{"id":9302,"date":"2021-04-20T13:08:26","date_gmt":"2021-04-20T20:08:26","guid":{"rendered":"https:\/\/depts.washington.edu\/pandemicalliance\/?p=9302"},"modified":"2021-04-22T13:09:12","modified_gmt":"2021-04-22T20:09:12","slug":"severe-acute-respiratory-syndrome-coronavirus-2-convalescent-plasma-versus-standard-plasma-in-coronavirus-disease-2019-infected-hospitalized-patients-in-new-york","status":"publish","type":"post","link":"https:\/\/depts.washington.edu\/pandemicalliance\/2021\/04\/20\/severe-acute-respiratory-syndrome-coronavirus-2-convalescent-plasma-versus-standard-plasma-in-coronavirus-disease-2019-infected-hospitalized-patients-in-new-york\/","title":{"rendered":"Severe Acute Respiratory Syndrome Coronavirus 2 Convalescent Plasma Versus Standard Plasma in Coronavirus Disease 2019 Infected Hospitalized Patients in New York"},"content":{"rendered":"<ul>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">No difference in ventilator-free days through 28 days (p=0.86) was observed between patients randomized to receive convalescent plasma (CP) vs standard plasma in a 4:1 randomized doubled-blind placebo-controlled trial (n=74). CP increased antibody levels by 14%, whereas standard plasma led to a 7% decrease. All-cause mortality through 90 days was non-significantly lower in the CP group (27% vs 33%, p=0.63). The trial was halted after the FDA granted emergency use authorization for CP.<\/span><\/li>\n<\/ul>\n<p><i><span style=\"font-weight: 400\">Bennett-Guerrero et al.\u00a0(Apr 16, 2021). Severe Acute Respiratory Syndrome Coronavirus 2 Convalescent Plasma Versus Standard Plasma in Coronavirus Disease 2019 Infected Hospitalized Patients in New York. Critical Care Medicine. <\/span><\/i><a href=\"https:\/\/doi.org\/10.1097\/CCM.0000000000005066\"><span style=\"font-weight: 400\">https:\/\/doi.org\/10.1097\/CCM.0000000000005066<\/span><\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>No difference in ventilator-free days through 28 days (p=0.86) was observed between patients randomized to receive convalescent plasma (CP) vs standard plasma in a 4:1 randomized doubled-blind placebo-controlled trial (n=74). CP increased antibody levels by 14%, whereas standard plasma led to a 7% decrease. All-cause mortality through 90 days was non-significantly lower in the CP&#8230;<\/p>\n<div><a class=\"more\" href=\"https:\/\/depts.washington.edu\/pandemicalliance\/2021\/04\/20\/severe-acute-respiratory-syndrome-coronavirus-2-convalescent-plasma-versus-standard-plasma-in-coronavirus-disease-2019-infected-hospitalized-patients-in-new-york\/\">Read more<\/a><\/div>\n","protected":false},"author":8,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":"","_links_to":"","_links_to_target":""},"categories":[6],"tags":[28],"topic":[19],"class_list":["post-9302","post","type-post","status-publish","format-standard","hentry","category-article-summary","tag-treatment","topic-testing-and-treatment"],"_links":{"self":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/9302","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/users\/8"}],"replies":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/comments?post=9302"}],"version-history":[{"count":1,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/9302\/revisions"}],"predecessor-version":[{"id":9303,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/9302\/revisions\/9303"}],"wp:attachment":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/media?parent=9302"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/categories?post=9302"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/tags?post=9302"},{"taxonomy":"topic","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/topic?post=9302"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}