{"id":8725,"date":"2020-08-04T11:08:56","date_gmt":"2020-08-04T18:08:56","guid":{"rendered":"https:\/\/depts.washington.edu\/pandemicalliance\/?p=8725"},"modified":"2021-04-06T11:09:37","modified_gmt":"2021-04-06T18:09:37","slug":"the-risk-and-prognosis-of-covid-19-infection-in-cancer-patients-a-systematic-review-and-meta-analysis","status":"publish","type":"post","link":"https:\/\/depts.washington.edu\/pandemicalliance\/2020\/08\/04\/the-risk-and-prognosis-of-covid-19-infection-in-cancer-patients-a-systematic-review-and-meta-analysis\/","title":{"rendered":"The Risk and Prognosis of COVID-19 Infection in Cancer Patients: A Systematic Review and Meta-Analysis"},"content":{"rendered":"<ul>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"48\" data-aria-posinset=\"2\" data-aria-level=\"1\"><span data-contrast=\"auto\">A systematic review and meta<\/span><span data-contrast=\"auto\">-a<\/span><span data-contrast=\"auto\">nalysis (n=22 studies\u00a0<\/span><span data-contrast=\"auto\">with<\/span><span data-contrast=\"auto\">\u00a01,018 cancer patients) found the prevalence of cancer among patients was 2.1% (95% C<\/span><span data-contrast=\"auto\">I<\/span><span data-contrast=\"auto\">\u00a01.3, 3%). Case fatality among these patients was 21.1% (95% CI 14.7, 27.6%)<\/span><span data-contrast=\"auto\">. The<\/span><span data-contrast=\"auto\">\u00a0probability\u00a0<\/span><span data-contrast=\"auto\">for severe\/critical disease\u00a0<\/span><span data-contrast=\"auto\">was 45.4% (95% CI 37.4, 53.3%),\u00a0<\/span><span data-contrast=\"auto\">for ICU admission was\u00a0<\/span><span data-contrast=\"auto\">14.5% (95% CI 8.5, 20.4%), and\u00a0<\/span><span data-contrast=\"auto\">need for mechanical ventilation was\u00a0<\/span><span data-contrast=\"auto\">11.7% (95% CI 5.5, 18.8%).\u00a0<\/span><span data-contrast=\"auto\">C<\/span><span data-contrast=\"auto\">OVID-19 patients with cancer<\/span><span data-contrast=\"auto\">\u00a0were found to have a higher odds of\u00a0<\/span><span data-contrast=\"auto\">mortality (OR<\/span><span data-contrast=\"auto\">=<\/span><span data-contrast=\"auto\">3.23, 95% CI 1.7, 6.1), severe\/critical disease (<\/span><span data-contrast=\"auto\">O<\/span><span data-contrast=\"auto\">R<\/span><span data-contrast=\"auto\">=<\/span><span data-contrast=\"auto\">3.9, 95% CI 2.7, 5.7), ICU admission (OR<\/span><span data-contrast=\"auto\">=<\/span><span data-contrast=\"auto\">3.1, 95% CI 1.9, 5.7) and mechanical ventilation (OR<\/span><span data-contrast=\"auto\">=<\/span><span data-contrast=\"auto\">4.9, 95% CI 1.3, 18.7)<\/span><span data-contrast=\"auto\">\u00a0compared with COVID-19 patients without cancer.<\/span><span data-contrast=\"auto\">\u00a0<\/span><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:240}\">\u00a0<\/span><\/li>\n<\/ul>\n<p><i><span data-contrast=\"none\">Elgohary<\/span><\/i><i><span data-contrast=\"none\">. (July 2020). The Risk and Prognosis of COVID-19 Infection in Cancer Patients: A Systematic Review and Meta-Analysis. Hematology\/Oncology and Stem Cell Therapy.\u00a0<\/span><\/i><a href=\"https:\/\/doi.org\/10.1016\/j.hemonc.2020.07.005\"><span data-contrast=\"none\">https:\/\/doi.org\/10.1016\/j.hemonc.2020.07.005<\/span><\/a><i><span data-contrast=\"none\">\u00a0<\/span><\/i><span data-ccp-props=\"{&quot;201341983&quot;:0,&quot;335559685&quot;:720,&quot;335559739&quot;:160,&quot;335559740&quot;:240}\">\u00a0<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"<p>A systematic review and meta-analysis (n=22 studies\u00a0with\u00a01,018 cancer patients) found the prevalence of cancer among patients was 2.1% (95% CI\u00a01.3, 3%). Case fatality among these patients was 21.1% (95% CI 14.7, 27.6%). The\u00a0probability\u00a0for severe\/critical disease\u00a0was 45.4% (95% CI 37.4, 53.3%),\u00a0for ICU admission was\u00a014.5% (95% CI 8.5, 20.4%), and\u00a0need for mechanical ventilation was\u00a011.7% (95% CI 5.5,&#8230;<\/p>\n<div><a class=\"more\" href=\"https:\/\/depts.washington.edu\/pandemicalliance\/2020\/08\/04\/the-risk-and-prognosis-of-covid-19-infection-in-cancer-patients-a-systematic-review-and-meta-analysis\/\">Read more<\/a><\/div>\n","protected":false},"author":8,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":"","_links_to":"","_links_to_target":""},"categories":[6],"tags":[],"topic":[20],"class_list":["post-8725","post","type-post","status-publish","format-standard","hentry","category-article-summary","topic-clinical-characteristics-and-health-care-setting"],"_links":{"self":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/8725","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/users\/8"}],"replies":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/comments?post=8725"}],"version-history":[{"count":1,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/8725\/revisions"}],"predecessor-version":[{"id":8726,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/8725\/revisions\/8726"}],"wp:attachment":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/media?parent=8725"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/categories?post=8725"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/tags?post=8725"},{"taxonomy":"topic","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/topic?post=8725"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}