{"id":8859,"date":"2021-04-08T11:20:16","date_gmt":"2021-04-08T18:20:16","guid":{"rendered":"https:\/\/depts.washington.edu\/pandemicalliance\/?p=8859"},"modified":"2021-04-13T10:52:58","modified_gmt":"2021-04-13T17:52:58","slug":"cerc-002-a-human-anti-light-mab-reduces-respiratory-failure-and-death-in-hospitalized-covid-19-ards-patients","status":"publish","type":"post","link":"https:\/\/depts.washington.edu\/pandemicalliance\/2021\/04\/08\/cerc-002-a-human-anti-light-mab-reduces-respiratory-failure-and-death-in-hospitalized-covid-19-ards-patients\/","title":{"rendered":"CERC-002 a Human Anti-LIGHT mAb Reduces Respiratory Failure and Death in Hospitalized COVID-19 ARDS Patients"},"content":{"rendered":"<ul>\n<li style=\"font-weight: 400\"><i><span style=\"font-weight: 400\">[Pre-print, not peer-reviewed]<\/span><\/i><span style=\"font-weight: 400\"> The monoclonal antibody (mAb) treatment CERC-002 reduced mortality and the risk of respiratory failure through day 28 compared to placebo (84% vs 65%; p=0.044) among hospitalized COVID-19 patients with mild-to-moderate acute respiratory distress syndrome (ARDS) according to a randomized placebo-controlled study (n=83). Efficacy was highest among patients \u226560 years old (77% vs 47%; p=0.042).<\/span><\/li>\n<\/ul>\n<p><i><span style=\"font-weight: 400\">Perlin et al.\u00a0(Apr 7, 2021). CERC-002 a Human Anti-LIGHT mAb Reduces Respiratory Failure and Death in Hospitalized COVID-19 ARDS Patients. Pre-print downloaded Apr 8 from <\/span><\/i><a href=\"https:\/\/doi.org\/10.1101\/2021.04.03.21254748\"><span style=\"font-weight: 400\">https:\/\/doi.org\/10.1101\/2021.04.03.21254748<\/span><\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>[Pre-print, not peer-reviewed] The monoclonal antibody (mAb) treatment CERC-002 reduced mortality and the risk of respiratory failure through day 28 compared to placebo (84% vs 65%; p=0.044) among hospitalized COVID-19 patients with mild-to-moderate acute respiratory distress syndrome (ARDS) according to a randomized placebo-controlled study (n=83). Efficacy was highest among patients \u226560 years old (77% vs&#8230;<\/p>\n<div><a class=\"more\" href=\"https:\/\/depts.washington.edu\/pandemicalliance\/2021\/04\/08\/cerc-002-a-human-anti-light-mab-reduces-respiratory-failure-and-death-in-hospitalized-covid-19-ards-patients\/\">Read more<\/a><\/div>\n","protected":false},"author":8,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":"","_links_to":"","_links_to_target":""},"categories":[6],"tags":[28],"topic":[19],"class_list":["post-8859","post","type-post","status-publish","format-standard","hentry","category-article-summary","tag-treatment","topic-testing-and-treatment"],"_links":{"self":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/8859","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/users\/8"}],"replies":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/comments?post=8859"}],"version-history":[{"count":1,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/8859\/revisions"}],"predecessor-version":[{"id":8860,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/8859\/revisions\/8860"}],"wp:attachment":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/media?parent=8859"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/categories?post=8859"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/tags?post=8859"},{"taxonomy":"topic","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/topic?post=8859"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}