{"id":9308,"date":"2021-04-20T13:10:54","date_gmt":"2021-04-20T20:10:54","guid":{"rendered":"https:\/\/depts.washington.edu\/pandemicalliance\/?p=9308"},"modified":"2021-04-22T13:11:49","modified_gmt":"2021-04-22T20:11:49","slug":"serological-investigation-of-asymptomatic-cases-of-sars-cov-2-infection-reveals-weak-and-declining-antibody-responses","status":"publish","type":"post","link":"https:\/\/depts.washington.edu\/pandemicalliance\/2021\/04\/20\/serological-investigation-of-asymptomatic-cases-of-sars-cov-2-infection-reveals-weak-and-declining-antibody-responses\/","title":{"rendered":"Serological Investigation of Asymptomatic Cases of SARS-CoV-2 Infection Reveals Weak and Declining Antibody Responses"},"content":{"rendered":"<ul>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">SARS-CoV-2 anti-nucleocapsid IgM antibodies were detected in a small proportion (6%) of asymptomatic food workers (n=508) in Wuhan in April 2020. In a follow-up survey among 21 of seropositive participants, IgM levels had declined by up to 50% in 90% of individuals. In comparison to a cohort of symptomatic patients 2 months after infection, asymptomatic individuals had lower IgM and IgG-RBD and memory B cell levels at a similar time point after infection.<\/span><\/li>\n<\/ul>\n<p><i><span style=\"font-weight: 400\">Yang et al.\u00a0(Apr 19, 2021). Serological Investigation of Asymptomatic Cases of SARS-CoV-2 Infection Reveals Weak and Declining Antibody Responses. Emerging Microbes &amp; Infections. <\/span><\/i><a href=\"https:\/\/doi.org\/10.1080\/22221751.2021.1919032\"><span style=\"font-weight: 400\">https:\/\/doi.org\/10.1080\/22221751.2021.1919032<\/span><\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>SARS-CoV-2 anti-nucleocapsid IgM antibodies were detected in a small proportion (6%) of asymptomatic food workers (n=508) in Wuhan in April 2020. In a follow-up survey among 21 of seropositive participants, IgM levels had declined by up to 50% in 90% of individuals. In comparison to a cohort of symptomatic patients 2 months after infection, asymptomatic&#8230;<\/p>\n<div><a class=\"more\" href=\"https:\/\/depts.washington.edu\/pandemicalliance\/2021\/04\/20\/serological-investigation-of-asymptomatic-cases-of-sars-cov-2-infection-reveals-weak-and-declining-antibody-responses\/\">Read more<\/a><\/div>\n","protected":false},"author":8,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":"","_links_to":"","_links_to_target":""},"categories":[6],"tags":[67,107,32],"topic":[31],"class_list":["post-9308","post","type-post","status-publish","format-standard","hentry","category-article-summary","tag-antibodies","tag-asymptomatic-infection","tag-immunity","topic-vaccines-and-immunity"],"_links":{"self":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/9308","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/users\/8"}],"replies":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/comments?post=9308"}],"version-history":[{"count":1,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/9308\/revisions"}],"predecessor-version":[{"id":9309,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/9308\/revisions\/9309"}],"wp:attachment":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/media?parent=9308"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/categories?post=9308"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/tags?post=9308"},{"taxonomy":"topic","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/topic?post=9308"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}