{"id":9073,"date":"2020-08-17T11:45:51","date_gmt":"2020-08-17T18:45:51","guid":{"rendered":"https:\/\/depts.washington.edu\/pandemicalliance\/?p=9073"},"modified":"2021-04-13T11:58:05","modified_gmt":"2021-04-13T18:58:05","slug":"covid-19-literature-situation-report-august-17-2020","status":"publish","type":"post","link":"https:\/\/depts.washington.edu\/pandemicalliance\/2020\/08\/17\/covid-19-literature-situation-report-august-17-2020\/","title":{"rendered":"COVID-19 Literature Situation Report August 17, 2020"},"content":{"rendered":"<p>The scientific literature on COVID-19 is rapidly evolving and these articles were selected for review based on their relevance to Washington State decision making around COVID-19 response efforts. Included in these Lit Reps are some manuscripts that have been made available online as pre-prints but have not yet undergone peer review. Please be aware of this when reviewing articles included in the Lit Reps.<\/p>\n<h2>Key Takeaways<\/h2>\n<ul>\n<li><b><span data-contrast=\"auto\">Utah reported 1,389 COVID-19 cases associated with 210 workplace-related outbreaks<\/span><\/b><b><span data-contrast=\"auto\">\u00a0d<\/span><\/b><b><span data-contrast=\"auto\">uring March 6\u2013June 5, 2020<\/span><\/b><b><span data-contrast=\"auto\">, which occurred most commonly in the areas of m<\/span><\/b><b><span data-contrast=\"auto\">anufacturing (20%),\u00a0<\/span><\/b><b><span data-contrast=\"auto\">c<\/span><\/b><b><span data-contrast=\"auto\">onstruction\u00a0<\/span><\/b><b><span data-contrast=\"auto\">(15%), and\u00a0<\/span><\/b><b><span data-contrast=\"auto\">w<\/span><\/b><b><span data-contrast=\"auto\">holesale\u00a0<\/span><\/b><b><span data-contrast=\"auto\">t<\/span><\/b><b><span data-contrast=\"auto\">rade\u00a0<\/span><\/b><b><span data-contrast=\"auto\">(14%). Hispanic and nonwhite workers accounted for\u00a0<\/span><\/b><b><span data-contrast=\"auto\">a large disproportional number of\u00a0<\/span><\/b><b><span data-contrast=\"auto\">workplace outbreak-associated COVID-19 cases.<\/span><\/b><span data-contrast=\"auto\">\u00a0<\/span><a href=\"https:\/\/doi.org\/10.15585\/mmwr.mm6933e3\"><span data-contrast=\"none\">More<\/span><\/a><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li>\n<li data-leveltext=\"\uf0d8\" data-font=\"Wingdings\" data-listid=\"1\" data-aria-posinset=\"1\" data-aria-level=\"1\"><b><span data-contrast=\"auto\">No excess mortality\u00a0<\/span><\/b><b><span data-contrast=\"auto\">was identified among\u00a0<\/span><\/b><b><span data-contrast=\"auto\">children\u00a0<\/span><\/b><b><span data-contrast=\"auto\">in England\u00a0<\/span><\/b><b><span data-contrast=\"auto\">based on<\/span><\/b><b><span data-contrast=\"auto\">\u00a0<\/span><\/b><b><span data-contrast=\"auto\">death registration\u00a0<\/span><\/b><b><span data-contrast=\"auto\">data through May 3<\/span><\/b><b><span data-contrast=\"auto\">, 2020<\/span><\/b><b><span data-contrast=\"auto\">\u00a0and\u00a0<\/span><\/b><b><span data-contrast=\"auto\">surveillance data indicated that\u00a0<\/span><\/b><b><span data-contrast=\"auto\">the\u00a0<\/span><\/b><b><span data-contrast=\"auto\">SARS-CoV-2\u00a0<\/span><\/b><b><span data-contrast=\"auto\">test positivity rate was markedly lower in children than\u00a0<\/span><\/b><b><span data-contrast=\"auto\">in<\/span><\/b><b><span data-contrast=\"auto\">\u00a0adults<\/span><\/b><b><span data-contrast=\"auto\">\u00a0(4% versus\u00a0<\/span><\/b><b><span data-contrast=\"auto\">19%-35%<\/span><\/b><b><span data-contrast=\"auto\">)<\/span><\/b><b><span data-contrast=\"auto\">.<\/span><\/b><span data-contrast=\"auto\">\u00a0<\/span><a href=\"https:\/\/doi.org\/10.1136\/archdischild-2020-320042\"><span data-contrast=\"none\">More<\/span><\/a><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li>\n<li data-leveltext=\"\uf0d8\" data-font=\"Wingdings\" data-listid=\"1\" data-aria-posinset=\"2\" data-aria-level=\"1\"><b><span data-contrast=\"auto\">A modeling study focused on King County in Washington State predicts that\u00a0<\/span><\/b><b><span data-contrast=\"auto\">returning\u00a0<\/span><\/b><b><span data-contrast=\"auto\">only\u00a0<\/span><\/b><b><span data-contrast=\"auto\">elementary schools to in-person<\/span><\/b><b><span data-contrast=\"auto\">\u00a0<\/span><\/b><b><span data-contrast=\"auto\">instruction<\/span><\/b><b><span data-contrast=\"auto\">\u00a0on an A\/B 2-day a week schedule would\u00a0<\/span><\/b><b><span data-contrast=\"auto\">result in a<\/span><\/b><b><span data-contrast=\"auto\">\u00a0cumulative risk of COVID infection in students, staff and teachers\u00a0<\/span><\/b><b><span data-contrast=\"auto\">of<\/span><\/b><b><span data-contrast=\"auto\">\u00a0below<\/span><\/b><b><span data-contrast=\"auto\">\u00a0<\/span><\/b><b><span data-contrast=\"auto\">1.2%<\/span><\/b><b><span data-contrast=\"auto\">.<\/span><\/b><span data-contrast=\"auto\">\u00a0<\/span><a href=\"https:\/\/covid.idmod.org\/data\/Maximizing_education_while_minimizing_COVID_risk.pdf\"><span data-contrast=\"none\">More<\/span><\/a><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li>\n<li data-leveltext=\"\uf0d8\" data-font=\"Wingdings\" data-listid=\"1\" data-aria-posinset=\"3\" data-aria-level=\"1\"><b><span data-contrast=\"auto\">Among\u00a0<\/span><\/b><b><span data-contrast=\"auto\">76\u00a0<\/span><\/b><b><span data-contrast=\"auto\">COVID-19<\/span><\/b><b><span data-contrast=\"auto\">\u00a0<\/span><\/b><b><span data-contrast=\"auto\">hotspot counties in\u00a0<\/span><\/b><b><span data-contrast=\"auto\">the\u00a0<\/span><\/b><b><span data-contrast=\"auto\">US<\/span><\/b><b><span data-contrast=\"auto\">,\u00a0<\/span><\/b><b><span data-contrast=\"auto\">there was\u00a0<\/span><\/b><b><span data-contrast=\"auto\">disproportionate<\/span><\/b><b><span data-contrast=\"auto\">ly high<\/span><\/b><b><span data-contrast=\"auto\">\u00a0incidence of COVID-19\u00a0<\/span><\/b><b><span data-contrast=\"auto\">cases\u00a0<\/span><\/b><b><span data-contrast=\"auto\">among underrepresented racial\/ethnic groups.