{"id":9163,"date":"2020-08-18T11:01:27","date_gmt":"2020-08-18T18:01:27","guid":{"rendered":"https:\/\/depts.washington.edu\/pandemicalliance\/?p=9163"},"modified":"2021-04-15T11:02:18","modified_gmt":"2021-04-15T18:02:18","slug":"sars-cov-2-antibody-responses-correlate-with-resolution-of-rnaemia-but-are-short-lived-in-patients-with-mild-illness","status":"publish","type":"post","link":"https:\/\/depts.washington.edu\/pandemicalliance\/2020\/08\/18\/sars-cov-2-antibody-responses-correlate-with-resolution-of-rnaemia-but-are-short-lived-in-patients-with-mild-illness\/","title":{"rendered":"SARS-CoV-2 Antibody Responses Correlate with Resolution of\u00a0RNAemia\u00a0But Are Short-Lived in Patients with Mild Illness"},"content":{"rendered":"<ul>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"34\" data-aria-posinset=\"2019\" data-aria-level=\"1\"><i><span data-contrast=\"none\">[Pre-print, not peer reviewed]<\/span><\/i><i><span data-contrast=\"none\">\u00a0<\/span><\/i><span data-contrast=\"auto\">S<\/span><span data-contrast=\"auto\">everely ill patients developed significantly higher SARS-CoV-2 specific antibody responses<\/span><span data-contrast=\"auto\">, based on analysis of\u00a0<\/span><span data-contrast=\"auto\">625 serial plasma samples from 40 hospitalized patients\u00a0<\/span><span data-contrast=\"auto\">with COVID-19\u00a0<\/span><span data-contrast=\"auto\">and 170 SARS-CoV-2 infected outpatients and asymptomatic individuals<\/span><span data-contrast=\"auto\">.<\/span><span data-contrast=\"auto\">\u00a0<\/span><span data-contrast=\"auto\">The development of\u00a0<\/span><span data-contrast=\"auto\">plasma antibodies was<\/span><span data-contrast=\"auto\">\u00a0<\/span><span data-contrast=\"auto\">also correlated with decreases in viral\u00a0RNAemia<\/span><span data-contrast=\"auto\">, suggesting\u00a0<\/span><span data-contrast=\"auto\">potential humoral immune clearance of virus<\/span><span data-contrast=\"auto\">. Additionally, the serological responses of outpatient and asymptomatic individuals were found to decrease within 2 months.<\/span><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li>\n<\/ul>\n<p><i><span data-contrast=\"none\">R<\/span><\/i><i><span data-contrast=\"none\">\u00f6<\/span><\/i><i><span data-contrast=\"none\">ltgen\u00a0et al. (Aug 17, 2020). SARS-CoV-2 Antibody Responses Correlate with Resolution of\u00a0RNAemia\u00a0But Are Short-Lived in Patients with Mild Illness.\u00a0<\/span><\/i><i><span data-contrast=\"none\">Pre-print downloaded Aug 18 from<\/span><\/i><i><span data-contrast=\"none\">\u00a0<\/span><\/i><a href=\"https:\/\/doi.org\/10.1101\/2020.08.15.20175794\"><span data-contrast=\"none\">https:\/\/doi.org\/10.1101\/2020.08.15.20175794<\/span><\/a><i><span data-contrast=\"none\">\u00a0<\/span><\/i><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559685&quot;:720,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"<p>[Pre-print, not peer reviewed]\u00a0Severely ill patients developed significantly higher SARS-CoV-2 specific antibody responses, based on analysis of\u00a0625 serial plasma samples from 40 hospitalized patients\u00a0with COVID-19\u00a0and 170 SARS-CoV-2 infected outpatients and asymptomatic individuals.\u00a0The development of\u00a0plasma antibodies was\u00a0also correlated with decreases in viral\u00a0RNAemia, suggesting\u00a0potential humoral immune clearance of virus. Additionally, the serological responses of outpatient and asymptomatic&#8230;<\/p>\n<div><a class=\"more\" href=\"https:\/\/depts.washington.edu\/pandemicalliance\/2020\/08\/18\/sars-cov-2-antibody-responses-correlate-with-resolution-of-rnaemia-but-are-short-lived-in-patients-with-mild-illness\/\">Read more<\/a><\/div>\n","protected":false},"author":8,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":"","_links_to":"","_links_to_target":""},"categories":[6],"tags":[],"topic":[19],"class_list":["post-9163","post","type-post","status-publish","format-standard","hentry","category-article-summary","topic-testing-and-treatment"],"_links":{"self":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/9163","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/users\/8"}],"replies":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/comments?post=9163"}],"version-history":[{"count":1,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/9163\/revisions"}],"predecessor-version":[{"id":9164,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/9163\/revisions\/9164"}],"wp:attachment":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/media?parent=9163"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/categories?post=9163"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/tags?post=9163"},{"taxonomy":"topic","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/topic?post=9163"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}