0(88%)<\/span><span data-contrast=\"none\">,\u00a0<\/span><span data-contrast=\"none\">drive-through swab<\/span><span data-contrast=\"none\">\u00a0(71%)<\/span><span data-contrast=\"none\">, and clinic-collected swab<\/span><span data-contrast=\"none\">\u00a0(<\/span><span data-contrast=\"none\">60%)<\/span><span data-contrast=\"auto\">.\u00a0<\/span><span data-contrast=\"auto\">Additionally,\u00a0<\/span><span data-contrast=\"auto\">68% of participants indicated they would be more likely to get tested if there was a home testing option.<\/span><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li>\n<\/ul>\n<p><i><span data-contrast=\"none\">Siegler et al. (June 30, 2020). Willingness to Seek Diagnostic Testing for SARS-CoV-2 With Home, Drive-through, and Clinic-Based Specimen Collection Locations. Open\u00a0Forum\u00a0Infectious Diseases.\u00a0<\/span><\/i><a href=\"https:\/\/doi.org\/10.1093\/ofid\/ofaa269\"><span data-contrast=\"none\">https:\/\/doi.org\/10.1093\/ofid\/ofaa269<\/span><\/a><i><span data-contrast=\"none\">\u00a0<\/span><\/i><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559685&quot;:720,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/p>\n<\/p>\n<\/div>\n<p>\t\t\t\t\t\t\t\t\t<!-- <a href=\"\" class=\"su-post-comments-link\"><\/a> --><\/p>\n<\/div>\n<div id=\"su-post-8514\" class=\"su-post\">\n<h5 class=\"su-post-title\">Risk for COVID-19 Infection and Death among Latinos in the United States: Examining Heterogeneity in Transmission Dynamics<\/h5>\n<p>\t\t\t\t<!-- \n\n\n\n\n\n\n\n\n\n\n\n<div class=\"su-post-meta\">\n\t\t\t\t\t: \t\t\t\t<\/div>\n\n\n\n\n\n\n\n\n\n\n\n --><\/p>\n<div class=\"su-post-excerpt\">\n<ul>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"34\" data-aria-posinset=\"2019\" data-aria-level=\"1\"><span data-contrast=\"auto\">Rodriguez-Diaz et al. compared counties with\u00a0<\/span><span data-contrast=\"auto\">a greater proportion<\/span><span data-contrast=\"auto\">\u00a0of<\/span><span data-contrast=\"auto\">\u00a0Latino\u00a0<\/span><span data-contrast=\"auto\">residents than the US average (<\/span><span data-contrast=\"auto\">n=<\/span><span data-contrast=\"auto\">443<\/span><span data-contrast=\"auto\">)<\/span><span data-contrast=\"auto\">\u00a0<\/span><span data-contrast=\"auto\">and all other counties\u00a0<\/span><span data-contrast=\"auto\">(n=2700)\u00a0<\/span><span data-contrast=\"auto\">and found that COVID-19 cases were greater in Northeastern and Midwestern Latino counties (<\/span><span data-contrast=\"auto\">RR<\/span><span data-contrast=\"auto\">=<\/span><span data-contrast=\"auto\">1.42 and\u00a0<\/span><span data-contrast=\"auto\">RR<\/span><span data-contrast=\"auto\">=<\/span><span data-contrast=\"auto\">1.70, respectively), while deaths were greater in Midwestern Latino counties (RR, 1.17, 95% CI 1.04-1.34).<\/span><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"34\" data-aria-posinset=\"2019\" data-aria-level=\"1\"><span data-contrast=\"auto\">Factors such as greater monolingual Spanish speakers, employment rates, and less social\u00a0distancing\u00a0were associated with higher diagnostic rates, suggesting that structural factors may cause differences in risk among Latino populations.<\/span><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li>\n<\/ul>\n<p><i><span data-contrast=\"none\">Rodriguez-Diaz et al. (July 23, 2020). Risk for COVID-19 Infection and Death among Latinos in the United States: Examining Heterogeneity in Transmission Dynamics. Annals of Epidemiology.\u00a0<\/span><\/i><a href=\"https:\/\/doi.org\/10.1016\/j.annepidem.2020.07.007\"><span data-contrast=\"none\">https:\/\/doi.org\/10.1016\/j.annepidem.2020.07.007<\/span><\/a><i><span data-contrast=\"none\">\u00a0<\/span><\/i><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559685&quot;:720,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/p>\n<\/p>\n<\/div>\n<p>\t\t\t\t\t\t\t\t\t<!