{"id":8763,"date":"2020-08-06T11:30:00","date_gmt":"2020-08-06T18:30:00","guid":{"rendered":"https:\/\/depts.washington.edu\/pandemicalliance\/?p=8763"},"modified":"2021-04-06T11:30:43","modified_gmt":"2021-04-06T18:30:43","slug":"clinical-course-and-molecular-viral-shedding-among-asymptomatic-and-symptomatic-patients-with-sars-cov-2-infection-in-a-community-treatment-center-in-the-republic-of-korea","status":"publish","type":"post","link":"https:\/\/depts.washington.edu\/pandemicalliance\/2020\/08\/06\/clinical-course-and-molecular-viral-shedding-among-asymptomatic-and-symptomatic-patients-with-sars-cov-2-infection-in-a-community-treatment-center-in-the-republic-of-korea\/","title":{"rendered":"Clinical Course and Molecular Viral Shedding Among Asymptomatic and Symptomatic Patients With SARS-CoV-2 Infection in a Community Treatment Center in the Republic of Korea"},"content":{"rendered":"<ul>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"34\" data-aria-posinset=\"1\" data-aria-level=\"1\"><span data-contrast=\"auto\">Lee et al.\u00a0<\/span><span data-contrast=\"auto\">examined<\/span><span data-contrast=\"auto\">\u00a0<\/span><span data-contrast=\"auto\">viral shedding among\u00a0<\/span><span data-contrast=\"auto\">asymptomatic (36<\/span><span data-contrast=\"auto\">%) and\u00a0<\/span><span data-contrast=\"auto\">symptomatic (64%)\u00a0<\/span><span data-contrast=\"auto\">patients with\u00a0<\/span><span data-contrast=\"auto\">SARS-CoV-2\u00a0<\/span><span data-contrast=\"auto\">infection who were\u00a0<\/span><span data-contrast=\"auto\">isolated in a community treatment center<\/span><span data-contrast=\"auto\">\u00a0in\u00a0<\/span><span data-contrast=\"auto\">South\u00a0<\/span><span data-contrast=\"auto\">Korea<\/span><span data-contrast=\"auto\">\u00a0(n=303)<\/span><span data-contrast=\"auto\">\u00a0and found that\u00a0<\/span><span data-contrast=\"auto\">viral loads did not differ significantly between<\/span><span data-contrast=\"auto\">\u00a0the groups\u00a0<\/span><span data-contrast=\"auto\">based on\u00a0<\/span><span data-contrast=\"auto\">amplification<\/span><span data-contrast=\"auto\">\u00a0<\/span><span data-contrast=\"auto\">of 3\u00a0<\/span><span data-contrast=\"auto\">viral\u00a0<\/span><span data-contrast=\"auto\">gene<\/span><span data-contrast=\"auto\">s<\/span><span data-contrast=\"auto\">\u00a0(<\/span><i><span data-contrast=\"auto\">R<\/span><\/i><i><span data-contrast=\"auto\">dR<\/span><\/i><i><span data-contrast=\"auto\">p<\/span><\/i><i><span data-contrast=\"auto\">, N, env<\/span><\/i><span data-contrast=\"auto\">)<\/span><span data-contrast=\"auto\">. D<\/span><span data-contrast=\"auto\">uring isolation, the proportion<\/span><span data-contrast=\"auto\">\u00a0<\/span><span data-contrast=\"auto\">who converted to\u00a0<\/span><span data-contrast=\"auto\">a\u00a0<\/span><span data-contrast=\"auto\">ne<\/span><span data-contrast=\"auto\">g<\/span><span data-contrast=\"auto\">ative<\/span><span data-contrast=\"auto\">\u00a0<\/span><span data-contrast=\"auto\">RT-PCR\u00a0<\/span><span data-contrast=\"auto\">test result<\/span><span data-contrast=\"auto\">\u00a0<\/span><span data-contrast=\"auto\">w<\/span><span data-contrast=\"auto\">as<\/span><span data-contrast=\"auto\">\u00a0similar between asymptomatic and symptomatic patients (34% vs. 30% at day 14, 75% vs. 70% at day 21)<\/span><span data-contrast=\"auto\">\u00a0without a statisti<\/span><span data-contrast=\"auto\">cally\u00a0<\/span><span data-contrast=\"auto\">significant difference\u00a0<\/span><span data-contrast=\"auto\">in\u00a0<\/span><span