{"id":8519,"date":"2020-07-28T10:36:01","date_gmt":"2020-07-28T17:36:01","guid":{"rendered":"https:\/\/depts.washington.edu\/pandemicalliance\/?p=8519"},"modified":"2021-04-05T10:48:36","modified_gmt":"2021-04-05T17:48:36","slug":"covid-19-literature-situation-report-july-28-2020","status":"publish","type":"post","link":"https:\/\/depts.washington.edu\/pandemicalliance\/2020\/07\/28\/covid-19-literature-situation-report-july-28-2020\/","title":{"rendered":"COVID-19 Literature Situation Report July 28, 2020"},"content":{"rendered":"<p>The scientific literature on COVID-19 is rapidly evolving and these articles were selected for review based on their relevance to Washington State decision making around COVID-19 response efforts. Included in these Lit Reps are some manuscripts that have been made available online as pre-prints but have not yet undergone peer review. Please be aware of this when reviewing articles included in the Lit Reps.<\/p>\n<h2>Key Takeaways<\/h2>\n<ul>\n<li><b><span data-contrast=\"auto\">SARS-CoV-2 testing\u00a0<\/span><\/b><b><span data-contrast=\"auto\">among household contacts of\u00a0<\/span><\/b><b><span data-contrast=\"auto\">COVID-19 cases in Wisconsin and Utah found\u00a0<\/span><\/b><b><span data-contrast=\"auto\">a<\/span><\/b><b><span data-contrast=\"auto\">\u00a020%<\/span><\/b><b><span data-contrast=\"auto\">\u00a0attac<\/span><\/b><b><span data-contrast=\"auto\">k<\/span><\/b><b><span data-contrast=\"auto\">\u00a0rate<\/span><\/b><b><span data-contrast=\"auto\">\u00a0among contacts under age 18 years and 26% among those 18 years or older.<\/span><\/b><a href=\"https:\/\/doi.org\/10.1093\/cid\/ciaa1072\"><span data-contrast=\"none\">\u00a0More<\/span><\/a><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li>\n<li data-leveltext=\"\uf0d8\" data-font=\"Wingdings\" data-listid=\"1\" data-aria-posinset=\"1\" data-aria-level=\"1\"><b><span data-contrast=\"auto\">A UK modeling study using pre<\/span><\/b><b><span data-contrast=\"auto\">-existing<\/span><\/b><b><span data-contrast=\"auto\">\u00a0contact<\/span><\/b><b><span data-contrast=\"auto\">\u00a0and post-lockdown mobility<\/span><\/b><b><span data-contrast=\"auto\">\u00a0data found that<\/span><\/b><b><span data-contrast=\"auto\">,<\/span><\/b><b><span data-contrast=\"auto\">\u00a0in a scenario in which\u00a0<\/span><\/b><b><span data-contrast=\"auto\">all children return to\u00a0<\/span><\/b><b><span data-contrast=\"auto\">elementary\u00a0<\/span><\/b><b><span data-contrast=\"auto\">school<\/span><\/b><b><span data-contrast=\"auto\">, R<\/span><\/b><b><span data-contrast=\"auto\">0<\/span><\/b><b><span data-contrast=\"auto\">\u00a0<\/span><\/b><b><span data-contrast=\"auto\">remains below 1 only if<\/span><\/b><b><span data-contrast=\"auto\">\u00a0non-household contacts remain low or\u00a0<\/span><\/b><b><span data-contrast=\"auto\">a high proportion of contacts can be traced and self-isolate.<\/span><\/b><span data-contrast=\"auto\">\u00a0<\/span><a href=\"https:\/\/doi.org\/10.1101\/2020.07.25.20156471\"><span data-contrast=\"none\">More<\/span><\/a><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li>\n<li data-leveltext=\"\uf0d8\" data-font=\"Wingdings\" data-listid=\"1\" data-aria-posinset=\"2\" data-aria-level=\"1\"><b><span data-contrast=\"auto\">Surveillance\u00a0<\/span><\/b><b><span data-contrast=\"auto\">testing by RT-PCR\u00a0<\/span><\/b><b><span data-contrast=\"auto\">of asymptomatic healthcare workers<\/span><\/b><b><span data-contrast=\"auto\">\u00a0<\/span><\/b><b><span data-contrast=\"auto\">in greater Houston\u00a0<\/span><\/b><b><span data-contrast=\"auto\">(<\/span><\/b><b><span data-contrast=\"auto\">March and April<\/span><\/b><b><span data-contrast=\"auto\">)<\/span><\/b><b><span data-contrast=\"auto\">\u00a0found\u00a0<\/span><\/b><b><span data-contrast=\"auto\">a SARS-CoV-2 prevalence of\u00a0<\/span><\/b><b><span data-contrast=\"auto\">5% among those from COVID-19 units versus 0.6%\u00a0<\/span><\/b><b><span data-contrast=\"auto\">among those\u00a0<\/span><\/b><b><span data-contrast=\"auto\">from non-COVID units<\/span><\/b><b><span data-contrast=\"auto\">.<\/span><\/b><b><span data-contrast=\"auto\">\u00a0<\/span><\/b><a href=\"https:\/\/doi.org\/10.1001\/jamanetworkopen.2020.16451\"><span data-contrast=\"none\">More<\/span><\/a><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li>\n<\/ul>\n<div id=\"uw-accordion-shortcode\">\n<h3>Article Summaries<\/h3>\n<div class=\"js-accordion\" data-accordion-prefix-classes=\"uw-accordion-shortcode\">\n<div class=\"js-accordion__panel\" >\n<h2 class=\"js-accordion__header\"><span class=\"TextRun SCXW70641427 BCX0\" lang=\"EN-US\" xml:lang=\"EN-US\" data-contrast=\"none\"><span class=\"NormalTextRun SCXW70641427 BCX0\" data-ccp-parastyle=\"heading 2\">Transmission<\/span><\/span><\/h2>\n<div class=\"su-posts su-posts-default-loop\">\n<div id=\"su-post-8525\" class=\"su-post\">\n<h5 class=\"su-post-title\">Estimation of Viral Aerosol Emissions\u00a0From\u00a0Simulated Individuals\u00a0With\u00a0Asymptomatic to Moderate Coronavirus Disease 2019<\/h5>\n<p>\t\t\t\t<!