-- <a href=\"\" class=\"su-post-comments-link\"><\/a> --><\/p>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<h3><strong>Other Resources and Commentaries<\/strong><\/h3>\n<ul>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"32\" data-aria-posinset=\"2019\" data-aria-level=\"1\"><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/32703862\/\"><span data-contrast=\"none\">The COVID-19 Pandemic and Human Fertility<\/span><\/a><span data-contrast=\"auto\">\u00a0\u2013 Science<\/span><span data-contrast=\"auto\">\u00a0(<\/span><span data-contrast=\"auto\">July 24)\u00a0<\/span><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"32\" data-aria-posinset=\"2019\" data-aria-level=\"1\"><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/32703870\/\"><span data-contrast=\"none\">A Community-Led Approach to COVID-19<\/span><\/a><span data-contrast=\"auto\">\u00a0\u2013 Science<\/span><span data-contrast=\"auto\">\u00a0(<\/span><span data-contrast=\"auto\">July 24)\u00a0<\/span><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li>\n<\/ul>\n<ul>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"32\" data-aria-posinset=\"2019\" data-aria-level=\"1\"><a href=\"https:\/\/doi.org\/10.1089\/hs.2020.0106\"><span data-contrast=\"none\">A Social and Behavioral Research Agenda to Facilitate COVID-19 Vaccine Uptake in the United States<\/span><\/a><span data-contrast=\"auto\">\u00a0\u2013 Health Security (July 24)\u00a0<\/span><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"32\" data-aria-posinset=\"2019\" data-aria-level=\"1\"><a href=\"https:\/\/doi.org\/10.1016\/S2213-2600(20)30323-4\"><span data-contrast=\"none\">Particle Sizes of Infectious Aerosols: Implications for Infection Control<\/span><\/a><span data-contrast=\"auto\">\u00a0\u2013 The Lancet Respiratory Medicine (July 24)\u00a0<\/span><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"32\" data-aria-posinset=\"2019\" data-aria-level=\"1\"><a href=\"https:\/\/doi.org\/10.1002\/ppul.24981\"><span data-contrast=\"none\">Insight into the Pediatric and Adult Dichotomy of COVID\u201019: Age\u2010Related Differences in the Immune Response to SARS\u2010CoV\u20102 Infection<\/span><\/a><span data-contrast=\"auto\">\u00a0\u2013 Pediatric Pulmonology (July 25)\u00a0<\/span><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"32\" data-aria-posinset=\"2019\" data-aria-level=\"1\"><a href=\"https:\/\/doi.org\/10.1101\/2020.07.19.20157362\"><span data-contrast=\"none\">On the Effect of Age on the Transmission of SARS-CoV-2 in Households Schools and the Community<\/span><\/a><span data-contrast=\"auto\">\u00a0\u2013\u00a0<\/span><span data-contrast=\"auto\">medRxiv<\/span><span data-contrast=\"auto\">\u00a0(July 24)\u00a0<\/span><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"32\" data-aria-posinset=\"2019\" data-aria-level=\"1\"><a href=\"https:\/\/doi.org\/10.1128\/JCM.01416-20\"><span data-contrast=\"none\">The First Quarter of SARS-CoV-2 Testing: The University of Washington Medicine Experience<\/span><\/a><span data-contrast=\"auto\">\u00a0\u2013 Journal of Clinical Microbiology (July 23)\u00a0<\/span><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li>\n<\/ul>\n<ul>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"32\" data-aria-posinset=\"2019\" data-aria-level=\"1\"><a href=\"https:\/\/doi.org\/10.1016\/S0140-6736(20)31636-6\"><span data-contrast=\"none\">Offline: Preparing for a Vaccine against COVID-19<\/span><\/a><span data-contrast=\"auto\">\u00a0\u2013 The Lancet (July 25)\u00a0<\/span><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"32\" data-aria-posinset=\"2019\" data-aria-level=\"1\"><a href=\"https:\/\/doi.org\/10.1056\/NEJMc2025179\"><span data-contrast=\"none\">Rapid Decay of Anti\u2013SARS-CoV-2 Antibodies in Persons with Mild Covid-19<\/span><\/a><span data-contrast=\"auto\">\u00a0\u2013 New England Journal of Medicine (July 21)\u00a0<\/span><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"32\" data-aria-posinset=\"2019\" data-aria-level=\"1\"><a href=\"https:\/\/doi.org\/10.1186\/s12879-020-05281-3\"><span data-contrast=\"none\">Scent Dog Identification of Samples from COVID-19 Patients \u2013 a Pilot Study<\/span><\/a><span data-contrast=\"auto\">\u00a0\u2013 BMC Infectious Diseases (Dec 23)\u00a0<\/span><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"32\" data-aria-posinset=\"2019\" data-aria-level=\"1\"><a href=\"https:\/\/doi.org\/10.1016\/S2215-0366(20)30292-3\"><span data-contrast=\"none\">Disparities in the Recovery from Critical Illness Due to COVID-19<\/span><\/a><span data-contrast=\"auto\">\u00a0\u2013 The Lancet Psychiatry (July 27)\u00a0<\/span><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"32\" data-aria-posinset=\"2019\" data-aria-level=\"1\"><a href=\"https:\/\/doi.org\/10.1126\/science.abd2438\"><span data-contrast=\"none\">Global Quieting of High-Frequency Seismic Noise Due to COVID-19 Pandemic Lockdown Measures<\/span><\/a><span data-contrast=\"auto\">\u00a0\u2013 Science (July 23)\u00a0<\/span><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li>\n<\/ul>\n<ul>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"32\" data-aria-posinset=\"2019\" data-aria-level=\"1\"><a href=\"https:\/\/doi.org\/10.1016\/j.amepre.2020.06.005\"><span