<\/span><\/b><span data-contrast=\"auto\">\u00a0<\/span><a href=\"https:\/\/doi.org\/10.15585\/mmwr.mm6933e1\"><span data-contrast=\"none\">More<\/span><\/a><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li>\n<\/ul>\n<div id=\"uw-accordion-shortcode\">\n<h3>Article Summaries<\/h3>\n<div class=\"js-accordion\" data-accordion-prefix-classes=\"uw-accordion-shortcode\">\n<div class=\"js-accordion__panel\" >\n<h2 class=\"js-accordion__header\"><span class=\"TextRun SCXW70641427 BCX0\" lang=\"EN-US\" xml:lang=\"EN-US\" data-contrast=\"none\"><span class=\"NormalTextRun SCXW70641427 BCX0\" data-ccp-parastyle=\"heading 2\">Transmission<\/span><\/span><\/h2>\n<div class=\"su-posts su-posts-default-loop\">\n<div id=\"su-post-9077\" class=\"su-post\">\n<h5 class=\"su-post-title\">Disparities in Incidence of COVID-19 Among Underrepresented Racial\/Ethnic Groups in Counties Identified as Hotspots During June 5\u201318, 2020 \u2014 22 States, February\u2013June 2020<\/h5>\n<p>\t\t\t\t<!-- \n\n\n\n\n\n\n\n\n\n\n\n<div class=\"su-post-meta\">\n\t\t\t\t\t: \t\t\t\t<\/div>\n\n\n\n\n\n\n\n\n\n\n\n --><\/p>\n<div class=\"su-post-excerpt\">\n<ul>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"34\" data-aria-posinset=\"2019\" data-aria-level=\"1\"><span data-contrast=\"auto\">Moore et al. calculated the\u00a0<\/span><span data-contrast=\"auto\">disparities in COVID-19 cases among underrepresented racial\/ethnic groups in 76 counties\u00a0<\/span><span data-contrast=\"auto\">in<\/span><span data-contrast=\"auto\">\u00a022 US states identified as hotspots during June 5\u201318, 2020.\u00a0<\/span><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"34\" data-aria-posinset=\"2019\" data-aria-level=\"1\"><span data-contrast=\"auto\">They report<\/span><span data-contrast=\"auto\">\u00a0that\u00a0<\/span><span data-contrast=\"auto\">76 (96%) analyzed hotspot counties had disparities in cases identified among underrepresented racial\/ethnic groups during February\u2013June 2020: 59 (75%) counties had disparities among Hispanic residents; 22 (28%) among black residents; 3 (4%) among American Indian\/Alaska Native\u202f(AI\/AN) residents; 4 (5%) among Asian residents; and 19 (24%) among Native Hawaiian\/other Pacific Islander (NPHI) residents.<\/span><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li>\n<\/ul>\n<p><i><span data-contrast=\"none\">Moore et al. (Aug 14, 2020). Disparities in Incidence of COVID-19 Among Underrepresented Racial\/Ethnic Groups in Counties Identified as Hotspots During June 5\u201318, 2020 \u2014 22 States, February\u2013June 2020. MMWR.\u00a0<\/span><\/i><a href=\"https:\/\/doi.org\/10.15585\/mmwr.mm6933e1\"><span data-contrast=\"none\">https:\/\/doi.org\/10.15585\/mmwr.mm6933e1<\/span><\/a><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559685&quot;:720,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/p>\n<\/p>\n<\/div>\n<p>\t\t\t\t\t\t\t\t\t<!-- <a href=\"\" class=\"su-post-comments-link\"><\/a> --><\/p>\n<\/div>\n<div id=\"su-post-9075\" class=\"su-post\">\n<h5 class=\"su-post-title\">Racial and Ethnic Disparities Among COVID-19 Cases in Workplace Outbreaks by Industry Sector \u2014 Utah, March 6\u2013June 5, 2020<\/h5>\n<p>\t\t\t\t<!-- \n\n\n\n\n\n\n\n\n\n\n\n<div class=\"su-post-meta\">\n\t\t\t\t\t: \t\t\t\t<\/div>\n\n\n\n\n\n\n\n\n\n\n\n --><\/p>\n<div class=\"su-post-excerpt\">\n<ul>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"34\" data-aria-posinset=\"2019\" data-aria-level=\"1\"><span data-contrast=\"auto\">During March 6\u2013June 5, 2020, Utah reported 1,389 COVID-19 cases associated with 210 workplace-related outbreaks, defined as the occurrence of two or more laboratory-confirmed cases occurring within the same 14-day period among coworkers in a common workplace (median cases per outbreak=4; range=2\u201379) involving 15 industry sectors, most frequently in\u00a0<\/span><span data-contrast=\"auto\">m<\/span><span data-contrast=\"auto\">anufacturing (20%),\u00a0<\/span><span data-contrast=\"auto\">c<\/span><span data-contrast=\"auto\">onstruction (15%), and\u00a0<\/span><span data-contrast=\"auto\">w<\/span><span data-contrast=\"auto\">holesale\u00a0<\/span><span data-contrast=\"auto\">t<\/span><span data-contrast=\"auto\">rade (14%). In total, 970 (73%) of persons with workplace outbreak-associated COVID-19 were identified as Hispanic or nonwhite, although these ethnic\/racial groups represent &lt;24% of Utah\u2019s workforce in the 15 affected industry sectors.\u00a0<\/span><span data-contrast=\"auto\">The authors conclude that\u00a0<\/span><span data-contrast=\"auto\">mitigation strategies should be culturally and linguistically responsive to racial\/ethnic minority workers disproportionately affected by COVID-19.<\/span><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li>\n<\/ul>\n<p><i><span data-contrast=\"none\">Bui et al. (<\/span><\/i><i><span data-contrast=\"none\">Aug 17,\u00a0<\/span><\/i><i><span data-contrast=\"none\">2020). Racial and Ethnic Disparities Among COVID-19 Cases in Workplace Outbreaks by Industry Sector \u2014 Utah, March 6\u2013June 5, 2020. MMWR.\u00a0<\/span><\/i><a href=\"https:\/\/doi.org\/10.15585\/mmwr.mm6933e3\"><span data-contrast=\"none\">https:\/\/doi.org\/10.15585\/mmwr.mm6933e3<\/span><\/a><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559685&quot;:720,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/p>\n<\/p>\n<\/div>\n<p>\t\t\t\t\t\t\t\t\t<!