{"id":8943,"date":"2021-04-12T10:32:52","date_gmt":"2021-04-12T17:32:52","guid":{"rendered":"https:\/\/depts.washington.edu\/pandemicalliance\/?p=8943"},"modified":"2021-04-13T10:33:33","modified_gmt":"2021-04-13T17:33:33","slug":"infectivity-of-severe-acute-respiratory-syndrome-coronavirus-2-in-children-compared-with-adults","status":"publish","type":"post","link":"https:\/\/depts.washington.edu\/pandemicalliance\/2021\/04\/12\/infectivity-of-severe-acute-respiratory-syndrome-coronavirus-2-in-children-compared-with-adults\/","title":{"rendered":"Infectivity of Severe Acute Respiratory Syndrome Coronavirus 2 in Children Compared with Adults"},"content":{"rendered":"<ul>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">Compared with adults, children with SARS-CoV-2 positive nasopharyngeal swabs (NPS) were less likely to grow virus in culture <\/span><span style=\"font-weight: 400\">(OR=0.45) <\/span><span style=\"font-weight: 400\">and ha<\/span><span style=\"font-weight: 400\">d<\/span><span style=\"font-weight: 400\"> lower viral concentrations<\/span><span style=\"font-weight: 400\"> (cycle threshold: 25.1 age\u2264 10 years, 22.2 age 11\u201317 years, and 18.7 in adults)<\/span><span style=\"font-weight: 400\">, suggesting that children may <\/span><span style=\"font-weight: 400\">be less likely to transmit infectious<\/span><span style=\"font-weight: 400\"> virus. The analysis included samples from children (n = 175) and adults (n = 130) infected with SARS-CoV-2 and their close contacts between March and December 2020.\u00a0 The median number of infectious particles (via 50% tissue culture infective dose per mL) was also significantly lower in children aged 11\u201317 years than adults.\u00a0<\/span><\/li>\n<\/ul>\n<p><i><span style=\"font-weight: 400\">Bullard et al.\u00a0(Apr 9, 2021). Infectivity of Severe Acute Respiratory Syndrome Coronavirus 2 in Children Compared with Adults. Canadian Medical Association Journal. <\/span><\/i><a href=\"https:\/\/doi.org\/10.1503\/cmaj.210263\"><span style=\"font-weight: 400\">https:\/\/doi.org\/10.1503\/cmaj.210263<\/span><\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Compared with adults, children with SARS-CoV-2 positive nasopharyngeal swabs (NPS) were less likely to grow virus in culture (OR=0.45) and had lower viral concentrations (cycle threshold: 25.1 age\u2264 10 years, 22.2 age 11\u201317 years, and 18.7 in adults), suggesting that children may be less likely to transmit infectious virus. The analysis included samples from children&#8230;<\/p>\n<div><a class=\"more\" href=\"https:\/\/depts.washington.edu\/pandemicalliance\/2021\/04\/12\/infectivity-of-severe-acute-respiratory-syndrome-coronavirus-2-in-children-compared-with-adults\/\">Read more<\/a><\/div>\n","protected":false},"author":8,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":"","_links_to":"","_links_to_target":""},"categories":[6],"tags":[41,38],"topic":[21],"class_list":["post-8943","post","type-post","status-publish","format-standard","hentry","category-article-summary","tag-children","tag-transmission","topic-transmission"],"_links":{"self":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/8943","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/users\/8"}],"replies":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/comments?post=8943"}],"version-history":[{"count":1,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/8943\/revisions"}],"predecessor-version":[{"id":8944,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/8943\/revisions\/8944"}],"wp:attachment":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/media?parent=8943"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/categories?post=8943"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/tags?post=8943"},{"taxonomy":"topic","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/topic?post=8943"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}