{"id":9406,"date":"2021-04-26T09:53:19","date_gmt":"2021-04-26T16:53:19","guid":{"rendered":"https:\/\/depts.washington.edu\/pandemicalliance\/?p=9406"},"modified":"2021-04-28T09:54:01","modified_gmt":"2021-04-28T16:54:01","slug":"asymptomatic-and-symptomatic-sars-cov-2-infections-elicit-polyfunctional-antibodies","status":"publish","type":"post","link":"https:\/\/depts.washington.edu\/pandemicalliance\/2021\/04\/26\/asymptomatic-and-symptomatic-sars-cov-2-infections-elicit-polyfunctional-antibodies\/","title":{"rendered":"Asymptomatic and Symptomatic SARS-CoV-2 Infections Elicit Polyfunctional Antibodies"},"content":{"rendered":"<ul>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">Cellular assays evaluating antibody-dependent cellular cytotoxicity (ADCC) combined with assessments of antibody titers and neutralization activity indicated that asymptomatic infection with SARS-CoV-2 induces a polyfunctional antibody response. In this study, antibody responses were slightly lower among asymptomatic than symptomatic individuals, but did not differ in neutralization activity or the ability to trigger ADCC and complement deposition.<\/span><\/li>\n<\/ul>\n<p><i><span style=\"font-weight: 400\">Dufloo et al.\u00a0(Apr 2021). Asymptomatic and Symptomatic SARS-CoV-2 Infections Elicit Polyfunctional Antibodies. Cell Reports. Medicine.<\/span><\/i> <a href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S2666379121001038\"><span style=\"font-weight: 400\">https:\/\/www.sciencedirect.com\/science\/article\/pii\/S2666379121001038h<\/span><\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Cellular assays evaluating antibody-dependent cellular cytotoxicity (ADCC) combined with assessments of antibody titers and neutralization activity indicated that asymptomatic infection with SARS-CoV-2 induces a polyfunctional antibody response. In this study, antibody responses were slightly lower among asymptomatic than symptomatic individuals, but did not differ in neutralization activity or the ability to trigger ADCC and complement&#8230;<\/p>\n<div><a class=\"more\" href=\"https:\/\/depts.washington.edu\/pandemicalliance\/2021\/04\/26\/asymptomatic-and-symptomatic-sars-cov-2-infections-elicit-polyfunctional-antibodies\/\">Read more<\/a><\/div>\n","protected":false},"author":8,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":"","_links_to":"","_links_to_target":""},"categories":[6],"tags":[32],"topic":[31],"class_list":["post-9406","post","type-post","status-publish","format-standard","hentry","category-article-summary","tag-immunity","topic-vaccines-and-immunity"],"_links":{"self":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/9406","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/users\/8"}],"replies":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/comments?post=9406"}],"version-history":[{"count":1,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/9406\/revisions"}],"predecessor-version":[{"id":9407,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/9406\/revisions\/9407"}],"wp:attachment":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/media?parent=9406"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/categories?post=9406"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/tags?post=9406"},{"taxonomy":"topic","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/topic?post=9406"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}