-- \n\n\n\n\n\n\n\n\n\n\n\n<div class=\"su-post-meta\">\n\t\t\t\t\t: \t\t\t\t<\/div>\n\n\n\n\n\n\n\n\n\n\n\n --><\/p>\n<div class=\"su-post-excerpt\">\n<ul>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"50\" data-aria-posinset=\"1\" data-aria-level=\"1\"><span data-contrast=\"auto\">A model<\/span><span data-contrast=\"auto\">ing study<\/span><span data-contrast=\"auto\">\u00a0indicated that\u00a0<\/span><span data-contrast=\"auto\">an individual with COVID-19 who is\u00a0<\/span><span data-contrast=\"auto\">coughing\u00a0<\/span><span data-contrast=\"auto\">or\u00a0<\/span><span data-contrast=\"auto\">breathing normally release<\/span><span data-contrast=\"auto\">s<\/span><span data-contrast=\"auto\">\u00a0large numbers of viruses,\u00a0<\/span><span data-contrast=\"auto\">but\u00a0<\/span><span data-contrast=\"auto\">the estimated infectious risk from an individual with\u00a0<\/span><span data-contrast=\"auto\">a\u00a0<\/span><span data-contrast=\"auto\">typical viral load\u00a0<\/span><span data-contrast=\"auto\">in a space the\u00a0<\/span><span data-contrast=\"auto\">size of a medical<\/span><span data-contrast=\"auto\">\u00a0exam room<\/span><span data-contrast=\"auto\">\u00a0<\/span><span data-contrast=\"auto\">was low.\u00a0<\/span><span data-contrast=\"auto\">Riediker\u00a0and Tsai simulated the release of viruses from individuals with asymptomatic to moderate COVID-1<\/span><span data-contrast=\"auto\">9<\/span><span data-contrast=\"auto\">\u00a0infection during normal breathing and while coughing.<\/span><span data-contrast=\"auto\">\u00a0<\/span><span data-contrast=\"auto\">Viral loads across different droplet sizes produced under various conditions\u00a0<\/span><span data-contrast=\"auto\">were derived from literature<\/span><span data-contrast=\"auto\">.\u00a0<\/span><span data-contrast=\"auto\">The authors applied a compartmental model to estimate virus load in a perfectly mixed 50m<\/span><span data-contrast=\"auto\">3<\/span><span data-contrast=\"auto\">\u00a0room with\u00a0<\/span><span data-contrast=\"auto\">one\u00a0<\/span><span data-contrast=\"auto\">individual as the source, assuming a virus half<\/span><span data-contrast=\"auto\">&#8211;<\/span><span data-contrast=\"auto\">life of 1.1 hours, under normal breathing and with coughing every 30 seconds.\u00a0<\/span><span data-contrast=\"auto\">Concentration plateau<\/span><span data-contrast=\"auto\">ed<\/span><span data-contrast=\"auto\">\u00a0in higher ventilation settings (10 exchanges\/hour) after 30 minutes, versus 70 minutes in lower ventilation settings (3 exchanges\/hour).\u00a0<\/span><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li>\n<\/ul>\n<p><i><span data-contrast=\"none\">Riediker\u00a0and Tsai. (July 2020). Estimation of Viral Aerosol Emissions\u00a0From\u00a0Simulated Individuals\u00a0With\u00a0Asymptomatic to Moderate Coronavirus Disease 2019. JAMA Network Open.\u00a0<\/span><\/i><a href=\"https:\/\/doi.org\/10.1001\/jamanetworkopen.2020.13807\"><span data-contrast=\"none\">https:\/\/doi.org\/10.1001\/jamanetworkopen.2020.13807<\/span><\/a><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559685&quot;:720,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/p>\n<\/p>\n<\/div>\n<p>\t\t\t\t\t\t\t\t\t<!-- <a href=\"\" class=\"su-post-comments-link\"><\/a> --><\/p>\n<\/div>\n<div id=\"su-post-8523\" class=\"su-post\">\n<h5 class=\"su-post-title\">Prevalence of SARS-CoV-2 Infection Among Asymptomatic Health Care Workers in\u00a0the Greater\u00a0Houston, Texas, Area<\/h5>\n<p>\t\t\t\t<!-- \n\n\n\n\n\n\n\n\n\n\n\n<div class=\"su-post-meta\">\n\t\t\t\t\t: \t\t\t\t<\/div>\n\n\n\n\n\n\n\n\n\n\n\n --><\/p>\n<div class=\"su-post-excerpt\">\n<ul>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"49\" data-aria-posinset=\"1\" data-aria-level=\"1\"><span data-contrast=\"auto\">A surveillance program among asymptomatic clinical and nonclinical workers at Houston Methodist (an academic medical center with 7 community hospitals), and expanded to asymptomatic community residents, found that out of 2,872 participants (March 11 to April 19) 4% tested positive for SARS-CoV-2<\/span><span data-contrast=\"auto\">\u00a0by RT-PCR<\/span><span data-contrast=\"auto\">, with\u00a0all of\u00a0the positive results being in clinical healthcare workers. Among clinical healthcare workers, prevalence was 5% (95% CI 4.5-6.5%) among those from COVID-19 units versus 0.6% (95% CI 0.2-1.7%) from non-COVID units.\u00a0<\/span><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li>\n<\/ul>\n<p><i><span data-contrast=\"none\">Vahidy\u00a0et al. (July 2020). Prevalence of SARS-CoV-2 Infection Among Asymptomatic Health Care Workers in\u00a0the Greater\u00a0Houston, Texas, Area. JAMA Network Open.\u00a0<\/span><\/i><a href=\"https:\/\/doi.org\/10.1001\/jamanetworkopen.2020.16451\"><span data-contrast=\"none\">https:\/\/doi.org\/10.1001\/jamanetworkopen.2020.16451<\/span><\/a><span data-ccp-props=\"{&quot;201341983&quot;:0,&quot;335559685&quot;:720,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/p>\n<\/p>\n<\/div>\n<p>\t\t\t\t\t\t\t\t\t<!-- <a href=\"\" class=\"su-post-comments-link\"><\/a> --><\/p>\n<\/div>\n<div id=\"su-post-8521\" class=\"su-post\">\n<h5 class=\"su-post-title\">A Prospective Cohort Study in Non-Hospitalized Household Contacts with SARS-CoV-2 Infection: Symptom Profiles and Symptom Change over Time<\/h5>\n<p>\t\t\t\t<!