{"id":8892,"date":"2021-04-09T11:40:03","date_gmt":"2021-04-09T18:40:03","guid":{"rendered":"https:\/\/depts.washington.edu\/pandemicalliance\/?p=8892"},"modified":"2021-04-12T11:40:54","modified_gmt":"2021-04-12T18:40:54","slug":"single-dose-bnt162b2-vaccine-protects-against-asymptomatic-sars-cov-2-infection","status":"publish","type":"post","link":"https:\/\/depts.washington.edu\/pandemicalliance\/2021\/04\/09\/single-dose-bnt162b2-vaccine-protects-against-asymptomatic-sars-cov-2-infection\/","title":{"rendered":"Single-Dose BNT162b2 Vaccine Protects against Asymptomatic SARS-CoV-2 Infection"},"content":{"rendered":"<ul>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">A study of health care workers (N=~9,000) employed at Cambridge University Hospitals in Great Britain found that 1 dose of the Pfizer-BioNTech COVID-19 vaccine was associated with a 4-fold reduction in asymptomatic SARS-CoV-2 infection \u226512 days post-vaccination, from 0.8% to 0.2% <\/span><i><span style=\"font-weight: 400\">[EDITORIAL NOTE: This is equivalent to a 75% vaccine efficacy]<\/span><\/i><span style=\"font-weight: 400\">.\u00a0 Additionally, the median cycle threshold value of positive tests among those who became infected showed a non-significant increasing trend of higher viral loads among unvaccinated HCWs compared to HCWs \u226512 days post- vaccination, potentially indicating that vaccinated individuals who subsequently become infected may have lower viral loads. The authors suggest that mass first-dose vaccination may reduce SARS-CoV-2 transmission.\u00a0<\/span><\/li>\n<\/ul>\n<p><i><span style=\"font-weight: 400\">Jones et al. (Apr 8, 2021). Single-Dose BNT162b2 Vaccine Protects against Asymptomatic SARS-CoV-2 Infection. ELife. <\/span><\/i><a href=\"https:\/\/doi.org\/10.7554\/eLife.68808\"><span style=\"font-weight: 400\">https:\/\/doi.org\/10.7554\/eLife.68808<\/span><\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>A study of health care workers (N=~9,000) employed at Cambridge University Hospitals in Great Britain found that 1 dose of the Pfizer-BioNTech COVID-19 vaccine was associated with a 4-fold reduction in asymptomatic SARS-CoV-2 infection \u226512 days post-vaccination, from 0.8% to 0.2% [EDITORIAL NOTE: This is equivalent to a 75% vaccine efficacy].\u00a0 Additionally, the median cycle&#8230;<\/p>\n<div><a class=\"more\" href=\"https:\/\/depts.washington.edu\/pandemicalliance\/2021\/04\/09\/single-dose-bnt162b2-vaccine-protects-against-asymptomatic-sars-cov-2-infection\/\">Read more<\/a><\/div>\n","protected":false},"author":8,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":"","_members_access_role":[],"_members_access_error":"","_links_to":"","_links_to_target":""},"categories":[6],"tags":[142],"topic":[31],"class_list":["post-8892","post","type-post","status-publish","format-standard","hentry","category-article-summary","tag-vaccine","topic-vaccines-and-immunity"],"_links":{"self":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/8892","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/users\/8"}],"replies":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/comments?post=8892"}],"version-history":[{"count":1,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/8892\/revisions"}],"predecessor-version":[{"id":8893,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/8892\/revisions\/8893"}],"wp:attachment":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/media?parent=8892"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/categories?post=8892"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/tags?post=8892"},{"taxonomy":"topic","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/topic?post=8892"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}