{"id":873,"date":"2020-09-11T21:26:06","date_gmt":"2020-09-12T04:26:06","guid":{"rendered":"https:\/\/depts.washington.edu\/pandemicalliance\/?p=873"},"modified":"2020-09-11T21:26:06","modified_gmt":"2020-09-12T04:26:06","slug":"racial-ethnic-variation-in-nasal-gene-expression-of-transmembrane-serine-protease-2-tmprss2","status":"publish","type":"post","link":"https:\/\/depts.washington.edu\/pandemicalliance\/2020\/09\/11\/racial-ethnic-variation-in-nasal-gene-expression-of-transmembrane-serine-protease-2-tmprss2\/","title":{"rendered":"Racial\/Ethnic Variation in Nasal Gene Expression of Transmembrane Serine Protease 2 (TMPRSS2)"},"content":{"rendered":"<ul>\n<li>A study of nasal epithelial gene expression in a racially\/ethnically diverse cohort (n=305) showed significantly higher expression of transmembrane serine protease 2 (TMPRSS2) in Black individuals compared with Asian, Latino, mixed race\/ethnicity, and white individuals. Given the essential role of TMPRSS2 in SARS-CoV-2 entry, higher nasal expression of TMPRSS2 may be one of the many factors that contribute to a higher burden of COVID-19 among Black individuals.\n<p><em>Bunyavanich et al. (Sept 10, 2020). Racial\/Ethnic Variation in Nasal Gene Expression of Transmembrane Serine Protease 2 (TMPRSS2). JAMA. <a href=\"http:\/\/discover.uw.edu\/UAj001O0xQ3AyO00q80001Z\">https:\/\/doi.org\/10.1001\/jama.2020.17386<\/a><\/em><\/li>\n<\/ul>\n","protected":false},"excerpt":{"rendered":"<p>A study of nasal epithelial gene expression in a racially\/ethnically diverse cohort (n=305) showed significantly higher expression of transmembrane serine protease 2 (TMPRSS2) in Black individuals compared with Asian, Latino, mixed race\/ethnicity, and white individuals. Given the essential role of TMPRSS2 in SARS-CoV-2 entry, higher nasal expression of TMPRSS2 may be one of the many&#8230;<\/p>\n<div><a class=\"more\" href=\"https:\/\/depts.washington.edu\/pandemicalliance\/2020\/09\/11\/racial-ethnic-variation-in-nasal-gene-expression-of-transmembrane-serine-protease-2-tmprss2\/\">Read more<\/a><\/div>\n","protected":false},"author":5,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":"","_links_to":"","_links_to_target":""},"categories":[6],"tags":[42],"topic":[16],"class_list":["post-873","post","type-post","status-publish","format-standard","hentry","category-article-summary","tag-disparities","topic-public-health-policy-and-practice"],"_links":{"self":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/873","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/users\/5"}],"replies":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/comments?post=873"}],"version-history":[{"count":1,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/873\/revisions"}],"predecessor-version":[{"id":874,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/873\/revisions\/874"}],"wp:attachment":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/media?parent=873"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/categories?post=873"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/tags?post=873"},{"taxonomy":"topic","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/topic?post=873"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}