-- <a href=\"\" class=\"su-post-comments-link\"><\/a> --><\/p>\n<\/div>\n<\/div>\n<\/div>\n<div class=\"js-accordion__panel\" >\n<h2 class=\"js-accordion__header\"><span class=\"TextRun SCXW173333515 BCX0\" lang=\"EN-US\" xml:lang=\"EN-US\" data-contrast=\"none\"><span class=\"NormalTextRun SCXW173333515 BCX0\" data-ccp-parastyle=\"heading 2\">Testing and Treatment<\/span><\/span><\/h2>\n<div class=\"su-posts su-posts-default-loop\">\n<div id=\"su-post-9081\" class=\"su-post\">\n<h5 class=\"su-post-title\">Tocilizumab among Patients with COVID-19 in the Intensive Care Unit: A\u00a0Multicentre\u00a0Observational Study<\/h5>\n<p>\t\t\t\t<!-- \n\n\n\n\n\n\n\n\n\n\n\n<div class=\"su-post-meta\">\n\t\t\t\t\t: \t\t\t\t<\/div>\n\n\n\n\n\n\n\n\n\n\n\n --><\/p>\n<div class=\"su-post-excerpt\">\n<ul>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"34\" data-aria-posinset=\"2019\" data-aria-level=\"1\"><span data-contrast=\"auto\">Based on<\/span><span data-contrast=\"auto\">\u00a0210 patients with laboratory-confirmed COVID-19<\/span><span data-contrast=\"auto\">\u00a0<\/span><span data-contrast=\"auto\">in\u00a0<\/span><span data-contrast=\"auto\">ICUs in\u00a0<\/span><span data-contrast=\"auto\">New Jersey,\u00a0<\/span><span data-contrast=\"auto\">r<\/span><span data-contrast=\"auto\">eceiving\u00a0<\/span><span data-contrast=\"auto\">the drug\u00a0<\/span><span data-contrast=\"auto\">tocilizumab was associated with a\u00a0<\/span><span data-contrast=\"auto\">40% reduction in\u00a0<\/span><span data-contrast=\"auto\">mortality (<\/span><span data-contrast=\"auto\">a<\/span><span data-contrast=\"auto\">HR<\/span><span data-contrast=\"auto\">=<\/span><span data-contrast=\"auto\">0.6, 95%CI 0.5-0.9)<\/span><span data-contrast=\"auto\">\u00a0<\/span><span data-contrast=\"auto\">compared\u00a0<\/span><span data-contrast=\"auto\">with\u00a0<\/span><span data-contrast=\"auto\">420 propensity score-matched patients who did not receive tocilizumab.<\/span><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li>\n<\/ul>\n<p><i><span data-contrast=\"none\">Biran<\/span><\/i><i><span data-contrast=\"none\">\u00a0et al. (Aug 14, 2020). Tocilizumab among Patients with COVID-19 in the Intensive Care Unit: A\u00a0<\/span><\/i><i><span data-contrast=\"none\">Multicentre<\/span><\/i><i><span data-contrast=\"none\">\u00a0Observational Study. The Lancet Rheumatology.\u00a0<\/span><\/i><a href=\"https:\/\/doi.org\/10.1016\/S2665-9913(20)30277-0\"><span data-contrast=\"none\">https:\/\/doi.org\/10.1016\/S2665-9913(20)30277-0<\/span><\/a><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559685&quot;:720,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/p>\n<\/p>\n<\/div>\n<p>\t\t\t\t\t\t\t\t\t<!-- <a href=\"\" class=\"su-post-comments-link\"><\/a> --><\/p>\n<\/div>\n<div id=\"su-post-9079\" class=\"su-post\">\n<h5 class=\"su-post-title\">COVID-19 in Children: Analysis of the First Pandemic Peak in England<\/h5>\n<p>\t\t\t\t<!-- \n\n\n\n\n\n\n\n\n\n\n\n<div class=\"su-post-meta\">\n\t\t\t\t\t: \t\t\t\t<\/div>\n\n\n\n\n\n\n\n\n\n\n\n --><\/p>\n<div class=\"su-post-excerpt\">\n<ul>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"34\" data-aria-posinset=\"2019\" data-aria-level=\"1\"><span data-contrast=\"auto\">Ladhani<\/span><span data-contrast=\"auto\">\u00a0et al.\u00a0<\/span><span data-contrast=\"auto\">analyzed\u00a0<\/span><span data-contrast=\"auto\">public health surveillance\u00a0<\/span><span data-contrast=\"auto\">data\u00a0<\/span><span data-contrast=\"auto\">including<\/span><span data-contrast=\"auto\">\u00a0<\/span><span data-contrast=\"auto\">540,305<\/span><span data-contrast=\"auto\">\u00a0people\u00a0<\/span><span data-contrast=\"auto\">tested for SAR<\/span><span data-contrast=\"auto\">S<\/span><span data-contrast=\"auto\">-CoV-2 in Eng<\/span><span data-contrast=\"auto\">land\u00a0<\/span><span data-contrast=\"auto\">through May 3<\/span><span data-contrast=\"auto\">, 2020<\/span><span data-contrast=\"auto\">\u00a0<\/span><span data-contrast=\"auto\">and found that 1408\/35,200 (4%) tests were positive among children\u00a0<\/span><span data-contrast=\"auto\">younger than 16<\/span><span data-contrast=\"auto\">,<\/span><span data-contrast=\"auto\">\u00a0compared to 19%-35%\u00a0<\/span><span data-contrast=\"auto\">positive\u00a0<\/span><span data-contrast=\"auto\">among adult age groups.<\/span><span data-contrast=\"auto\">\u00a0<\/span><span data-contrast=\"auto\">Children accounted for 1.1% of\u00a0<\/span><span data-contrast=\"auto\">SARS-CoV-2 positive cases<\/span><span data-contrast=\"auto\">.<\/span><span data-contrast=\"auto\">\u00a0<\/span><span data-contrast=\"auto\">These included\u00a0<\/span><span data-contrast=\"auto\">8 deaths among children, three of whom had multiple co-morbidities<\/span><span data-contrast=\"auto\">\u00a0and\u00a0<\/span><span data-contrast=\"auto\">an additional four in whom SARS-CoV-2 was determined to be an indirect contributor to death from another cause.\u00a0<\/span><span data-contrast=\"auto\">There was no\u00a0<\/span><span data-contrast=\"auto\">evidence of\u00a0<\/span><span data-contrast=\"auto\">excess\u00a0<\/span><span data-contrast=\"auto\">mortality<\/span><span data-contrast=\"auto\">\u00a0in children\u00a0<\/span><span data-contrast=\"auto\">during this period<\/span><span data-contrast=\"auto\">.\u00a0<\/span><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li>\n<\/ul>\n<p><i><span data-contrast=\"none\">Ladhani<\/span><\/i><i><span data-contrast=\"none\">\u00a0et al. (Aug 12, 2020). COVID-19 in Children: Analysis of the First Pandemic Peak in England. Archives of Disease in Childhood.