-- \n\n\n\n\n\n\n\n\n\n\n\n<div class=\"su-post-meta\">\n\t\t\t\t\t: \t\t\t\t<\/div>\n\n\n\n\n\n\n\n\n\n\n\n --><\/p>\n<div class=\"su-post-excerpt\">\n<ul>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"50\" data-aria-posinset=\"3\" data-aria-level=\"1\"><span data-contrast=\"auto\">Out of 198 household contacts exposed to SARS-CoV-2 in Wisconsin and Utah and followed longitudinally (PCR two or more times during a\u00a014 day\u00a0period) from March 22 to April 22, 47 were positive by PCR, representing an attack rate of 24%. Among children under 18 years, the attack rate was 20%, versus 26% for adults 18 years or older. While symptom distribution varied\u00a0<\/span><span data-contrast=\"auto\">by\u00a0<\/span><span data-contrast=\"auto\">age, upper respiratory (68%) and neurological (64%) symptoms were the most common, while fever was not commonly reported (19%).\u00a0<\/span><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li>\n<\/ul>\n<p><i><span data-contrast=\"none\">Yousaf et al. (July 2020). A Prospective Cohort Study in Non-Hospitalized Household Contacts with SARS-CoV-2 Infection: Symptom Profiles and Symptom Change over Time. Clinical Infectious Diseases.\u00a0<\/span><\/i><a href=\"https:\/\/doi.org\/10.1093\/cid\/ciaa1072\"><span data-contrast=\"none\">https:\/\/doi.org\/10.1093\/cid\/ciaa1072<\/span><\/a><span data-ccp-props=\"{&quot;201341983&quot;:0,&quot;335559685&quot;:720,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/p>\n<\/p>\n<\/div>\n<p>\t\t\t\t\t\t\t\t\t<!-- <a href=\"\" class=\"su-post-comments-link\"><\/a> --><\/p>\n<\/div>\n<\/div>\n<\/div>\n<div class=\"js-accordion__panel\" >\n<h2 class=\"js-accordion__header\"><span class=\"TextRun SCXW22351167 BCX0\" lang=\"EN-US\" xml:lang=\"EN-US\" data-contrast=\"none\"><span class=\"NormalTextRun SCXW22351167 BCX0\" data-ccp-parastyle=\"heading 2\">Clinical Characteristics<\/span><\/span><span class=\"TextRun SCXW22351167 BCX0\" lang=\"EN-US\" xml:lang=\"EN-US\" data-contrast=\"none\"><span class=\"NormalTextRun SCXW22351167 BCX0\" data-ccp-parastyle=\"heading 2\"> and Health Care Setting<\/span><\/span><\/h2>\n<div class=\"su-posts su-posts-default-loop\">\n<div id=\"su-post-8531\" class=\"su-post\">\n<h5 class=\"su-post-title\">Evolution of Viral\u00a0Quasispecies\u00a0during\u00a0SARS-CoV-2 Infection<\/h5>\n<p>\t\t\t\t<!-- \n\n\n\n\n\n\n\n\n\n\n\n<div class=\"su-post-meta\">\n\t\t\t\t\t: \t\t\t\t<\/div>\n\n\n\n\n\n\n\n\n\n\n\n --><\/p>\n<div class=\"su-post-excerpt\">\n<ul>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"48\" data-aria-posinset=\"1\" data-aria-level=\"1\"><span data-contrast=\"auto\">Jary et al report on\u00a0<\/span><span data-contrast=\"auto\">the genomic diversity of SARS-CoV-2 in longitudinal samples (n=7) collected from a\u00a0<\/span><span data-contrast=\"auto\">single\u00a0<\/span><span data-contrast=\"auto\">patient in\u00a0<\/span><span data-contrast=\"auto\">Paris\u00a0<\/span><span data-contrast=\"auto\">with mild symptoms\u00a0<\/span><span data-contrast=\"auto\">early\u00a0in the course of\u00a0the COVID-19 pandemic.\u00a0<\/span><span data-contrast=\"auto\">Majority consensus\u00a0<\/span><span data-contrast=\"auto\">sequences\u00a0<\/span><span data-contrast=\"auto\">were identical in five out of seven samples<\/span><span data-contrast=\"auto\">, differing from the Wuhan reference sequence by one synonymous mutation.\u00a0<\/span><span data-contrast=\"auto\">Over two hundred<\/span><span data-contrast=\"auto\">\u00a0<\/span><span data-contrast=\"auto\">minority\u00a0<\/span><span data-contrast=\"auto\">variants\u00a0<\/span><span data-contrast=\"auto\">were detected (median of 38 per sample), with four variants shared by different samples<\/span><span data-contrast=\"auto\">.\u00a0<\/span><span data-contrast=\"auto\">Over half\u00a0<\/span><span data-contrast=\"auto\">of mutations had\u00a0moderate\u00a0or high impact on gene expression, and variants differed between lower and upper respiratory tract samples collected on the same day.<\/span><span data-contrast=\"auto\">\u00a0The authors suggest t<\/span><span data-contrast=\"auto\">hese results\u00a0<\/span><span data-contrast=\"auto\">provide evidence of\u00a0<\/span><span data-contrast=\"auto\">SARS-CoV-2\u00a0quasispecies\u00a0<\/span><span data-contrast=\"auto\">that\u00a0<\/span><span data-contrast=\"auto\">vary day-to-day and between anatomical sites.<\/span><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li>\n<\/ul>\n<p><i><span data-contrast=\"none\">Jary et al. (July 2020). Evolution of Viral\u00a0Quasispecies\u00a0during\u00a0SARS-CoV-2 Infection. Clinical Microbiology and Infection.\u00a0<\/span><\/i><a href=\"https:\/\/doi.org\/10.1016\/j.cmi.2020.07.032\"><span data-contrast=\"none\">https:\/\/doi.org\/10.1016\/j.cmi.2020.07.032<\/span><\/a><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559685&quot;:720,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/p>\n<\/p>\n<\/div>\n<p>\t\t\t\t\t\t\t\t\t<!-- <a href=\"\" class=\"su-post-comments-link\"><\/a> --><\/p>\n<\/div>\n<div id=\"su-post-8529\" class=\"su-post\">\n<h5 class=\"su-post-title\">Smell Loss Is a Prognostic Factor for Lower Severity of COVID-19<\/h5>\n<p>\t\t\t\t<!