data-contrast=\"none\">Disparities in COVID-19 Testing and Positivity in New York City<\/span><\/a><span data-contrast=\"auto\">\u00a0\u2013 American Journal of Preventive Medicine (June 25)\u00a0<\/span><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"32\" data-aria-posinset=\"2019\" data-aria-level=\"1\"><a href=\"https:\/\/doi.org\/10.1101\/2020.07.23.20160788\"><span data-contrast=\"none\">A Framework for SARS-CoV-2 Testing on a Large University Campus Statistical Considerations<\/span><\/a><span data-contrast=\"auto\">\u00a0\u2013\u00a0<\/span><span data-contrast=\"auto\">medRxiv<\/span><span data-contrast=\"auto\">\u00a0(July 24)\u00a0<\/span><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"32\" data-aria-posinset=\"2019\" data-aria-level=\"1\"><a href=\"https:\/\/doi.org\/10.1016\/S2468-2667(20)30161-4\"><span data-contrast=\"none\">Disability and COVID-19: Who Counts Depends on Who Is Counted<\/span><\/a><span data-contrast=\"auto\">\u00a0\u2013\u00a0The Lancet\u00a0Public Health\u00a0<\/span><br \/>\n<span data-contrast=\"auto\">(July 21)\u00a0<\/span><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"32\" data-aria-posinset=\"2019\" data-aria-level=\"1\"><a href=\"https:\/\/doi.org\/10.1016\/j.scitotenv.2020.141022\"><span data-contrast=\"none\">COVID-19 and the Environment: A Critical Review and Research Agenda<\/span><\/a><span data-contrast=\"auto\">\u00a0\u2013 Science of The Total Environment (<\/span><span data-contrast=\"auto\">July<\/span><span data-contrast=\"auto\">\u00a017)\u00a0<\/span><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"32\" data-aria-posinset=\"2019\" data-aria-level=\"1\"><a href=\"https:\/\/doi.org\/10.1056\/NEJMsr2022263\"><span data-contrast=\"none\">Rapid Scaling Up of Covid-19 Diagnostic Testing in the United States \u2014 The NIH RADx Initiative<\/span><\/a><span data-contrast=\"auto\">\u00a0\u2013 New England Journal of Medicine (July 22)\u00a0<\/span><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li>\n<\/ul>\n<ul>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"32\" data-aria-posinset=\"2019\" data-aria-level=\"1\"><a href=\"https:\/\/doi.org\/10.1007\/s40291-020-00486-3\"><span data-contrast=\"none\">Preliminary Analysis of B- and T-Cell Responses to SARS-CoV-2<\/span><\/a><span data-contrast=\"auto\">\u00a0\u2013 Molecular Diagnosis &amp; Therapy\u00a0<\/span><br \/>\n<span data-contrast=\"auto\">(July 24)\u00a0<\/span><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"32\" data-aria-posinset=\"2019\" data-aria-level=\"1\"><a href=\"https:\/\/doi.org\/10.1016\/S1473-3099(20)30458-8\"><span data-contrast=\"none\">Monitoring Approaches for Health-Care Workers during the COVID-19 Pandemic<\/span><\/a><span data-contrast=\"auto\">\u00a0\u2013\u00a0The Lancet\u00a0Infectious Diseases (July 23)\u00a0<\/span><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li>\n<\/ul>\n","protected":false},"excerpt":{"rendered":"<p>Analysis of PCR test results from a national reference laboratory found that the median age of people testing positive for SARS-CoV-2 in the US has declined from 41 years in April-May to 36 years in June-July. <\/p>\n<div><a class=\"more\" href=\"https:\/\/depts.washington.edu\/pandemicalliance\/2020\/07\/27\/risk-for-covid-19-infection-and-death-among-latinos-in-the-united-states-examining-heterogeneity-in-transmission-dynamics\/\">Read more<\/a><\/div>\n","protected":false},"author":8,"featured_media":6960,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":"","_links_to":"","_links_to_target":""},"categories":[5],"tags":[],"topic":[],"class_list":["post-8492","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-covid-19-literature-situation-report"],"_links":{"self":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/8492","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/users\/8"}],"replies":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/comments?post=8492"}],"version-history":[{"count":1,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/8492\/revisions"}],"predecessor-version":[{"id":8518,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/8492\/revisions\/8518"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/media\/6960"}],"wp:attachment":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/media?parent=8492"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/categories?post=8492"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/tags?post=8492"},{"taxonomy":"topic","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/topic?post=8492"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}