\u00a0<\/span><\/i><a href=\"https:\/\/doi.org\/10.1136\/archdischild-2020-320042\"><span data-contrast=\"none\">https:\/\/doi.org\/10.1136\/archdischild-2020-320042<\/span><\/a><span data-ccp-props=\"{&quot;201341983&quot;:0,&quot;335559685&quot;:720,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/p>\n<\/p>\n<\/div>\n<p>\t\t\t\t\t\t\t\t\t<!-- <a href=\"\" class=\"su-post-comments-link\"><\/a> --><\/p>\n<\/div>\n<\/div>\n<\/div>\n<div class=\"js-accordion__panel\" >\n<h2 class=\"js-accordion__header\"><span class=\"TextRun SCXW173333515 BCX0\" lang=\"EN-US\" xml:lang=\"EN-US\" data-contrast=\"none\"><span class=\"NormalTextRun SCXW173333515 BCX0\" data-ccp-parastyle=\"heading 2\">Immunity<\/span><\/span><\/h2>\n<div class=\"su-posts su-posts-default-loop\">\n<div id=\"su-post-9083\" class=\"su-post\">\n<h5 class=\"su-post-title\">Pre-COVID-19 Humoral Immunity to Common Coronaviruses Does Not Confer Cross-Protection against SARS-CoV-2<\/h5>\n<p>\t\t\t\t<!-- \n\n\n\n\n\n\n\n\n\n\n\n<div class=\"su-post-meta\">\n\t\t\t\t\t: \t\t\t\t<\/div>\n\n\n\n\n\n\n\n\n\n\n\n --><\/p>\n<div class=\"su-post-excerpt\">\n<ul>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"45\" data-aria-posinset=\"1\" data-aria-level=\"1\"><i><span data-contrast=\"none\">[Preprint, not peer-reviewed]\u00a0<\/span><\/i><span data-contrast=\"auto\">Miyara<\/span><span data-contrast=\"auto\">\u00a0et al. analyzed the sera of 76 healthy French donors drawn in 2015 to test the hypothesis that past infections or immunizations related to the common alpha- and beta-coronavirus could lead to cross-protecti<\/span><span data-contrast=\"auto\">on against SARS-CoV-2. They reported 6 serological samples (<\/span><span data-contrast=\"auto\">8<\/span><span data-contrast=\"auto\">%) were reactive to SARS-CoV-2 antigens.\u00a0<\/span><span data-contrast=\"auto\">Additionally<\/span><span data-contrast=\"auto\">, they detected serum IgG reactivity to common coronaviruses in the early sera of 8 patients with severe COVID-19 before the appearance of anti-SARS-CoV-2 antibodies. The authors<\/span><span data-contrast=\"auto\">\u00a0concluded that pre-existing immunity to common coronaviruses does not confer cross-protection against SARS-CoV-2.<\/span><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559685&quot;:360,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li>\n<\/ul>\n<p><i><span data-contrast=\"none\">Miyara<\/span><\/i><i><span data-contrast=\"none\">\u00a0et al. (Aug 15, 2020). Pre-COVID-19 Humoral Immunity to Common Coronaviruses Does Not Confer Cross-Protection against SARS-CoV-2. Pre-print downloaded Aug 17 from\u00a0<\/span><\/i><a href=\"https:\/\/doi.org\/10.1101\/2020.08.14.20173393\"><span data-contrast=\"none\">https:\/\/doi.org\/10.1101\/2020.08.14.20173393<\/span><\/a><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559685&quot;:720,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/p>\n<\/p>\n<\/div>\n<p>\t\t\t\t\t\t\t\t\t<!-- <a href=\"\" class=\"su-post-comments-link\"><\/a> --><\/p>\n<\/div>\n<\/div>\n<\/div>\n<div class=\"js-accordion__panel\" >\n<h2 class=\"js-accordion__header\"><span class=\"TextRun SCXW22351167 BCX0\" lang=\"EN-US\" xml:lang=\"EN-US\" data-contrast=\"none\"><span class=\"NormalTextRun SCXW22351167 BCX0\" data-ccp-parastyle=\"heading 2\">Clinical Characteristics<\/span><\/span><span class=\"TextRun SCXW22351167 BCX0\" lang=\"EN-US\" xml:lang=\"EN-US\" data-contrast=\"none\"><span class=\"NormalTextRun SCXW22351167 BCX0\" data-ccp-parastyle=\"heading 2\"> and Health Care Setting<\/span><\/span><\/h2>\n<div class=\"su-posts su-posts-default-loop\">\n<div id=\"su-post-9085\" class=\"su-post\">\n<h5 class=\"su-post-title\">Cerebral Micro-Structural Changes in COVID-19 Patients \u2013 An MRI-Based 3-Month Follow-up Study<\/h5>\n<p>\t\t\t\t<!-- \n\n\n\n\n\n\n\n\n\n\n\n<div class=\"su-post-meta\">\n\t\t\t\t\t: \t\t\t\t<\/div>\n\n\n\n\n\n\n\n\n\n\n\n --><\/p>\n<div class=\"su-post-excerpt\">\n<ul>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"34\" data-aria-posinset=\"2019\" data-aria-level=\"1\"><span data-contrast=\"auto\">A study of\u00a0<\/span><span data-contrast=\"auto\">p<\/span><span data-contrast=\"auto\">atients\u00a0<\/span><span data-contrast=\"auto\">with\u00a0<\/span><span data-contrast=\"auto\">COVID-19\u00a0<\/span><span data-contrast=\"auto\">(n=60)\u00a0<\/span><span data-contrast=\"auto\">in\u00a0<\/span><span data-contrast=\"auto\">Fuyang<\/span><span data-contrast=\"auto\">, China\u00a0<\/span><span data-contrast=\"auto\">found that 68% had neurological symptoms during infection and 55% still had\u00a0<\/span><span data-contrast=\"auto\">symptoms 3 months after\u00a0<\/span><span data-contrast=\"auto\">infection.\u00a0<\/span><span data-contrast=\"auto\">Brain imaging identified a\u00a0<\/span><span data-contrast=\"auto\">variety of significantly different neurological characteristics between COVID-19 patients and non-COVID-19 volunteers\u00a0<\/span><span data-contrast=\"auto\">(n=39)<\/span><span data-contrast=\"auto\">\u00a0<\/span><span data-contrast=\"auto\">that could be relevant to<\/span><span data-contrast=\"auto\">\u00a0long-term consequences of SARS-CoV-2.<\/span><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li>\n<\/ul>\n<p><i><span data-contrast=\"none\">Lu et al. (Aug 3, 2020). Cerebral Micro-Structural Changes in COVID-19 Patients \u2013 An MRI-Based 3-Month Follow-up Study.\u00a0<\/span><\/i><i><span data-contrast=\"none\">EClinicalMedicine<\/span><\/i><i><span data-contrast=\"none\">.\u00a0<\/span><\/i><a href=\"https:\/\/doi.org\/10.1016\/j.eclinm.2020.100484\"><span data-contrast=\"none\">https:\/\/doi.org\/10.1016\/j.eclinm.2020.100484<\/span><\/a><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559685&quot;:720,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/p>\n<\/p>\n<\/div>\n<p>\t\t\t\t\t\t\t\t\t<!