-- \n\n\n\n\n\n\n\n\n\n\n\n<div class=\"su-post-meta\">\n\t\t\t\t\t: \t\t\t\t<\/div>\n\n\n\n\n\n\n\n\n\n\n\n --><\/p>\n<div class=\"su-post-excerpt\">\n<ul>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"46\" data-aria-posinset=\"1\" data-aria-level=\"1\"><span data-contrast=\"auto\">A study of 949 adult patients testing positive for COVID-19 at a university medical center\u00a0<\/span><span data-contrast=\"auto\">(<\/span><span data-contrast=\"auto\">February 1\u00a0<\/span><span data-contrast=\"auto\">to<\/span><span data-contrast=\"auto\">\u00a0April 3<\/span><span data-contrast=\"auto\">)<\/span><span data-contrast=\"auto\">\u00a0found that 2<\/span><span data-contrast=\"auto\">1<\/span><span data-contrast=\"auto\">% reported loss of smell during their initial evaluation<\/span><span data-contrast=\"auto\">. Loss of smell was<\/span><span data-contrast=\"auto\">\u00a0associated with younger age (mean age 46 with smell loss vs 49 without), female gender (6<\/span><span data-contrast=\"auto\">5<\/span><span data-contrast=\"auto\">% vs 5<\/span><span data-contrast=\"auto\">3<\/span><span data-contrast=\"auto\">%), and higher BMI (mean 33.6 vs 31.5). Smell loss was also significantly associated with history of pre-existing smell dysfunction (<\/span><span data-contrast=\"auto\">OR<\/span><span data-contrast=\"auto\">=<\/span><span data-contrast=\"auto\">4.7), allergic rhinitis (<\/span><span data-contrast=\"auto\">OR<\/span><span data-contrast=\"auto\">=<\/span><span data-contrast=\"auto\">1.8) and chronic rhinosinusitis (<\/span><span data-contrast=\"auto\">OR<\/span><span data-contrast=\"auto\">=<\/span><span data-contrast=\"auto\">3.7).<\/span><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"46\" data-aria-posinset=\"2\" data-aria-level=\"1\"><span data-contrast=\"auto\">Smell loss was significantly associated with decreased risk of hospitalization (<\/span><span data-contrast=\"auto\">OR<\/span><span data-contrast=\"auto\">=<\/span><span data-contrast=\"auto\">0.7), ICU admission (<\/span><span data-contrast=\"auto\">OR<\/span><span data-contrast=\"auto\">=<\/span><span data-contrast=\"auto\">0.38), intubation (<\/span><span data-contrast=\"auto\">OR<\/span><span data-contrast=\"auto\">=<\/span><span data-contrast=\"auto\">0.4), and ARDS (<\/span><span data-contrast=\"auto\">OR<\/span><span data-contrast=\"auto\">=<\/span><span data-contrast=\"auto\">0.5) after adjusting for demographics, BMI, allergic rhinitis, and chronic rhinosinusitis.<\/span><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li>\n<\/ul>\n<p><i><span data-contrast=\"none\">Foster et al. (July 2020). Smell Loss Is a Prognostic Factor for Lower Severity of COVID-19. Annals of Allergy, Asthma &amp; Immunology.\u00a0<\/span><\/i><a href=\"https:\/\/doi.org\/10.1016\/j.anai.2020.07.023\"><span data-contrast=\"none\">https:\/\/doi.org\/10.1016\/j.anai.2020.07.023<\/span><\/a><span data-ccp-props=\"{&quot;201341983&quot;:0,&quot;335559685&quot;:720,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/p>\n<\/p>\n<\/div>\n<p>\t\t\t\t\t\t\t\t\t<!-- <a href=\"\" class=\"su-post-comments-link\"><\/a> --><\/p>\n<\/div>\n<div id=\"su-post-8527\" class=\"su-post\">\n<h5 class=\"su-post-title\">Clinical Characteristics of Children With COVID-19: A Meta-Analysis<\/h5>\n<p>\t\t\t\t<!-- \n\n\n\n\n\n\n\n\n\n\n\n<div class=\"su-post-meta\">\n\t\t\t\t\t: \t\t\t\t<\/div>\n\n\n\n\n\n\n\n\n\n\n\n --><\/p>\n<div class=\"su-post-excerpt\">\n<ul>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"46\" data-aria-posinset=\"2\" data-aria-level=\"1\"><span data-contrast=\"auto\">A meta-analysis (14<\/span><span data-contrast=\"auto\">\u00a0studies and 371 patients<\/span><span data-contrast=\"auto\">) of COVID-19 in children found that 17% (95% CI 9-27) are asy<\/span><span data-contrast=\"auto\">m<\/span><span data-contrast=\"auto\">ptomatic\u00a0<\/span><span data-contrast=\"auto\">(<\/span><span data-contrast=\"auto\">fever is the most common symptom<\/span><span data-contrast=\"auto\">)<\/span><span data-contrast=\"auto\">,\u00a0<\/span><span data-contrast=\"auto\">6<\/span><span data-contrast=\"auto\">7<\/span><span data-contrast=\"auto\">% (95%<\/span><span data-contrast=\"auto\">CI<\/span><span data-contrast=\"auto\">\u00a051-8<\/span><span data-contrast=\"auto\">1<\/span><span data-contrast=\"auto\">) were diagnosed with pneumonia,\u00a0<\/span><span data-contrast=\"auto\">and\u00a0<\/span><span data-contrast=\"auto\">incidence\u00a0<\/span><span data-contrast=\"auto\">of severe or critical illness is close to 0% (95% CI 0-1)<\/span><span data-contrast=\"auto\">.\u00a0<\/span><span data-contrast=\"auto\">Of those diagnosed with pneumonia, 5<\/span><span data-contrast=\"auto\">4<\/span><span data-contrast=\"auto\">% (95%CI 38-6<\/span><span data-contrast=\"auto\">9<\/span><span data-contrast=\"auto\">)<\/span><span data-contrast=\"auto\">\u00a0<\/span><span data-contrast=\"auto\">had ground-glass opacities detected on CT scan<\/span><span data-contrast=\"auto\">. An additional\u00a0<\/span><span data-contrast=\"auto\">19% were asymptomatic but had radiological features of pneumonia.