{"id":9081,"date":"2020-08-17T11:50:42","date_gmt":"2020-08-17T18:50:42","guid":{"rendered":"https:\/\/depts.washington.edu\/pandemicalliance\/?p=9081"},"modified":"2021-04-13T11:51:20","modified_gmt":"2021-04-13T18:51:20","slug":"tocilizumab-among-patients-with-covid-19-in-the-intensive-care-unit-a-multicentre-observational-study","status":"publish","type":"post","link":"https:\/\/depts.washington.edu\/pandemicalliance\/2020\/08\/17\/tocilizumab-among-patients-with-covid-19-in-the-intensive-care-unit-a-multicentre-observational-study\/","title":{"rendered":"Tocilizumab among Patients with COVID-19 in the Intensive Care Unit: A\u00a0Multicentre\u00a0Observational Study"},"content":{"rendered":"<ul>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"34\" data-aria-posinset=\"2019\" data-aria-level=\"1\"><span data-contrast=\"auto\">Based on<\/span><span data-contrast=\"auto\">\u00a0210 patients with laboratory-confirmed COVID-19<\/span><span data-contrast=\"auto\">\u00a0<\/span><span data-contrast=\"auto\">in\u00a0<\/span><span data-contrast=\"auto\">ICUs in\u00a0<\/span><span data-contrast=\"auto\">New Jersey,\u00a0<\/span><span data-contrast=\"auto\">r<\/span><span data-contrast=\"auto\">eceiving\u00a0<\/span><span data-contrast=\"auto\">the drug\u00a0<\/span><span data-contrast=\"auto\">tocilizumab was associated with a\u00a0<\/span><span data-contrast=\"auto\">40% reduction in\u00a0<\/span><span data-contrast=\"auto\">mortality (<\/span><span data-contrast=\"auto\">a<\/span><span data-contrast=\"auto\">HR<\/span><span data-contrast=\"auto\">=<\/span><span data-contrast=\"auto\">0.6, 95%CI 0.5-0.9)<\/span><span data-contrast=\"auto\">\u00a0<\/span><span data-contrast=\"auto\">compared\u00a0<\/span><span data-contrast=\"auto\">with\u00a0<\/span><span data-contrast=\"auto\">420 propensity score-matched patients who did not receive tocilizumab.<\/span><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li>\n<\/ul>\n<p><i><span data-contrast=\"none\">Biran<\/span><\/i><i><span data-contrast=\"none\">\u00a0et al. (Aug 14, 2020). Tocilizumab among Patients with COVID-19 in the Intensive Care Unit: A\u00a0<\/span><\/i><i><span data-contrast=\"none\">Multicentre<\/span><\/i><i><span data-contrast=\"none\">\u00a0Observational Study. The Lancet Rheumatology.\u00a0<\/span><\/i><a href=\"https:\/\/doi.org\/10.1016\/S2665-9913(20)30277-0\"><span data-contrast=\"none\">https:\/\/doi.org\/10.1016\/S2665-9913(20)30277-0<\/span><\/a><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559685&quot;:720,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Based on\u00a0210 patients with laboratory-confirmed COVID-19\u00a0in\u00a0ICUs in\u00a0New Jersey,\u00a0receiving\u00a0the drug\u00a0tocilizumab was associated with a\u00a040% reduction in\u00a0mortality (aHR=0.6, 95%CI 0.5-0.9)\u00a0compared\u00a0with\u00a0420 propensity score-matched patients who did not receive tocilizumab.\u00a0 Biran\u00a0et al. (Aug 14, 2020). Tocilizumab among Patients with COVID-19 in the Intensive Care Unit: A\u00a0Multicentre\u00a0Observational Study. The Lancet Rheumatology.\u00a0https:\/\/doi.org\/10.1016\/S2665-9913(20)30277-0\u00a0<\/p>\n<div><a class=\"more\" href=\"https:\/\/depts.washington.edu\/pandemicalliance\/2020\/08\/17\/tocilizumab-among-patients-with-covid-19-in-the-intensive-care-unit-a-multicentre-observational-study\/\">Read more<\/a><\/div>\n","protected":false},"author":8,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":"","_links_to":"","_links_to_target":""},"categories":[6],"tags":[],"topic":[19],"class_list":["post-9081","post","type-post","status-publish","format-standard","hentry","category-article-summary","topic-testing-and-treatment"],"_links":{"self":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/9081","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/users\/8"}],"replies":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/comments?post=9081"}],"version-history":[{"count":1,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/9081\/revisions"}],"predecessor-version":[{"id":9082,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/9081\/revisions\/9082"}],"wp:attachment":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/media?parent=9081"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/categories?post=9081"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/tags?post=9081"},{"taxonomy":"topic","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/topic?post=9081"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}