-- <a href=\"\" class=\"su-post-comments-link\"><\/a> --><\/p>\n<\/div>\n<\/div>\n<\/div>\n<div class=\"js-accordion__panel\" >\n<h2 class=\"js-accordion__header\"><span class=\"TextRun BCX0 SCXW227321329\" lang=\"EN-US\" xml:lang=\"EN-US\" data-contrast=\"none\"><span class=\"NormalTextRun BCX0 SCXW227321329\" data-ccp-parastyle=\"heading 2\"><span class=\"TextRun SCXW53176017 BCX0\" lang=\"EN-US\" xml:lang=\"EN-US\" data-contrast=\"none\"><span class=\"NormalTextRun SCXW53176017 BCX0\" data-ccp-parastyle=\"heading 2\">Mental Health a<\/span><\/span><span class=\"TextRun SCXW53176017 BCX0\" lang=\"EN-US\" xml:lang=\"EN-US\" data-contrast=\"none\"><span class=\"NormalTextRun SCXW53176017 BCX0\" data-ccp-parastyle=\"heading 2\">nd Personal Impact<\/span><\/span><\/span><\/span><\/h2>\n<div class=\"su-posts su-posts-default-loop\">\n<div id=\"su-post-9089\" class=\"su-post\">\n<h5 class=\"su-post-title\">Bidirectional Associations between COVID-19 and Psychiatric Disorder a Study of 62354 COVID-19 Cases<\/h5>\n<p>\t\t\t\t<!-- \n\n\n\n\n\n\n\n\n\n\n\n<div class=\"su-post-meta\">\n\t\t\t\t\t: \t\t\t\t<\/div>\n\n\n\n\n\n\n\n\n\n\n\n --><\/p>\n<div class=\"su-post-excerpt\">\n<ul>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"34\" data-aria-posinset=\"2019\" data-aria-level=\"1\"><i><span data-contrast=\"none\">[<\/span><\/i><i><span data-contrast=\"none\">Preprint<\/span><\/i><i><span data-contrast=\"none\">, not peer-reviewed]<\/span><\/i><i><span data-contrast=\"none\">\u00a0<\/span><\/i><span data-contrast=\"auto\">Taquet<\/span><span data-contrast=\"auto\">\u00a0et al. used\u00a0<\/span><span data-contrast=\"auto\">anonymized electronic health record data from\u00a0<\/span><span data-contrast=\"auto\">69 million patients<\/span><span data-contrast=\"auto\">\u00a0in the US,<\/span><span data-contrast=\"auto\">\u00a0including over 62,000 cases of COVID-19<\/span><span data-contrast=\"auto\">,\u00a0<\/span><span data-contrast=\"auto\">to\u00a0<\/span><span data-contrast=\"auto\">identify\u00a0<\/span><span data-contrast=\"auto\">relationships<\/span><span data-contrast=\"auto\">\u00a0between COVID-19\u00a0<\/span><span data-contrast=\"auto\">episodes<\/span><span data-contrast=\"auto\">\u00a0<\/span><span data-contrast=\"auto\">and adverse mental health consequences.\u00a0<\/span><span data-contrast=\"auto\">They report that among patients with no prior psychiatric history, COVID-19 was associated with an increased incidence of psychiatric diagnoses in the three months after infection compared to other health events (HR range 1.6-2.2). A psychiatric diagnosis in the previous year was associated with a 65% higher incidence of COVID-19 (p&lt;0.001).\u00a0<\/span><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li>\n<\/ul>\n<p><i><span data-contrast=\"none\">Taquet<\/span><\/i><i><span data-contrast=\"none\">\u00a0et al. (Aug 16, 2020). Bidirectional Associations between COVID-19 and Psychiatric Disorder a Study of 62354 COVID-19 Cases. Pre-print downloaded Aug 17 from\u00a0<\/span><\/i><a href=\"https:\/\/doi.org\/10.1101\/2020.08.14.20175190\"><span data-contrast=\"none\">https:\/\/doi.org\/10.1101\/2020.08.14.20175190<\/span><\/a><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559685&quot;:720,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/p>\n<\/p>\n<\/div>\n<p>\t\t\t\t\t\t\t\t\t<!-- <a href=\"\" class=\"su-post-comments-link\"><\/a> --><\/p>\n<\/div>\n<div id=\"su-post-9087\" class=\"su-post\">\n<h5 class=\"su-post-title\">Association Between Current Physical Activity and Current Perceived Anxiety and Mood in the Initial Phase of COVID-19 Confinement<\/h5>\n<p>\t\t\t\t<!-- \n\n\n\n\n\n\n\n\n\n\n\n<div class=\"su-post-meta\">\n\t\t\t\t\t: \t\t\t\t<\/div>\n\n\n\n\n\n\n\n\n\n\n\n --><\/p>\n<div class=\"su-post-excerpt\">\n<ul>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"34\" data-aria-posinset=\"2019\" data-aria-level=\"1\"><span data-contrast=\"auto\">L\u00f3pez-Bueno et al. observed\u00a0<\/span><span data-contrast=\"auto\">that among\u00a0<\/span><span data-contrast=\"auto\">2,250 Spanish adults confined due to COVID-19 restrictions\u00a0<\/span><span data-contrast=\"auto\">on<\/span><span data-contrast=\"auto\">\u00a0movement\u00a0<\/span><span data-contrast=\"auto\">(<\/span><span data-contrast=\"auto\">March 22-29, 2020<\/span><span data-contrast=\"auto\">), those who\u00a0<\/span><span data-contrast=\"auto\">adher<\/span><span data-contrast=\"auto\">ed<\/span><span data-contrast=\"auto\">\u00a0to WHO guidelines\u00a0<\/span><span data-contrast=\"auto\">for physical activity reported<\/span><span data-contrast=\"auto\">\u00a0lower perceived anxiety and lower perceived worse mood<\/span><span data-contrast=\"auto\">.<\/span><span data-contrast=\"auto\">\u00a0<\/span><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li>\n<\/ul>\n<p><i><span data-contrast=\"none\">L\u00f3pez-Bueno et al. (July 23, 2020). Association Between Current Physical Activity and Current Perceived Anxiety and Mood in the Initial Phase of COVID-19 Confinement. Frontiers in Psychiatry.\u00a0<\/span><\/i><a href=\"https:\/\/doi.org\/10.3389\/fpsyt.2020.00729\"><span data-contrast=\"none\">https:\/\/doi.org\/10.3389\/fpsyt.2020.00729<\/span><\/a><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559685&quot;:720,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/p>\n<\/p>\n<\/div>\n<p>\t\t\t\t\t\t\t\t\t<!