\u00a0<\/span><span data-contrast=\"auto\">Most of the\u00a0included studies\u00a0were case reports or case series from China.\u00a0<\/span><span data-contrast=\"auto\">The authors also note this meta-analysis found a higher proportion of asymptomatic children than most studies from the US and Europe<\/span><span data-contrast=\"auto\">, which may reflect differences in testing policies.\u00a0<\/span><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li>\n<\/ul>\n<p><i><span data-contrast=\"none\">Ding et al. (2020). Clinical Characteristics of Children With COVID-19: A Meta-Analysis. Frontiers in Pediatrics.\u00a0<\/span><\/i><a href=\"https:\/\/doi.org\/10.3389\/fped.2020.00431\"><span data-contrast=\"none\">https:\/\/doi.org\/10.3389\/fped.2020.00431<\/span><\/a><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559685&quot;:720,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/p>\n<\/p>\n<\/div>\n<p>\t\t\t\t\t\t\t\t\t<!-- <a href=\"\" class=\"su-post-comments-link\"><\/a> --><\/p>\n<\/div>\n<\/div>\n<\/div>\n<div class=\"js-accordion__panel\" >\n<h2 class=\"js-accordion__header\"><span class=\"TextRun SCXW20832722 BCX0\" lang=\"EN-US\" xml:lang=\"EN-US\" data-contrast=\"none\"><span class=\"NormalTextRun SCXW20832722 BCX0\" data-ccp-parastyle=\"heading 2\">Mental Health and Personal Impact<\/span><\/span><\/h2>\n<div class=\"su-posts su-posts-default-loop\">\n<div id=\"su-post-8533\" class=\"su-post\">\n<h5 class=\"su-post-title\">Sleep of Preschoolers during the Coronavirus Disease 2019 (COVID-19) Outbreak<\/h5>\n<p>\t\t\t\t<!-- \n\n\n\n\n\n\n\n\n\n\n\n<div class=\"su-post-meta\">\n\t\t\t\t\t: \t\t\t\t<\/div>\n\n\n\n\n\n\n\n\n\n\n\n --><\/p>\n<div class=\"su-post-excerpt\">\n<ul>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"48\" data-aria-posinset=\"1\" data-aria-level=\"1\"><span data-contrast=\"auto\">Results of a Children\u2019s Sleep Habit Questionnaire administered to 1,619 caregivers of preschoolers (4-6 years) in China during the COVID-19 pandemic, compared with a\u00a0sociodemographically\u00a0similar sample in 2018, found later bedtimes and wake times<\/span><span data-contrast=\"auto\">\u00a0during the pandemic period<\/span><span data-contrast=\"auto\">, longer nocturnal and shorter nap sleep durations, comparable 24-hr sleep duration, and few<\/span><span data-contrast=\"auto\">e<\/span><span data-contrast=\"auto\">r caregiver-reported sleep disturbances.<\/span><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li>\n<\/ul>\n<p><i><span data-contrast=\"none\">Liu et al. (July 2020). Sleep of Preschoolers during the Coronavirus Disease 2019 (COVID-19) Outbreak. Journal of Sleep Research.\u00a0<\/span><\/i><a href=\"https:\/\/doi.org\/10.1111\/jsr.13142\"><span data-contrast=\"none\">https:\/\/doi.org\/10.1111\/jsr.13142<\/span><\/a><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559685&quot;:720,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/p>\n<\/p>\n<\/div>\n<p>\t\t\t\t\t\t\t\t\t<!-- <a href=\"\" class=\"su-post-comments-link\"><\/a> --><\/p>\n<\/div>\n<\/div>\n<\/div>\n<div class=\"js-accordion__panel\" >\n<h2 class=\"js-accordion__header\"><span class=\"TextRun SCXW82890009 BCX0\" lang=\"EN-US\" xml:lang=\"EN-US\" data-contrast=\"none\"><span class=\"NormalTextRun SCXW82890009 BCX0\" data-ccp-parastyle=\"heading 2\">Mode<\/span><\/span><span class=\"TextRun SCXW82890009 BCX0\" lang=\"EN-US\" xml:lang=\"EN-US\" data-contrast=\"none\"><span class=\"NormalTextRun SCXW82890009 BCX0\" data-ccp-parastyle=\"heading 2\">ling and Prediction<\/span><\/span><\/h2>\n<div class=\"su-posts su-posts-default-loop\">\n<div id=\"su-post-8535\" class=\"su-post\">\n<h5 class=\"su-post-title\">Using Social Contact Data to Predict and Compare the Impact of Social Distancing Policies with Implications for School Re-Opening<\/h5>\n<p>\t\t\t\t<!-- \n\n\n\n\n\n\n\n\n\n\n\n<div class=\"su-post-meta\">\n\t\t\t\t\t: \t\t\t\t<\/div>\n\n\n\n\n\n\n\n\n\n\n\n --><\/p>\n<div class=\"su-post-excerpt\">\n<ul>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"45\" data-aria-posinset=\"2\" data-aria-level=\"1\"><i><span data-contrast=\"none\">[pre-print, not peer-reviewed]<\/span><\/i><span data-contrast=\"auto\">\u00a0<\/span><span data-contrast=\"auto\">Using UK social contact data collected in 2010<\/span><span data-contrast=\"auto\">\u00a0and Google mobility report data pre- and post-lockdown, Brooks-Pollock\u00a0<\/span><span data-contrast=\"auto\">et al.\u00a0<\/span><span data-contrast=\"auto\">estimated an age-adjusted R<\/span><span data-contrast=\"auto\">0<\/span><span data-contrast=\"auto\">\u00a0for COVID-19 and relative change in\u00a0<\/span><span data-contrast=\"auto\">R<\/span><span data-contrast=\"auto\">0\u00a0<\/span><span data-contrast=\"auto\">in scenarios\u00a0<\/span><span data-contrast=\"auto\">including\u00a0<\/span><span data-contrast=\"auto\">school closures, work closures, and contact tracing<\/span><span data-contrast=\"auto\">. They found<\/span><span data-contrast=\"auto\">\u00a0<\/span><span data-contrast=\"auto\">that<\/span><span data-contrast=\"auto\">\u00a0a<\/span><span data-contrast=\"auto\">\u00a065% reduction in work contacts, a 75% reduction in leisure contacts, and a 95% reduction in school contacts reduces R<\/span><span data-contrast=\"auto\">0<\/span><span data-contrast=\"auto\">\u00a0to 0.7 (95% CI 0.6, 0.8), versus 0.45 (95% CI 0.41, 0.50) when all non-household contacts were eliminated.