{"id":9083,"date":"2020-08-17T11:51:29","date_gmt":"2020-08-17T18:51:29","guid":{"rendered":"https:\/\/depts.washington.edu\/pandemicalliance\/?p=9083"},"modified":"2021-04-13T11:52:09","modified_gmt":"2021-04-13T18:52:09","slug":"pre-covid-19-humoral-immunity-to-common-coronaviruses-does-not-confer-cross-protection-against-sars-cov-2","status":"publish","type":"post","link":"https:\/\/depts.washington.edu\/pandemicalliance\/2020\/08\/17\/pre-covid-19-humoral-immunity-to-common-coronaviruses-does-not-confer-cross-protection-against-sars-cov-2\/","title":{"rendered":"Pre-COVID-19 Humoral Immunity to Common Coronaviruses Does Not Confer Cross-Protection against SARS-CoV-2"},"content":{"rendered":"<ul>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"45\" data-aria-posinset=\"1\" data-aria-level=\"1\"><i><span data-contrast=\"none\">[Preprint, not peer-reviewed]\u00a0<\/span><\/i><span data-contrast=\"auto\">Miyara<\/span><span data-contrast=\"auto\">\u00a0et al. analyzed the sera of 76 healthy French donors drawn in 2015 to test the hypothesis that past infections or immunizations related to the common alpha- and beta-coronavirus could lead to cross-protecti<\/span><span data-contrast=\"auto\">on against SARS-CoV-2. They reported 6 serological samples (<\/span><span data-contrast=\"auto\">8<\/span><span data-contrast=\"auto\">%) were reactive to SARS-CoV-2 antigens.\u00a0<\/span><span data-contrast=\"auto\">Additionally<\/span><span data-contrast=\"auto\">, they detected serum IgG reactivity to common coronaviruses in the early sera of 8 patients with severe COVID-19 before the appearance of anti-SARS-CoV-2 antibodies. The authors<\/span><span data-contrast=\"auto\">\u00a0concluded that pre-existing immunity to common coronaviruses does not confer cross-protection against SARS-CoV-2.<\/span><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559685&quot;:360,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li>\n<\/ul>\n<p><i><span data-contrast=\"none\">Miyara<\/span><\/i><i><span data-contrast=\"none\">\u00a0et al. (Aug 15, 2020). Pre-COVID-19 Humoral Immunity to Common Coronaviruses Does Not Confer Cross-Protection against SARS-CoV-2. Pre-print downloaded Aug 17 from\u00a0<\/span><\/i><a href=\"https:\/\/doi.org\/10.1101\/2020.08.14.20173393\"><span data-contrast=\"none\">https:\/\/doi.org\/10.1101\/2020.08.14.20173393<\/span><\/a><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559685&quot;:720,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"<p>[Preprint, not peer-reviewed]\u00a0Miyara\u00a0et al. analyzed the sera of 76 healthy French donors drawn in 2015 to test the hypothesis that past infections or immunizations related to the common alpha- and beta-coronavirus could lead to cross-protection against SARS-CoV-2. They reported 6 serological samples (8%) were reactive to SARS-CoV-2 antigens.\u00a0Additionally, they detected serum IgG reactivity to common&#8230;<\/p>\n<div><a class=\"more\" href=\"https:\/\/depts.washington.edu\/pandemicalliance\/2020\/08\/17\/pre-covid-19-humoral-immunity-to-common-coronaviruses-does-not-confer-cross-protection-against-sars-cov-2\/\">Read more<\/a><\/div>\n","protected":false},"author":8,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":"","_links_to":"","_links_to_target":""},"categories":[6],"tags":[],"topic":[31],"class_list":["post-9083","post","type-post","status-publish","format-standard","hentry","category-article-summary","topic-vaccines-and-immunity"],"_links":{"self":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/9083","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/users\/8"}],"replies":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/comments?post=9083"}],"version-history":[{"count":1,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/9083\/revisions"}],"predecessor-version":[{"id":9084,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/9083\/revisions\/9084"}],"wp:attachment":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/media?parent=9083"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/categories?post=9083"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/tags?post=9083"},{"taxonomy":"topic","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/topic?post=9083"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}