-- <a href=\"\" class=\"su-post-comments-link\"><\/a> --><\/p>\n<\/div>\n<\/div>\n<\/div>\n<div class=\"js-accordion__panel\" >\n<h2 class=\"js-accordion__header\"><span class=\"TextRun BCX0 SCXW227321329\" lang=\"EN-US\" xml:lang=\"EN-US\" data-contrast=\"none\"><span class=\"NormalTextRun BCX0 SCXW227321329\" data-ccp-parastyle=\"heading 2\">Mode<\/span><\/span><span class=\"TextRun BCX0 SCXW227321329\" lang=\"EN-US\" xml:lang=\"EN-US\" data-contrast=\"none\"><span class=\"NormalTextRun BCX0 SCXW227321329\" data-ccp-parastyle=\"heading 2\">ling and Prediction<\/span><\/span><\/h2>\n<div class=\"su-posts su-posts-default-loop\">\n<div id=\"su-post-9097\" class=\"su-post\">\n<h5 class=\"su-post-title\">The Common Interests of Health Protection and\u00a0The\u00a0Economy Evidence from Scenario Calculations Of COVID-19 Containment Policies<\/h5>\n<p>\t\t\t\t<!-- \n\n\n\n\n\n\n\n\n\n\n\n<div class=\"su-post-meta\">\n\t\t\t\t\t: \t\t\t\t<\/div>\n\n\n\n\n\n\n\n\n\n\n\n --><\/p>\n<div class=\"su-post-excerpt\">\n<ul>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"34\" data-aria-posinset=\"2019\" data-aria-level=\"1\"><i><span data-contrast=\"none\">[Preprint, not peer-reviewed]<\/span><\/i><span data-contrast=\"auto\">\u00a0<\/span><span data-contrast=\"auto\">Germany introduced restrictive shutdown measures in March 2020. The\u00a0<\/span><span data-contrast=\"auto\">reproductive rate (<\/span><span data-contrast=\"auto\">R<\/span><span data-contrast=\"auto\">t<\/span><span data-contrast=\"auto\">)\u00a0<\/span><span data-contrast=\"auto\">fell below one in April 14. On April 20th, a gradual loosening of the restrictions was announced. With a lag of two weeks R<\/span><span data-contrast=\"auto\">t<\/span><span data-contrast=\"auto\">\u00a0increased again at the beginning of May.<\/span><span data-contrast=\"auto\">\u00a0<\/span><span data-contrast=\"auto\">Based on these data during the initial shutdown phase,\u00a0<\/span><span data-contrast=\"auto\">Dorn et al. constructed a\u00a0<\/span><span data-contrast=\"auto\">simulation model to project the number of additional COVID-19 deaths until July 31st, 2021 with different scenarios of further loosening or tightening the shutdown measures.\u00a0<\/span><span data-contrast=\"auto\">T<\/span><span data-contrast=\"auto\">hey report that\u00a0<\/span><span data-contrast=\"auto\">a\u00a0<\/span><span data-contrast=\"auto\">gradual<\/span><span data-contrast=\"auto\">\u00a0<\/span><span data-contrast=\"auto\">opening<\/span><span data-contrast=\"auto\">\u00a0<\/span><span data-contrast=\"auto\">approach<\/span><span data-contrast=\"auto\">\u00a0is econ<\/span><span data-contrast=\"auto\">omically optimal, whereas costs are higher for a more extensive opening process.\u00a0<\/span><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li>\n<\/ul>\n<p><i><span data-contrast=\"none\">Dorn et al. (Aug 16, 2020). The Common Interests of Health Protection and\u00a0<\/span><\/i><i><span data-contrast=\"none\">The<\/span><\/i><i><span data-contrast=\"none\">\u00a0<\/span><\/i><i><span data-contrast=\"none\">Economy<\/span><\/i><i><span data-contrast=\"none\"> Evidence from Scenario Calculations Of COVID-19 Containment Policies. Pre-print downloaded Aug 17 from\u00a0<\/span><\/i><a href=\"https:\/\/doi.org\/10.1101\/2020.08.14.20175224\"><span data-contrast=\"none\">https:\/\/doi.org\/10.1101\/2020.08.14.20175224<\/span><\/a><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559685&quot;:720,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/p>\n<\/p>\n<\/div>\n<p>\t\t\t\t\t\t\t\t\t<!-- <a href=\"\" class=\"su-post-comments-link\"><\/a> --><\/p>\n<\/div>\n<div id=\"su-post-9095\" class=\"su-post\">\n<h5 class=\"su-post-title\">Vaccine Optimization for COVID-19 Who to Vaccinate First<\/h5>\n<p>\t\t\t\t<!-- \n\n\n\n\n\n\n\n\n\n\n\n<div class=\"su-post-meta\">\n\t\t\t\t\t: \t\t\t\t<\/div>\n\n\n\n\n\n\n\n\n\n\n\n --><\/p>\n<div class=\"su-post-excerpt\">\n<ul>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"34\" data-aria-posinset=\"2019\" data-aria-level=\"1\"><i><span data-contrast=\"none\">[<\/span><\/i><i><span data-contrast=\"none\">Preprint<\/span><\/i><i><span data-contrast=\"none\">, not peer-reviewed]<\/span><\/i><i><span data-contrast=\"none\">\u00a0<\/span><\/i><span data-contrast=\"auto\">Matrajt<\/span><span data-contrast=\"auto\">\u00a0et al. us<\/span><span data-contrast=\"auto\">ed<\/span><span data-contrast=\"auto\">\u00a0an age-stratified model to<\/span><span data-contrast=\"auto\">\u00a0<\/span><span data-contrast=\"auto\">determine optimal vaccine allocation\u00a0<\/span><span data-contrast=\"auto\">for a population with an age distribution based on<\/span><span data-contrast=\"auto\">\u00a0Washington State<\/span><span data-contrast=\"auto\">.<\/span><span data-contrast=\"auto\">\u00a0<\/span><span data-contrast=\"auto\">Results suggest that 70% vaccine effectiveness (VE) would be enough to substantially mitigate the ongoing pandemic if\u00a0<\/span><span data-contrast=\"auto\">at least\u00a0<\/span><span data-contrast=\"auto\">50%\u00a0<\/span><span data-contrast=\"auto\">of the<\/span><span data-contrast=\"auto\">\u00a0population is optimally vaccinated. For a low vaccination coverage among the population (&lt;20%), the optimal allocation to minimize death is to vaccinate the high-risk (older) age-groups first, but\u00a0<\/span><span data-contrast=\"auto\">the optimal allocation changes<\/span><span data-contrast=\"auto\">\u00a0in a scenario with higher coverage\u00a0<\/span><span data-contrast=\"auto\">(<\/span><span data-contrast=\"auto\">&gt;40-60%<\/span><span data-contrast=\"auto\">)\u00a0<\/span><span data-contrast=\"auto\">to prioritize<\/span><span data-contrast=\"auto\">\u00a0vaccine to the high-transmission groups (those aged 20-50 and children) first.