\u00a0<\/span><span data-contrast=\"auto\">A scenario in which\u00a0<\/span><span data-contrast=\"auto\">all children are back at\u00a0<\/span><span data-contrast=\"auto\">elementary<\/span><span data-contrast=\"auto\">\u00a0school<\/span><span data-contrast=\"auto\">\u00a0resulted in an\u00a0<\/span><span data-contrast=\"auto\">R<\/span><span data-contrast=\"auto\">0<\/span><span data-contrast=\"auto\">\u00a0<\/span><span data-contrast=\"auto\">that\u00a0<\/span><span data-contrast=\"auto\">remains below\u00a0<\/span><span data-contrast=\"auto\">1 only\u00a0<\/span><span data-contrast=\"auto\">if\u00a0<\/span><span data-contrast=\"auto\">non-household contacts\u00a0<\/span><span data-contrast=\"auto\">remain<\/span><span data-contrast=\"auto\">\u00a0<\/span><span data-contrast=\"auto\">l<\/span><span data-contrast=\"auto\">ow<\/span><span data-contrast=\"auto\">, or if a\u00a0<\/span><span data-contrast=\"auto\">high proportion of contacts can be traced and self-isolate.<\/span><span data-contrast=\"auto\">\u00a0<\/span><span data-contrast=\"auto\">\u00a0\u00a0<\/span><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li>\n<\/ul>\n<p><i><span data-contrast=\"none\">Brooks-Pollock et al. (July 27, 2020). Using Social Contact Data to Predict and Compare the Impact of Social Distancing Policies with Implications for School Re-Opening.<\/span><\/i><i><span data-contrast=\"none\">\u00a0Preprint\u00a0downloaded on July 28 from<\/span><\/i><i><span data-contrast=\"none\">\u00a0<\/span><\/i><a href=\"https:\/\/doi.org\/10.1101\/2020.07.25.20156471\"><span data-contrast=\"none\">https:\/\/doi.org\/10.1101\/2020.07.25.20156471<\/span><\/a><span data-ccp-props=\"{&quot;201341983&quot;:0,&quot;335559685&quot;:720,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/p>\n<\/p>\n<\/div>\n<p>\t\t\t\t\t\t\t\t\t<!-- <a href=\"\" class=\"su-post-comments-link\"><\/a> --><\/p>\n<\/div>\n<\/div>\n<\/div>\n<div class=\"js-accordion__panel\" >\n<h2 class=\"js-accordion__header\"><span class=\"TextRun SCXW256833614 BCX0\" lang=\"EN-US\" xml:lang=\"EN-US\" data-contrast=\"none\"><span class=\"NormalTextRun SCXW256833614 BCX0\" data-ccp-parastyle=\"heading 2\">Public Health Policy and Practice<\/span><\/span><\/h2>\n<div class=\"su-posts su-posts-default-loop\">\n<div id=\"su-post-8537\" class=\"su-post\">\n<h5 class=\"su-post-title\">Characteristics and Strength of Evidence of COVID-19 Studies Registered on\u00a0ClinicalTrials.Gov<\/h5>\n<p>\t\t\t\t<!-- \n\n\n\n\n\n\n\n\n\n\n\n<div class=\"su-post-meta\">\n\t\t\t\t\t: \t\t\t\t<\/div>\n\n\n\n\n\n\n\n\n\n\n\n --><\/p>\n<div class=\"su-post-excerpt\">\n<ul>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"49\" data-aria-posinset=\"1\" data-aria-level=\"1\"><span data-contrast=\"auto\">An assessment of COVID-19-related studies registered on ClinicalTrials.gov found that only 29% would have the potential to result in the highest level of individual study evidence (Oxford Centre for Evidence [OCEBM] level 2).\u00a0<\/span><span data-contrast=\"auto\">Pundi\u00a0et al. report on\u00a0<\/span><span data-contrast=\"auto\">COVID-19<\/span><span data-contrast=\"auto\">&#8211;<\/span><span data-contrast=\"auto\">related studies<\/span><span data-contrast=\"auto\">\u00a0registered on ClinicalTrials.gov as<\/span><span data-contrast=\"auto\">\u00a0of\u00a0<\/span><span data-contrast=\"auto\">May 19, 2020, excluding withdrawn, suspended, terminated, or expanded-access studies<\/span><span data-contrast=\"auto\">\u00a0(n=1,551 studies, 911 interventional).\u00a0<\/span><span data-contrast=\"auto\">P<\/span><span data-contrast=\"auto\">rimary outcome pertained to clinical course, including mortality (33%), ventilation requirement (2<\/span><span data-contrast=\"auto\">7<\/span><span data-contrast=\"auto\">%), and treatment complications (23%).\u00a0<\/span><span data-contrast=\"auto\">Of the 664 RCTs, blinding was reported for 55%, placebo control for 29%, planned enrollment of more than 100 participants for 3<\/span><span data-contrast=\"auto\">6<\/span><span data-contrast=\"auto\">%, and two or more study centers for 17%.\u00a0<\/span><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li>\n<\/ul>\n<p><i><span data-contrast=\"none\">Pundi\u00a0et al. (July 27, 2020). Characteristics and Strength of Evidence of COVID-19 Studies Registered on\u00a0ClinicalTrials.Gov. JAMA Internal Medicine.\u00a0<\/span><\/i><a href=\"https:\/\/doi.org\/10.1001\/jamainternmed.2020.2904\"><span data-contrast=\"none\">https:\/\/doi.org\/10.1001\/jamainternmed.2020.2904<\/span><\/a><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559685&quot;:720,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/p>\n<\/p>\n<\/div>\n<p>\t\t\t\t\t\t\t\t\t<!