{"id":9012,"date":"2020-08-12T11:19:26","date_gmt":"2020-08-12T18:19:26","guid":{"rendered":"https:\/\/depts.washington.edu\/pandemicalliance\/?p=9012"},"modified":"2021-04-13T11:19:58","modified_gmt":"2021-04-13T18:19:58","slug":"association-of-mental-disorders-with-sars-cov-2-infection-and-severe-health-outcomes-a-nationwide-cohort-study","status":"publish","type":"post","link":"https:\/\/depts.washington.edu\/pandemicalliance\/2020\/08\/12\/association-of-mental-disorders-with-sars-cov-2-infection-and-severe-health-outcomes-a-nationwide-cohort-study\/","title":{"rendered":"Association of Mental Disorders with SARS-CoV-2 Infection and Severe Health Outcomes a Nationwide Cohort Study"},"content":{"rendered":"<ul>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"2\" data-aria-posinset=\"1\" data-aria-level=\"1\"><i><span data-contrast=\"none\">[pre-print, not peer-reviewed]<\/span><\/i><span data-contrast=\"auto\">\u00a0<\/span><span data-contrast=\"auto\">A matched (age, sex, Charlson comorbidity index) cohort study of individuals tested for COVID-19 in Korea (n=<\/span><span data-contrast=\"auto\">122,722) found no evidence of association between a diagnosis of mental illness in the preceding 6 months and COVID-19 test positivity<\/span><span data-contrast=\"auto\">. A<\/span><span data-contrast=\"auto\">\u00a0subgroup analyses found those with schizophrenia-related disorders had a higher\u00a0<\/span><span data-contrast=\"auto\">likelihood of\u00a0<\/span><span data-contrast=\"auto\">test positivity (<\/span><span data-contrast=\"auto\">OR=<\/span><span data-contrast=\"auto\">1.36, 95%CI 1.02-1.81).<\/span><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"2\" data-aria-posinset=\"2\" data-aria-level=\"1\"><span data-contrast=\"auto\">Restricted to a matched sub-cohort of confirmed cases (n=3,608), mental illness was associated with a significantly higher\u00a0<\/span><span data-contrast=\"auto\">likelihood\u00a0<\/span><span data-contrast=\"auto\">of death (<\/span><span data-contrast=\"auto\">OR=<\/span><span data-contrast=\"auto\">1.84, 95%CI 2.07-3.15) and non-significantly higher\u00a0<\/span><span data-contrast=\"auto\">likelihood\u00a0<\/span><span data-contrast=\"auto\">of severe illness (<\/span><span data-contrast=\"auto\">OR=<\/span><span data-contrast=\"auto\">1.17, 95% CI 0.76-1.81).\u00a0<\/span><span data-contrast=\"auto\">A sensitivity analysis indicated that\u00a0<\/span><span data-contrast=\"auto\">an alternative explanation for the observed relationship between mental illness and death<\/span><span data-contrast=\"auto\">\u00a0<\/span><span data-contrast=\"auto\">due to\u00a0<\/span><span data-contrast=\"auto\">unmeasured confounding\u00a0<\/span><span data-contrast=\"auto\">factors was unlikely.<\/span><span data-contrast=\"auto\">\u00a0<\/span><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li>\n<\/ul>\n<p><i><span data-contrast=\"none\">Jeon et al. (Aug 7, 2020). Association of Mental Disorders with SARS-CoV-2 Infection and Severe Health Outcomes a Nationwide Cohort Study.\u00a0<\/span><\/i><i><span data-contrast=\"none\">Pre-print\u00a0downloaded\u00a0Aug 12 from<\/span><\/i><i><span data-contrast=\"none\">\u00a0<\/span><\/i><a href=\"https:\/\/doi.org\/10.1101\/2020.08.05.20169201\"><span data-contrast=\"none\">https:\/\/doi.org\/10.1101\/2020.08.05.20169201<\/span><\/a><span data-ccp-props=\"{&quot;201341983&quot;:0,&quot;335559685&quot;:720,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"<p>[pre-print, not peer-reviewed]\u00a0A matched (age, sex, Charlson comorbidity index) cohort study of individuals tested for COVID-19 in Korea (n=122,722) found no evidence of association between a diagnosis of mental illness in the preceding 6 months and COVID-19 test positivity. A\u00a0subgroup analyses found those with schizophrenia-related disorders had a higher\u00a0likelihood of\u00a0test positivity (OR=1.36, 95%CI 1.02-1.81).\u00a0 Restricted&#8230;<\/p>\n<div><a class=\"more\" href=\"https:\/\/depts.washington.edu\/pandemicalliance\/2020\/08\/12\/association-of-mental-disorders-with-sars-cov-2-infection-and-severe-health-outcomes-a-nationwide-cohort-study\/\">Read more<\/a><\/div>\n","protected":false},"author":8,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":"","_links_to":"","_links_to_target":""},"categories":[6],"tags":[],"topic":[20],"class_list":["post-9012","post","type-post","status-publish","format-standard","hentry","category-article-summary","topic-clinical-characteristics-and-health-care-setting"],"_links":{"self":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/9012","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/users\/8"}],"replies":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/comments?post=9012"}],"version-history":[{"count":1,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/9012\/revisions"}],"predecessor-version":[{"id":9013,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/9012\/revisions\/9013"}],"wp:attachment":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/media?parent=9012"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/categories?post=9012"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/tags?post=9012"},{"taxonomy":"topic","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/topic?post=9012"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}