{"id":9010,"date":"2020-08-12T11:18:42","date_gmt":"2020-08-12T18:18:42","guid":{"rendered":"https:\/\/depts.washington.edu\/pandemicalliance\/?p=9010"},"modified":"2021-04-13T11:19:19","modified_gmt":"2021-04-13T18:19:19","slug":"strategic-anti-sars-cov-2-serology-testing-in-a-low-prevalence-pandemic-the-covid-19-contact-coco-study-in-health-care-professionals","status":"publish","type":"post","link":"https:\/\/depts.washington.edu\/pandemicalliance\/2020\/08\/12\/strategic-anti-sars-cov-2-serology-testing-in-a-low-prevalence-pandemic-the-covid-19-contact-coco-study-in-health-care-professionals\/","title":{"rendered":"Strategic Anti-SARS-CoV-2 Serology Testing in a Low Prevalence Pandemic The COVID-19 Contact (CoCo) Study in Health Care Professionals"},"content":{"rendered":"<ul>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"2\" data-aria-posinset=\"2\" data-aria-level=\"1\"><i><span data-contrast=\"none\">[pre-print, not peer-reviewed]<\/span><\/i><span data-contrast=\"auto\">\u00a0<\/span><span data-contrast=\"auto\">A longitudinal cohort study of frontline healthcare professionals in a large German university hospital (n=217 participants, corresponding to 1,080 weekly measurements over 6 weeks)<\/span><span data-contrast=\"auto\">\u00a0found a<\/span><span data-contrast=\"auto\">\u00a0cumulative incidence of 1.8%\u00a0<\/span><span data-contrast=\"auto\">for<\/span><span data-contrast=\"auto\">\u00a0seroconversion to\u00a0<\/span><span data-contrast=\"auto\">anti-SARS CoV-2<\/span><span data-contrast=\"auto\">\u00a0seropositivity by ELISA. Confirmatory testing indicated that only 1 of the 8 initial positive results were true positives, resulting in a true cumulative incidence of 0.5%. The authors\u00a0<\/span><span data-contrast=\"auto\">caution<\/span><span data-contrast=\"auto\">\u00a0that the results of a single positive serology test\u00a0<\/span><span data-contrast=\"auto\">should be interpreted with caution\u00a0<\/span><span data-contrast=\"auto\">in a\u00a0<\/span><span data-contrast=\"auto\">low prevalence\u00a0<\/span><span data-contrast=\"auto\">setting.<\/span><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li>\n<\/ul>\n<p><i><span data-contrast=\"none\">Behrens et al. (Aug 7, 2020). Strategic Anti-SARS-CoV-2 Serology Testing in a Low Prevalence Pandemic The COVID-19 Contact (CoCo) Study in Health Care Professionals.\u00a0<\/span><\/i><i><span data-contrast=\"none\">Pre-print\u00a0downloaded\u00a0Aug 12 from<\/span><\/i><span data-contrast=\"auto\">\u00a0<\/span><a href=\"https:\/\/doi.org\/10.1101\/2020.08.06.20169250\"><span data-contrast=\"none\">https:\/\/doi.org\/10.1101\/2020.08.06.20169250<\/span><\/a><span data-ccp-props=\"{&quot;201341983&quot;:0,&quot;335559685&quot;:720,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"<p>[pre-print, not peer-reviewed]\u00a0A longitudinal cohort study of frontline healthcare professionals in a large German university hospital (n=217 participants, corresponding to 1,080 weekly measurements over 6 weeks)\u00a0found a\u00a0cumulative incidence of 1.8%\u00a0for\u00a0seroconversion to\u00a0anti-SARS CoV-2\u00a0seropositivity by ELISA. Confirmatory testing indicated that only 1 of the 8 initial positive results were true positives, resulting in a true cumulative incidence&#8230;<\/p>\n<div><a class=\"more\" href=\"https:\/\/depts.washington.edu\/pandemicalliance\/2020\/08\/12\/strategic-anti-sars-cov-2-serology-testing-in-a-low-prevalence-pandemic-the-covid-19-contact-coco-study-in-health-care-professionals\/\">Read more<\/a><\/div>\n","protected":false},"author":8,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":"","_links_to":"","_links_to_target":""},"categories":[6],"tags":[],"topic":[20],"class_list":["post-9010","post","type-post","status-publish","format-standard","hentry","category-article-summary","topic-clinical-characteristics-and-health-care-setting"],"_links":{"self":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/9010","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/users\/8"}],"replies":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/comments?post=9010"}],"version-history":[{"count":1,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/9010\/revisions"}],"predecessor-version":[{"id":9011,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/9010\/revisions\/9011"}],"wp:attachment":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/media?parent=9010"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/categories?post=9010"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/tags?post=9010"},{"taxonomy":"topic","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/topic?post=9010"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}