{"id":8834,"date":"2021-04-07T11:01:33","date_gmt":"2021-04-07T18:01:33","guid":{"rendered":"https:\/\/depts.washington.edu\/pandemicalliance\/?p=8834"},"modified":"2021-04-12T11:02:23","modified_gmt":"2021-04-12T18:02:23","slug":"anti-sars-cov-2-rbd-igg-responses-in-convalescent-versus-naive-bnt162b2-vaccine-recipients","status":"publish","type":"post","link":"https:\/\/depts.washington.edu\/pandemicalliance\/2021\/04\/07\/anti-sars-cov-2-rbd-igg-responses-in-convalescent-versus-naive-bnt162b2-vaccine-recipients\/","title":{"rendered":"Anti-SARS-CoV-2 RBD IgG Responses in Convalescent versus Na\u00efve BNT162b2 Vaccine Recipients"},"content":{"rendered":"<ul>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">IgG responses measured 14 days after the first and second dose of the Pfizer-BioNTech vaccine among convalescent individuals (n = 12) and age- and sex-matched individuals with no prior infection (n = 54) showed that convalescent individuals showed higher absolute anti-S1\/S2 IgG levels (220\u00a0\u00b1\u00a042 vs. 37\u00a0\u00b1\u00a03\u00a0AU\/ml) compared to\u00a0na\u00efve\u00a0vaccinees at 14 days after the first dose. IgG levels of convalescent individuals 14\u00a0days after the first dose were similar to those of\u00a0individuals without prior infection after the second dose. 2% of\u00a0na\u00efve\u00a0vaccine recipients and 75% of convalescent individuals showed IgG levels higher than 80 AU\/ml after the first dose of vaccine, which the authors note has been shown to predict neutralizing antibody titers.<\/span><\/li>\n<\/ul>\n<p><i><span style=\"font-weight: 400\">Azzi et al.\u00a0(Mar 2021). Anti-SARS-CoV-2 RBD IgG Responses in Convalescent versus Na\u00efve BNT162b2 Vaccine Recipients. Vaccine. <\/span><\/i><a href=\"https:\/\/doi.org\/10.1016\/j.vaccine.2021.03.086\"><span style=\"font-weight: 400\">https:\/\/doi.org\/10.1016\/j.vaccine.2021.03.086<\/span><\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>IgG responses measured 14 days after the first and second dose of the Pfizer-BioNTech vaccine among convalescent individuals (n = 12) and age- and sex-matched individuals with no prior infection (n = 54) showed that convalescent individuals showed higher absolute anti-S1\/S2 IgG levels (220\u00a0\u00b1\u00a042 vs. 37\u00a0\u00b1\u00a03\u00a0AU\/ml) compared to\u00a0na\u00efve\u00a0vaccinees at 14 days after the first dose&#8230;.<\/p>\n<div><a class=\"more\" href=\"https:\/\/depts.washington.edu\/pandemicalliance\/2021\/04\/07\/anti-sars-cov-2-rbd-igg-responses-in-convalescent-versus-naive-bnt162b2-vaccine-recipients\/\">Read more<\/a><\/div>\n","protected":false},"author":8,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":"","_links_to":"","_links_to_target":""},"categories":[6],"tags":[142],"topic":[31],"class_list":["post-8834","post","type-post","status-publish","format-standard","hentry","category-article-summary","tag-vaccine","topic-vaccines-and-immunity"],"_links":{"self":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/8834","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/users\/8"}],"replies":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/comments?post=8834"}],"version-history":[{"count":1,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/8834\/revisions"}],"predecessor-version":[{"id":8835,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/8834\/revisions\/8835"}],"wp:attachment":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/media?parent=8834"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/categories?post=8834"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/tags?post=8834"},{"taxonomy":"topic","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/topic?post=8834"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}