{"id":8527,"date":"2020-07-28T10:41:09","date_gmt":"2020-07-28T17:41:09","guid":{"rendered":"https:\/\/depts.washington.edu\/pandemicalliance\/?p=8527"},"modified":"2021-04-05T10:41:57","modified_gmt":"2021-04-05T17:41:57","slug":"clinical-characteristics-of-children-with-covid-19-a-meta-analysis","status":"publish","type":"post","link":"https:\/\/depts.washington.edu\/pandemicalliance\/2020\/07\/28\/clinical-characteristics-of-children-with-covid-19-a-meta-analysis\/","title":{"rendered":"Clinical Characteristics of Children With COVID-19: A Meta-Analysis"},"content":{"rendered":"<ul>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"46\" data-aria-posinset=\"2\" data-aria-level=\"1\"><span data-contrast=\"auto\">A meta-analysis (14<\/span><span data-contrast=\"auto\">\u00a0studies and 371 patients<\/span><span data-contrast=\"auto\">) of COVID-19 in children found that 17% (95% CI 9-27) are asy<\/span><span data-contrast=\"auto\">m<\/span><span data-contrast=\"auto\">ptomatic\u00a0<\/span><span data-contrast=\"auto\">(<\/span><span data-contrast=\"auto\">fever is the most common symptom<\/span><span data-contrast=\"auto\">)<\/span><span data-contrast=\"auto\">,\u00a0<\/span><span data-contrast=\"auto\">6<\/span><span data-contrast=\"auto\">7<\/span><span data-contrast=\"auto\">% (95%<\/span><span data-contrast=\"auto\">CI<\/span><span data-contrast=\"auto\">\u00a051-8<\/span><span data-contrast=\"auto\">1<\/span><span data-contrast=\"auto\">) were diagnosed with pneumonia,\u00a0<\/span><span data-contrast=\"auto\">and\u00a0<\/span><span data-contrast=\"auto\">incidence\u00a0<\/span><span data-contrast=\"auto\">of severe or critical illness is close to 0% (95% CI 0-1)<\/span><span data-contrast=\"auto\">.\u00a0<\/span><span data-contrast=\"auto\">Of those diagnosed with pneumonia, 5<\/span><span data-contrast=\"auto\">4<\/span><span data-contrast=\"auto\">% (95%CI 38-6<\/span><span data-contrast=\"auto\">9<\/span><span data-contrast=\"auto\">)<\/span><span data-contrast=\"auto\">\u00a0<\/span><span data-contrast=\"auto\">had ground-glass opacities detected on CT scan<\/span><span data-contrast=\"auto\">. An additional\u00a0<\/span><span data-contrast=\"auto\">19% were asymptomatic but had radiological features of pneumonia.\u00a0<\/span><span data-contrast=\"auto\">Most of the\u00a0included studies\u00a0were case reports or case series from China.\u00a0<\/span><span data-contrast=\"auto\">The authors also note this meta-analysis found a higher proportion of asymptomatic children than most studies from the US and Europe<\/span><span data-contrast=\"auto\">, which may reflect differences in testing policies.\u00a0<\/span><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li>\n<\/ul>\n<p><i><span data-contrast=\"none\">Ding et al. (2020). Clinical Characteristics of Children With COVID-19: A Meta-Analysis. Frontiers in Pediatrics.\u00a0<\/span><\/i><a href=\"https:\/\/doi.org\/10.3389\/fped.2020.00431\"><span data-contrast=\"none\">https:\/\/doi.org\/10.3389\/fped.2020.00431<\/span><\/a><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559685&quot;:720,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"<p>A meta-analysis (14\u00a0studies and 371 patients) of COVID-19 in children found that 17% (95% CI 9-27) are asymptomatic\u00a0(fever is the most common symptom),\u00a067% (95%CI\u00a051-81) were diagnosed with pneumonia,\u00a0and\u00a0incidence\u00a0of severe or critical illness is close to 0% (95% CI 0-1).\u00a0Of those diagnosed with pneumonia, 54% (95%CI 38-69)\u00a0had ground-glass opacities detected on CT scan. An additional\u00a019% were&#8230;<\/p>\n<div><a class=\"more\" href=\"https:\/\/depts.washington.edu\/pandemicalliance\/2020\/07\/28\/clinical-characteristics-of-children-with-covid-19-a-meta-analysis\/\">Read more<\/a><\/div>\n","protected":false},"author":8,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":"","_links_to":"","_links_to_target":""},"categories":[6],"tags":[],"topic":[20],"class_list":["post-8527","post","type-post","status-publish","format-standard","hentry","category-article-summary","topic-clinical-characteristics-and-health-care-setting"],"_links":{"self":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/8527","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/users\/8"}],"replies":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/comments?post=8527"}],"version-history":[{"count":1,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/8527\/revisions"}],"predecessor-version":[{"id":8528,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/8527\/revisions\/8528"}],"wp:attachment":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/media?parent=8527"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/categories?post=8527"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/tags?post=8527"},{"taxonomy":"topic","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/topic?post=8527"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}