-- <a href=\"\" class=\"su-post-comments-link\"><\/a> --><\/p>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<h3><strong>Other Resources and Commentaries<\/strong><\/h3>\n<ul>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"49\" data-aria-posinset=\"1\" data-aria-level=\"1\"><a href=\"https:\/\/doi.org\/10.1371\/journal.pone.0236554\"><span data-contrast=\"none\">Automated EHR Score to Predict COVID-19 Outcomes at US Department of Veterans Affairs<\/span><\/a><span data-contrast=\"auto\">\u00a0\u2013\u00a0PloS\u00a0One\u00a0<\/span><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"49\" data-aria-posinset=\"2\" data-aria-level=\"1\"><a href=\"https:\/\/doi.org\/10.1016\/S1473-3099(20)30461-8\"><span data-contrast=\"none\">Need for Sustainable Biobanking Networks for COVID-19 and Other Diseases of Epidemic Potential<\/span><\/a><span data-contrast=\"auto\">\u00a0\u2013\u00a0The Lancet<\/span><span data-contrast=\"auto\">\u00a0Infectious Diseases (July\u00a0<\/span><span data-contrast=\"auto\">24<\/span><span data-contrast=\"auto\">)\u00a0<\/span><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"49\" data-aria-posinset=\"3\" data-aria-level=\"1\"><a href=\"https:\/\/doi.org\/10.1016\/j.psychres.2020.113298\"><span data-contrast=\"none\">University Students\u2019 Changes in Mental Health Status and Determinants of Behavior during the COVID-19 Lockdown in Greece<\/span><\/a><span data-contrast=\"auto\">\u00a0\u2013 Psychiatry Research (July)\u00a0<\/span><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li>\n<\/ul>\n<ul>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"49\" data-aria-posinset=\"1\" data-aria-level=\"1\"><a href=\"https:\/\/doi.org\/10.1038\/s41371-020-0387-4\"><span data-contrast=\"none\">Covid-19 and the Cardiovascular System: A Comprehensive Review<\/span><\/a><span data-contrast=\"auto\">\u00a0\u2013 Journal of Human Hypertension (July\u00a0<\/span><span data-contrast=\"auto\">27<\/span><span data-contrast=\"auto\">)\u00a0<\/span><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"49\" data-aria-posinset=\"2\" data-aria-level=\"1\"><a href=\"https:\/\/doi.org\/10.3390\/ijms21155224\"><span data-contrast=\"none\">Potential Anti-COVID-19 Therapeutics That Block the Early Stage of the Viral Life Cycle: Structures, Mechanisms, and Clinical Trials<\/span><\/a><span data-contrast=\"auto\">\u00a0\u2013 International Journal of Molecular Sciences (July\u00a0<\/span><span data-contrast=\"auto\">21<\/span><span data-contrast=\"auto\">)\u00a0<\/span><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"49\" data-aria-posinset=\"3\" data-aria-level=\"1\"><a href=\"https:\/\/doi.org\/10.1016\/j.ebiom.2020.102903\"><span data-contrast=\"none\">SARS-CoV-2 Detection in Different Respiratory Sites: A Systematic Review and Meta-Analysis<\/span><\/a><span data-contrast=\"auto\">\u00a0\u2013\u00a0EBioMedicine\u00a0(July\u00a0<\/span><span data-contrast=\"auto\">24<\/span><span data-contrast=\"auto\">)\u00a0<\/span><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"49\" data-aria-posinset=\"4\" data-aria-level=\"1\"><a href=\"https:\/\/doi.org\/10.1080\/15265161.2020.1779404\"><span data-contrast=\"none\">Maryland\u2019s Experience With the COVID-19 Surge: What Worked, What Didn\u2019t, What Next?<\/span><\/a><span data-contrast=\"auto\">\u00a0\u2013 The American Journal of Bioethics (July 2)\u00a0<\/span><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"49\" data-aria-posinset=\"5\" data-aria-level=\"1\"><a href=\"https:\/\/doi.org\/10.1101\/2020.07.22.20160341\"><span data-contrast=\"none\">Effects of Non-Pharmaceutical Interventions on COVID-19 A Tale of Two Models<\/span><\/a><span data-contrast=\"auto\">\u00a0\u2013\u00a0<\/span><span data-contrast=\"auto\">medRxiv\u00a0<\/span><span data-contrast=\"auto\">(July 27)\u00a0<\/span><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li>\n<\/ul>\n<ul>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"49\" data-aria-posinset=\"1\" data-aria-level=\"1\"><a href=\"https:\/\/doi.org\/10.1101\/2020.07.25.20162107\"><span data-contrast=\"none\">SARS-CoV-2 Viral Load Dynamics Duration of Viral Shedding and Infectiousness a Living Systematic Review and Meta-Analysis<\/span><\/a><span data-contrast=\"auto\">\u00a0\u2013\u00a0<\/span><span data-contrast=\"auto\">m<\/span><span data-contrast=\"auto\">ed<\/span><span data-contrast=\"auto\">R<\/span><span data-contrast=\"auto\">xiv\u00a0(July 28)\u00a0<\/span><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"49\" data-aria-posinset=\"2\" data-aria-level=\"1\"><a href=\"https:\/\/doi.org\/10.1016\/j.drup.2020.100719\"><span data-contrast=\"none\">FDA Approved Drugs with Pharmacotherapeutic Potential for SARS-CoV-2 (COVID-19) Therapy<\/span><\/a><span data-contrast=\"auto\">\u00a0\u2013 Drug Resistance Updates (July)\u00a0<\/span><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"49\" data-aria-posinset=\"3\" data-aria-level=\"1\"><a href=\"https:\/\/doi.org\/10.1080\/15265161.2020.1779403\"><span data-contrast=\"none\">Using a Public Health Ethics Framework to Unpick Discrimination in COVID-19 Responses<\/span><\/a><span data-contrast=\"auto\">\u00a0\u2013 The American Journal of Bioethics (July\u00a0<\/span><span data-contrast=\"auto\">27<\/span><span data-contrast=\"auto\">)\u00a0<\/span><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"49\" data-aria-posinset=\"4\" data-aria-level=\"1\"><a