\u00a0<\/span><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li>\n<\/ul>\n<p><i><span data-contrast=\"none\">Matrajt<\/span><\/i><i><span data-contrast=\"none\">\u00a0et al. (Aug 16, 2020). Vaccine Optimization for COVID-19 Who to Vaccinate First. Pre-print downloaded Aug 17 from\u00a0<\/span><\/i><a href=\"https:\/\/doi.org\/10.1101\/2020.08.14.20175257\"><span data-contrast=\"none\">https:\/\/doi.org\/10.1101\/2020.08.14.20175257<\/span><\/a><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559685&quot;:720,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/p>\n<\/p>\n<\/div>\n<p>\t\t\t\t\t\t\t\t\t<!-- <a href=\"\" class=\"su-post-comments-link\"><\/a> --><\/p>\n<\/div>\n<div id=\"su-post-9093\" class=\"su-post\">\n<h5 class=\"su-post-title\">Maximizing Education While Minimizing COVID Risk\u202f: Priorities and Pitfalls for Reopening Schools<\/h5>\n<p>\t\t\t\t<!-- \n\n\n\n\n\n\n\n\n\n\n\n<div class=\"su-post-meta\">\n\t\t\t\t\t: \t\t\t\t<\/div>\n\n\n\n\n\n\n\n\n\n\n\n --><\/p>\n<div class=\"su-post-excerpt\">\n<ul>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"34\" data-aria-posinset=\"2019\" data-aria-level=\"1\"><i><span data-contrast=\"none\">[<\/span><\/i><i><span data-contrast=\"none\">Preprint<\/span><\/i><i><span data-contrast=\"none\">, not peer-reviewed]<\/span><\/i><i><span data-contrast=\"none\">\u00a0<\/span><\/i><span data-contrast=\"auto\">Cohen et al.\u00a0<\/span><span data-contrast=\"auto\">estimated<\/span><span data-contrast=\"auto\">\u00a0that 5-42% of schools would have at least one person with active COVID-19 on the first day of arrival<\/span><span data-contrast=\"auto\">,\u00a0<\/span><span data-contrast=\"auto\">depending on the incidence of COVID-19 in the\u00a0<\/span><span data-contrast=\"auto\">local\u00a0<\/span><span data-contrast=\"auto\">community.\u00a0<\/span><span data-contrast=\"auto\">Using the\u00a0<\/span><span data-contrast=\"auto\">Covasim<\/span><span data-contrast=\"auto\">\u00a0agent-based model<\/span><span data-contrast=\"auto\">,\u00a0<\/span><span data-contrast=\"auto\">they estimate that\u00a0<\/span><span data-contrast=\"auto\">10-25% of staff and 6-17% of students would be infected in the first three months<\/span><span data-contrast=\"auto\">\u00a0in a scenario where\u00a0<\/span><span data-contrast=\"auto\">all students return to in-person learning<\/span><span data-contrast=\"auto\">\u00a0without mitigation measures such as\u00a0<\/span><span data-contrast=\"auto\">face masks<\/span><span data-contrast=\"auto\">, six-foot separation, and handwashing<\/span><span data-contrast=\"auto\">. An approach with only elementary schools returning to in-person on an A\/B 2-day a week schedule, while other schools remain remote, would reduce the cumulative risk in school to below 1.2%<\/span><span data-contrast=\"auto\">. They estimated more than seven times as many COVID-19 cases among people in schools if schools reopen\u00a0<\/span><span data-contrast=\"auto\">at a community incidence rate of 110\/100,000 versus 20\/10,000<\/span><span data-contrast=\"auto\">.<\/span><span data-contrast=\"auto\">\u00a0<\/span><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li>\n<\/ul>\n<p><i><span data-contrast=\"none\">Cohen et al. (Aug 13, 2020). Maximizing Education While Minimizing COVID Risk\u202f: Priorities and Pitfalls for Reopening Schools. Institute for Disease Modeling.\u00a0<\/span><\/i><a href=\"https:\/\/covid.idmod.org\/data\/Maximizing_education_while_minimizing_COVID_risk.pdf\"><span data-contrast=\"none\">https:\/\/covid.idmod.org\/data\/Maximizing_education_while_minimizing_COVID_risk.pdf<\/span><\/a><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559685&quot;:720,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/p>\n<\/p>\n<\/div>\n<p>\t\t\t\t\t\t\t\t\t<!-- <a href=\"\" class=\"su-post-comments-link\"><\/a> --><\/p>\n<\/div>\n<div id=\"su-post-9091\" class=\"su-post\">\n<h5 class=\"su-post-title\">Widespread Testing Case Isolation and Contact Tracing May Allow Safe School Reopening with Continued Moderate Physical Distancing a Modeling Analysis of King County WA Data<\/h5>\n<p>\t\t\t\t<!-- \n\n\n\n\n\n\n\n\n\n\n\n<div class=\"su-post-meta\">\n\t\t\t\t\t: \t\t\t\t<\/div>\n\n\n\n\n\n\n\n\n\n\n\n --><\/p>\n<div class=\"su-post-excerpt\">\n<ul>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"34\" data-aria-posinset=\"2019\" data-aria-level=\"1\"><i><span data-contrast=\"none\">[<\/span><\/i><i><span data-contrast=\"none\">Preprint<\/span><\/i><i><span data-contrast=\"none\">, not peer-reviewed]<\/span><\/i><i><span data-contrast=\"none\">\u00a0<\/span><\/i><span data-contrast=\"auto\">Modeling based on King County in Washington State<\/span><span data-contrast=\"auto\">\u00a0<\/span><span data-contrast=\"auto\">indicates that returning to a level of 75% of<\/span><span data-contrast=\"auto\">\u00a0<\/span><span data-contrast=\"auto\">pre-COVID<\/span><span data-contrast=\"auto\">-19<\/span><span data-contrast=\"auto\">\u00a0physical interactions<\/span><span data-contrast=\"auto\">\u00a0<\/span><span data-contrast=\"auto\">between May 15-July 15 would result in 350 daily deaths by early September 2020. Maintaining less than 45%\u00a0<\/span><span data-contrast=\"auto\">of\u00a0<\/span><span data-contrast=\"auto\">pre-COVID<\/span><span data-contrast=\"auto\">-19<\/span><span data-contrast=\"auto\">\u00a0physical interactions<\/span><span data-contrast=\"auto\">\u00a0<\/span><span data-contrast=\"auto\">was required to ensure low levels of daily infections and deaths. A combination of increased testing, isolation of symptomatic infections, and contact tracing permitted 60%\u00a0<\/span><span data-contrast=\"auto\">of\u00a0<\/span><span data-contrast=\"auto\">pre-COVID<\/span><span data-contrast=\"auto\">-19<\/span><span data-contrast=\"auto\">\u00a0physical interactions<\/span><span data-contrast=\"auto\">\u00a0<\/span><span data-contrast=\"auto\">and allowed opening of schools with &lt;15 daily deaths.