{"id":8796,"date":"2021-04-06T10:14:43","date_gmt":"2021-04-06T17:14:43","guid":{"rendered":"https:\/\/depts.washington.edu\/pandemicalliance\/?p=8796"},"modified":"2021-04-07T10:15:35","modified_gmt":"2021-04-07T17:15:35","slug":"covid-19-mrna-vaccines-drive-differential-fc-functional-profiles-in-pregnant-lactating-and-non-pregnant-women","status":"publish","type":"post","link":"https:\/\/depts.washington.edu\/pandemicalliance\/2021\/04\/06\/covid-19-mrna-vaccines-drive-differential-fc-functional-profiles-in-pregnant-lactating-and-non-pregnant-women\/","title":{"rendered":"COVID-19 MRNA Vaccines Drive Differential Fc-Functional Profiles in Pregnant Lactating and Non-Pregnant Women"},"content":{"rendered":"<ul>\n<li style=\"font-weight: 400\"><i><span style=\"font-weight: 400\">\u00a0[Pre-print, not peer-reviewed]<\/span><\/i><span style=\"font-weight: 400\"> The antibody response induced by mRNA vaccines (Moderna and Pfizer-BioNTech) after the first dose was lower among pregnant (n=84) and lactating (n=31) women compared to non-pregnant age-matched controls (n=16), but after the second dose no significant differences were observed. Differences in antibody response after the first dose related to lower antibody titers and delayed kinetics in Fc-receptor-binding and antibody effector functions.<\/span><\/li>\n<\/ul>\n<p><i><span style=\"font-weight: 400\">Atyeo et al.\u00a0(Apr 5, 2021). COVID-19 MRNA Vaccines Drive Differential Fc-Functional Profiles in Pregnant Lactating and Non-Pregnant Women. Pre-print downloaded Apr 6 from <\/span><\/i><a href=\"https:\/\/doi.org\/10.1101\/2021.04.04.438404\"><span style=\"font-weight: 400\">https:\/\/doi.org\/10.1101\/2021.04.04.438404<\/span><\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u00a0[Pre-print, not peer-reviewed] The antibody response induced by mRNA vaccines (Moderna and Pfizer-BioNTech) after the first dose was lower among pregnant (n=84) and lactating (n=31) women compared to non-pregnant age-matched controls (n=16), but after the second dose no significant differences were observed. Differences in antibody response after the first dose related to lower antibody titers&#8230;<\/p>\n<div><a class=\"more\" href=\"https:\/\/depts.washington.edu\/pandemicalliance\/2021\/04\/06\/covid-19-mrna-vaccines-drive-differential-fc-functional-profiles-in-pregnant-lactating-and-non-pregnant-women\/\">Read more<\/a><\/div>\n","protected":false},"author":8,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":"","_links_to":"","_links_to_target":""},"categories":[6],"tags":[50,33],"topic":[31],"class_list":["post-8796","post","type-post","status-publish","format-standard","hentry","category-article-summary","tag-pregnancy","tag-vaccines","topic-vaccines-and-immunity"],"_links":{"self":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/8796","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/users\/8"}],"replies":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/comments?post=8796"}],"version-history":[{"count":1,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/8796\/revisions"}],"predecessor-version":[{"id":8797,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/8796\/revisions\/8797"}],"wp:attachment":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/media?parent=8796"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/categories?post=8796"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/tags?post=8796"},{"taxonomy":"topic","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/topic?post=8796"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}