href=\"https:\/\/doi.org\/10.1093\/geronb\/gbaa102\"><span data-contrast=\"none\">From \u201cCoffin Dodger\u201d to \u201cBoomer Remover:\u201d Outbreaks of Ageism in Three Countries with Divergent Approaches to Coronavirus Control<\/span><\/a><span data-contrast=\"auto\">\u00a0\u2013 The Journals of Gerontology (July\u00a0<\/span><span data-contrast=\"auto\">28<\/span><span data-contrast=\"auto\">)\u00a0<\/span><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"49\" data-aria-posinset=\"5\" data-aria-level=\"1\"><a href=\"https:\/\/doi.org\/10.1093\/abm\/kaaa054\"><span data-contrast=\"none\">Latinx Health Disparities Research During COVID-19: Challenges and Innovations<\/span><\/a><span data-contrast=\"auto\">\u00a0\u2013 Annals of Behavioral Medicine (July 27)\u00a0<\/span><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li>\n<\/ul>\n<ul>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"49\" data-aria-posinset=\"1\" data-aria-level=\"1\"><a href=\"https:\/\/doi.org\/10.1038\/s41591-020-1018-x\"><span data-contrast=\"none\">Assessing the Extent of SARS-CoV-2 Circulation through Serological Studies<\/span><\/a><span data-contrast=\"auto\">\u2013 Nature Medicine\u00a0<\/span><br \/>\n<span data-contrast=\"auto\">(July 27)\u00a0<\/span><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"49\" data-aria-posinset=\"2\" data-aria-level=\"1\"><a href=\"https:\/\/doi.org\/10.1080\/15265161.2020.1779396\"><span data-contrast=\"none\">People With Disabilities in COVID-19: Fixing Our Priorities<\/span><\/a><span data-contrast=\"auto\">\u00a0\u2013 The American Journal of Bioethics\u00a0<\/span><br \/>\n<span data-contrast=\"auto\">(July 2)\u00a0<\/span><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"49\" data-aria-posinset=\"3\" data-aria-level=\"1\"><a href=\"https:\/\/doi.org\/10.7326\/M20-4543\"><span data-contrast=\"none\">Occupational Health: A Key to the Control of COVID-19 in Correctional Facilities<\/span><\/a><span data-contrast=\"auto\">\u00a0\u2013 Annals of Internal Medicine (July 27)\u00a0<\/span><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"49\" data-aria-posinset=\"4\" data-aria-level=\"1\"><a href=\"https:\/\/doi.org\/10.3233\/PRM-200722\"><span data-contrast=\"none\">The Actual and Potential Impact of the Novel 2019 Coronavirus on Pediatric Rehabilitation: A Commentary and Review of Its Effects and Potential Disparate Influence on Black, Latinx and Native American Marginalized Populations in the United States<\/span><\/a><span data-contrast=\"auto\">\u00a0\u2013 Journal of Pediatric Rehabilitation Medicine (July )<\/span><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"49\" data-aria-posinset=\"5\" data-aria-level=\"1\"><a href=\"https:\/\/doi.org\/10.1001\/jamainternmed.2020.2926\"><span data-contrast=\"none\">Illness-Related Work Absence in Mid-April Was Highest on Record<\/span><\/a><span data-contrast=\"auto\">\u00a0\u2013 JAMA Internal Medicine (July 27)\u00a0<\/span><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li>\n<\/ul>\n<ul>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"49\" data-aria-posinset=\"1\" data-aria-level=\"1\"><a href=\"https:\/\/doi.org\/10.3389\/fpubh.2020.00358\"><span data-contrast=\"none\">The North American Layman\u2019s Understanding of COVID-19: Are We Doing Enough?<\/span><\/a><span data-contrast=\"auto\">\u00a0\u2013 Frontiers in Public Health<\/span><span data-contrast=\"auto\">\u00a0<\/span><span data-contrast=\"auto\">(July 3, 2020)<\/span><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li>\n<\/ul>\n","protected":false},"excerpt":{"rendered":"<p>SARS-CoV-2 testing among household contacts of COVID-19 cases in Wisconsin and Utah found a 20% attack rate among contacts under age 18 years and 26% among those 18 years or older.<\/p>\n<div><a class=\"more\" href=\"https:\/\/depts.washington.edu\/pandemicalliance\/2020\/07\/28\/characteristics-and-strength-of-evidence-of-covid-19-studies-registered-on-clinicaltrials-gov\/\">Read more<\/a><\/div>\n","protected":false},"author":8,"featured_media":8175,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":"","_links_to":"","_links_to_target":""},"categories":[5],"tags":[],"topic":[],"class_list":["post-8519","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-covid-19-literature-situation-report"],"_links":{"self":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/8519","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/users\/8"}],"replies":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/comments?post=8519"}],"version-history":[{"count":1,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/8519\/revisions"}],"predecessor-version":[{"id":8539,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/8519\/revisions\/8539"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/media\/8175"}],"wp:attachment":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/media?parent=8519"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/categories?post=8519"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/tags?post=8519"},{"taxonomy":"topic","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/topic?post=8519"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}