{"id":9316,"date":"2021-04-20T13:15:06","date_gmt":"2021-04-20T20:15:06","guid":{"rendered":"https:\/\/depts.washington.edu\/pandemicalliance\/?p=9316"},"modified":"2021-04-22T13:15:56","modified_gmt":"2021-04-22T20:15:56","slug":"the-increase-in-the-risk-of-severity-and-fatality-rate-of-covid-19-in-southern-brazil-after-the-emergence-of-the-variant-of-concern-voc-sars-cov-2-p-1-was-greater-among-young-adults-without-pre-exis","status":"publish","type":"post","link":"https:\/\/depts.washington.edu\/pandemicalliance\/2021\/04\/20\/the-increase-in-the-risk-of-severity-and-fatality-rate-of-covid-19-in-southern-brazil-after-the-emergence-of-the-variant-of-concern-voc-sars-cov-2-p-1-was-greater-among-young-adults-without-pre-exis\/","title":{"rendered":"The Increase in the Risk of Severity and Fatality Rate of Covid-19 in Southern Brazil after the Emergence of the Variant of Concern (VOC) SARS-CoV-2 P.1 Was Greater among Young Adults without Pre-Existing Risk Conditions"},"content":{"rendered":"<ul>\n<li style=\"font-weight: 400\"><i><span style=\"font-weight: 400\">[Pre-print, not peer-reviewed]<\/span><\/i><span style=\"font-weight: 400\"> A higher proportion of younger patients (age &lt;60 years) were observed among severe COVID-19 cases leading to death (28%) in the second wave in Brazil (February 2021) as compared to the first wave (18%) (November-December 2020). This second wave was predominantly the P.1 variant. Similarly, a higher proportion of patients without pre-existing conditions was present among severe COVID-19 cases (22% vs 13%). While the case fatality rate (CFR) increased for all age groups between the first and second wave, females aged 20-39 years with no pre-existing conditions had a 5.6-fold higher CFR during the second vs first wave and individuals aged 40-59 years had a 7.7-fold higher CFR.<\/span><\/li>\n<\/ul>\n<p><i><span style=\"font-weight: 400\">Freitas et al.\u00a0(Apr 19, 2021). The Increase in the Risk of Severity and Fatality Rate of Covid-19 in Southern Brazil after the Emergence of the Variant of Concern (VOC) SARS-CoV-2 P.1 Was Greater among Young Adults without Pre-Existing Risk Conditions. Pre-print downloaded Apr 20 from <\/span><\/i><a href=\"https:\/\/doi.org\/10.1101\/2021.04.13.21255281\"><span style=\"font-weight: 400\">https:\/\/doi.org\/10.1101\/2021.04.13.21255281<\/span><\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>[Pre-print, not peer-reviewed] A higher proportion of younger patients (age &lt;60 years) were observed among severe COVID-19 cases leading to death (28%) in the second wave in Brazil (February 2021) as compared to the first wave (18%) (November-December 2020). This second wave was predominantly the P.1 variant. Similarly, a higher proportion of patients without pre-existing&#8230;<\/p>\n<div><a class=\"more\" href=\"https:\/\/depts.washington.edu\/pandemicalliance\/2021\/04\/20\/the-increase-in-the-risk-of-severity-and-fatality-rate-of-covid-19-in-southern-brazil-after-the-emergence-of-the-variant-of-concern-voc-sars-cov-2-p-1-was-greater-among-young-adults-without-pre-exis\/\">Read more<\/a><\/div>\n","protected":false},"author":8,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":"","_links_to":"","_links_to_target":""},"categories":[6],"tags":[29,159],"topic":[16],"class_list":["post-9316","post","type-post","status-publish","format-standard","hentry","category-article-summary","tag-public-health","tag-variants","topic-public-health-policy-and-practice"],"_links":{"self":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/9316","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/users\/8"}],"replies":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/comments?post=9316"}],"version-history":[{"count":1,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/9316\/revisions"}],"predecessor-version":[{"id":9317,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/9316\/revisions\/9317"}],"wp:attachment":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/media?parent=9316"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/categories?post=9316"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/tags?post=9316"},{"taxonomy":"topic","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/topic?post=9316"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}