{"id":8632,"date":"2021-04-05T10:03:53","date_gmt":"2021-04-05T17:03:53","guid":{"rendered":"https:\/\/depts.washington.edu\/pandemicalliance\/?p=8632"},"modified":"2021-04-06T10:05:01","modified_gmt":"2021-04-06T17:05:01","slug":"sars-cov-2-infection-is-asymptomatic-in-nearly-half-of-adults-with-robust-anti-spike-protein-receptor-binding-domain-antibody-response","status":"publish","type":"post","link":"https:\/\/depts.washington.edu\/pandemicalliance\/2021\/04\/05\/sars-cov-2-infection-is-asymptomatic-in-nearly-half-of-adults-with-robust-anti-spike-protein-receptor-binding-domain-antibody-response\/","title":{"rendered":"SARS-CoV-2 Infection Is Asymptomatic in Nearly Half of Adults with Robust Anti-Spike Protein Receptor-Binding Domain Antibody Response"},"content":{"rendered":"<ul>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">In a study of 4996 participants (aged 18\u201382 years, 34.5% men) from Greece with plasma antibodies against SARS-CoV-2 nucleocapsid protein between June and November 2020, 49% of seropositive cases (39\/79) reported no history of SARS-CoV-2 infection-related clinical symptoms. The majority of SARS-CoV-2 asymptomatic infections were \u201cunsuspected\u201d cases (26\/39) who had no known contact with a confirmed or suspected COVID-19 case. Anti-SARS-CoV-2 antibody levels against the spike-protein receptor binding domain were similar between symptomatic and asymptomatic individuals, with no differences by age or gender.<\/span><\/li>\n<\/ul>\n<p><i><span style=\"font-weight: 400\">Tsitsilonis et al. (Mar 2, 2021). SARS-CoV-2 Infection Is Asymptomatic in Nearly Half of Adults with Robust Anti-Spike Protein Receptor-Binding Domain Antibody Response. Vaccines. <\/span><\/i><a href=\"https:\/\/doi.org\/10.3390\/vaccines9030207\"><span style=\"font-weight: 400\">https:\/\/doi.org\/10.3390\/vaccines9030207<\/span><\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>In a study of 4996 participants (aged 18\u201382 years, 34.5% men) from Greece with plasma antibodies against SARS-CoV-2 nucleocapsid protein between June and November 2020, 49% of seropositive cases (39\/79) reported no history of SARS-CoV-2 infection-related clinical symptoms. The majority of SARS-CoV-2 asymptomatic infections were \u201cunsuspected\u201d cases (26\/39) who had no known contact with a&#8230;<\/p>\n<div><a class=\"more\" href=\"https:\/\/depts.washington.edu\/pandemicalliance\/2021\/04\/05\/sars-cov-2-infection-is-asymptomatic-in-nearly-half-of-adults-with-robust-anti-spike-protein-receptor-binding-domain-antibody-response\/\">Read more<\/a><\/div>\n","protected":false},"author":8,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":"","_links_to":"","_links_to_target":""},"categories":[6],"tags":[107,32],"topic":[21],"class_list":["post-8632","post","type-post","status-publish","format-standard","hentry","category-article-summary","tag-asymptomatic-infection","tag-immunity","topic-transmission"],"_links":{"self":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/8632","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/users\/8"}],"replies":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/comments?post=8632"}],"version-history":[{"count":1,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/8632\/revisions"}],"predecessor-version":[{"id":8633,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/8632\/revisions\/8633"}],"wp:attachment":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/media?parent=8632"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/categories?post=8632"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/tags?post=8632"},{"taxonomy":"topic","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/topic?post=8632"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}