{"id":8853,"date":"2021-04-08T11:17:44","date_gmt":"2021-04-08T18:17:44","guid":{"rendered":"https:\/\/depts.washington.edu\/pandemicalliance\/?p=8853"},"modified":"2021-04-13T10:54:09","modified_gmt":"2021-04-13T17:54:09","slug":"s-gene-target-failure-as-a-marker-of-variant-b-1-1-7-among-sars-cov-2-isolates-in-the-greater-toronto-area-december-2020-to-march-2021","status":"publish","type":"post","link":"https:\/\/depts.washington.edu\/pandemicalliance\/2021\/04\/08\/s-gene-target-failure-as-a-marker-of-variant-b-1-1-7-among-sars-cov-2-isolates-in-the-greater-toronto-area-december-2020-to-march-2021\/","title":{"rendered":"S-Gene Target Failure as a Marker of Variant B.1.1.7 Among SARS-CoV-2 Isolates in the Greater Toronto Area, December 2020 to March 2021"},"content":{"rendered":"<ul>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">The B.1.1.7 SARS-CoV-2 variant (first described in the UK) rapidly became the dominant circulating strain in the greater Toronto, Canada area between December 2020 and March 2021. Based on PCR S-gene target failure, which is strongly associated with the B.1.1.7 variant, 2% of samples were inferred to be the B.1.1.7 variant in mid-December 2020, which increased to 75% by March 31, 2021.<\/span><\/li>\n<\/ul>\n<p><i><span style=\"font-weight: 400\">Brown et al. (Apr 8, 2021). S-Gene Target Failure as a Marker of Variant B.1.1.7 Among SARS-CoV-2 Isolates in the Greater Toronto Area, December 2020 to March 2021. JAMA. <\/span><\/i><a href=\"https:\/\/doi.org\/10.1001\/jama.2021.5607\"><span style=\"font-weight: 400\">https:\/\/doi.org\/10.1001\/jama.2021.5607<\/span><\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>The B.1.1.7 SARS-CoV-2 variant (first described in the UK) rapidly became the dominant circulating strain in the greater Toronto, Canada area between December 2020 and March 2021. Based on PCR S-gene target failure, which is strongly associated with the B.1.1.7 variant, 2% of samples were inferred to be the B.1.1.7 variant in mid-December 2020, which&#8230;<\/p>\n<div><a class=\"more\" href=\"https:\/\/depts.washington.edu\/pandemicalliance\/2021\/04\/08\/s-gene-target-failure-as-a-marker-of-variant-b-1-1-7-among-sars-cov-2-isolates-in-the-greater-toronto-area-december-2020-to-march-2021\/\">Read more<\/a><\/div>\n","protected":false},"author":8,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":"","_links_to":"","_links_to_target":""},"categories":[6],"tags":[40,159],"topic":[24],"class_list":["post-8853","post","type-post","status-publish","format-standard","hentry","category-article-summary","tag-geographic-spread","tag-variants","topic-geographic-spread"],"_links":{"self":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/8853","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/users\/8"}],"replies":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/comments?post=8853"}],"version-history":[{"count":1,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/8853\/revisions"}],"predecessor-version":[{"id":8854,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/8853\/revisions\/8854"}],"wp:attachment":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/media?parent=8853"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/categories?post=8853"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/tags?post=8853"},{"taxonomy":"topic","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/topic?post=8853"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}