data-contrast=\"auto\">time<\/span><span data-contrast=\"auto\">&#8211;<\/span><span data-contrast=\"auto\">to<\/span><span data-contrast=\"auto\">&#8211;<\/span><span data-contrast=\"auto\">conversion (<\/span><span data-contrast=\"auto\">median 17 days among\u00a0<\/span><span data-contrast=\"auto\">asymptomatic<\/span><span data-contrast=\"auto\">\u00a0v. 19.5\u00a0<\/span><span data-contrast=\"auto\">days\u00a0<\/span><span data-contrast=\"auto\">among\u00a0<\/span><span data-contrast=\"auto\">symptomatic<\/span><span data-contrast=\"auto\">\u00a0patients<\/span><span data-contrast=\"auto\">, p<\/span><span data-contrast=\"auto\">-value<\/span><span data-contrast=\"auto\">\u00a0=\u00a0<\/span><span data-contrast=\"auto\">0<\/span><span data-contrast=\"auto\">.07).<\/span><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li>\n<\/ul>\n<p><i><span data-contrast=\"none\">Lee et al. (Aug 6, 2020). Clinical Course and Molecular Viral Shedding Among Asymptomatic and Symptomatic Patients With SARS-CoV-2 Infection in a Community Treatment Center in the Republic of Korea. JAMA Internal Medicine.\u00a0<\/span><\/i><a href=\"https:\/\/doi.org\/doi:10.1001\/jamainternmed.2020.3862\"><span data-contrast=\"none\">https:\/\/doi.org\/doi:10.1001\/jamainternmed.2020.3862<\/span><\/a><i><span data-contrast=\"none\">\u00a0<\/span><\/i><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559685&quot;:720,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Lee et al.\u00a0examined\u00a0viral shedding among\u00a0asymptomatic (36%) and\u00a0symptomatic (64%)\u00a0patients with\u00a0SARS-CoV-2\u00a0infection who were\u00a0isolated in a community treatment center\u00a0in\u00a0South\u00a0Korea\u00a0(n=303)\u00a0and found that\u00a0viral loads did not differ significantly between\u00a0the groups\u00a0based on\u00a0amplification\u00a0of 3\u00a0viral\u00a0genes\u00a0(RdRp, N, env). During isolation, the proportion\u00a0who converted to\u00a0a\u00a0negative\u00a0RT-PCR\u00a0test result\u00a0was\u00a0similar between asymptomatic and symptomatic patients (34% vs. 30% at day 14, 75% vs. 70% at day 21)\u00a0without a statistically\u00a0significant&#8230;<\/p>\n<div><a class=\"more\" href=\"https:\/\/depts.washington.edu\/pandemicalliance\/2020\/08\/06\/clinical-course-and-molecular-viral-shedding-among-asymptomatic-and-symptomatic-patients-with-sars-cov-2-infection-in-a-community-treatment-center-in-the-republic-of-korea\/\">Read more<\/a><\/div>\n","protected":false},"author":8,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":"","_links_to":"","_links_to_target":""},"categories":[6],"tags":[],"topic":[21],"class_list":["post-8763","post","type-post","status-publish","format-standard","hentry","category-article-summary","topic-transmission"],"_links":{"self":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/8763","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/users\/8"}],"replies":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/comments?post=8763"}],"version-history":[{"count":1,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/8763\/revisions"}],"predecessor-version":[{"id":8764,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/8763\/revisions\/8764"}],"wp:attachment":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/media?parent=8763"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/categories?post=8763"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/tags?post=8763"},{"taxonomy":"topic","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/topic?post=8763"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}