\u00a0<\/span><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li>\n<\/ul>\n<p><i><span data-contrast=\"none\">Bracis<\/span><\/i><i><span data-contrast=\"none\">\u00a0et al. (Aug 16, 2020). Widespread Testing Case Isolation and Contact Tracing May Allow Safe School Reopening with Continued Moderate Physical Distancing a Modeling Analysis of King County WA Data. Pre-print downloaded Aug 17 from\u00a0<\/span><\/i><a href=\"https:\/\/doi.org\/10.1101\/2020.08.14.20174649\"><span data-contrast=\"none\">https:\/\/doi.org\/10.1101\/2020.08.14.20174649<\/span><\/a><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559685&quot;:720,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/p>\n<\/p>\n<\/div>\n<p>\t\t\t\t\t\t\t\t\t<!-- <a href=\"\" class=\"su-post-comments-link\"><\/a> --><\/p>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<h3><strong>Other Resources and Commentaries<\/strong><\/h3>\n<ul>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"32\" data-aria-posinset=\"2019\" data-aria-level=\"1\"><a href=\"https:\/\/doi.org\/10.1016\/S0140-6736(20)31749-9\"><span data-contrast=\"none\">Humanitarian Crises in a Global Pandemic<\/span><\/a><span data-contrast=\"auto\">\u00a0<\/span><span data-contrast=\"auto\">\u2013 The Lancet (Aug 15)\u00a0<\/span><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"32\" data-aria-posinset=\"2019\" data-aria-level=\"1\"><a href=\"https:\/\/doi.org\/10.1016\/S2213-2600(20)30360-X\"><span data-contrast=\"none\">The EVALI Outbreak and Vaping in the COVID-19 Era<\/span><\/a><span data-contrast=\"auto\">\u00a0\u2013 The Lancet Respiratory Medicine (Aug 14)\u00a0<\/span><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li>\n<\/ul>\n<ul>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"32\" data-aria-posinset=\"2019\" data-aria-level=\"1\"><a href=\"https:\/\/doi.org\/10.1001\/jama.2020.14661\"><span data-contrast=\"none\">Influenza in the COVID-19 Era<\/span><\/a><span data-contrast=\"auto\">\u00a0\u2013 JAMA (Aug 14)\u00a0<\/span><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"32\" data-aria-posinset=\"2019\" data-aria-level=\"1\"><a href=\"https:\/\/doi.org\/10.1001\/jamanetworkopen.2020.17703\"><span data-contrast=\"none\">Comparison of International Classification of Diseases and Related Health Problems, Tenth Revision Codes With Electronic Medical Records Among Patients With Symptoms of Coronavirus Disease 2019<\/span><\/a><span data-contrast=\"auto\">\u00a0\u2013 JAMA Network Open (Aug 14)\u00a0<\/span><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"32\" data-aria-posinset=\"2019\" data-aria-level=\"1\"><a href=\"https:\/\/doi.org\/10.1101\/2020.08.15.20102699\"><span data-contrast=\"none\">The Effect of Smoking on COVID-19 Symptom Severity Systematic Review and Meta-Analysis<\/span><\/a><span data-contrast=\"auto\">\u00a0\u2013\u00a0<\/span><span data-contrast=\"auto\">medRxiv<\/span><span data-contrast=\"auto\">\u00a0<\/span><span data-contrast=\"auto\">(Aug 17)\u00a0<\/span><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li>\n<\/ul>\n<p><span data-ccp-props=\"{&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><i><span data-contrast=\"auto\">R<\/span><\/i><i><span data-contrast=\"auto\">eport prepared by the UW MetaCenter for Pandemic Preparedness and Global Health Security\u00a0<\/span><\/i><i><span data-contrast=\"auto\">and the START Center\u00a0<\/span><\/i><i><span data-contrast=\"auto\">in collaboration with and on behalf of WA DOH COVID-19 Inciden<\/span><\/i><i><span data-contrast=\"auto\">t<\/span><\/i><i><span data-contrast=\"auto\">\u00a0Management Team<\/span><\/i><span data-ccp-props=\"{&quot;201341983&quot;:0,&quot;335551550&quot;:2,&quot;335551620&quot;:2,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Utah reported 1,389 COVID-19 cases associated with 210 workplace-related outbreaks during March 6\u2013June 5, 2020, which occurred most commonly in the areas of manufacturing (20%), construction (15%), and wholesale trade (14%). Hispanic and nonwhite workers accounted for a large disproportional number of workplace outbreak-associated COVID-19 cases.<\/p>\n<div><a class=\"more\" href=\"https:\/\/depts.washington.edu\/pandemicalliance\/2020\/08\/17\/widespread-testing-case-isolation-and-contact-tracing-may-allow-safe-school-reopening-with-continued-moderate-physical-distancing-a-modeling-analysis-of-king-county-wa-data-2\/\">Read more<\/a><\/div>\n","protected":false},"author":8,"featured_media":345,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":"","_links_to":"","_links_to_target":""},"categories":[5],"tags":[],"topic":[],"class_list":["post-9073","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-covid-19-literature-situation-report"],"_links":{"self":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/9073","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/users\/8"}],"replies":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/comments?post=9073"}],"version-history":[{"count":1,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/9073\/revisions"}],"predecessor-version":[{"id":9099,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/9073\/revisions\/9099"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/media\/345"}],"wp:attachment":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/media?parent=9073"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/categories?post=9073"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/tags?post=9073"},{"taxonomy":"topic","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/topic?post=9073"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}