{"id":9412,"date":"2021-04-26T09:55:45","date_gmt":"2021-04-26T16:55:45","guid":{"rendered":"https:\/\/depts.washington.edu\/pandemicalliance\/?p=9412"},"modified":"2021-04-28T09:56:33","modified_gmt":"2021-04-28T16:56:33","slug":"first-dose-of-bnt162b2-mrna-vaccine-in-a-health-care-worker-cohort-is-associated-with-reduced-symptomatic-and-asymptomatic-sars-cov-2-infection","status":"publish","type":"post","link":"https:\/\/depts.washington.edu\/pandemicalliance\/2021\/04\/26\/first-dose-of-bnt162b2-mrna-vaccine-in-a-health-care-worker-cohort-is-associated-with-reduced-symptomatic-and-asymptomatic-sars-cov-2-infection\/","title":{"rendered":"First Dose of BNT162b2 MRNA Vaccine in a Health Care Worker Cohort Is Associated with Reduced Symptomatic and Asymptomatic SARS-CoV-2 Infection"},"content":{"rendered":"<ul>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">Among healthcare workers at a hospital in the UK, increased coverage (8.3% to 82.5%) of at least one dose of the Pfizer-BioNTech vaccination was associated with significant reductions in symptomatic and asymptomatic cases of SARS-CoV-2. There was a significant negative correlation between cumulative vaccination and PCR positive cases (R = -0.91), along with a marked negative correlation between symptomatic PCR testing rates and vaccine coverage (R = -0.90). The number of staff self-isolating due to SARS-CoV-2 dropped from 325 on January 11<\/span><span style=\"font-weight: 400\">th<\/span><span style=\"font-weight: 400\"> to 91 by February 23<\/span><span style=\"font-weight: 400\">rd<\/span><span style=\"font-weight: 400\"> (72% decrease). The proportion of positive tests from asymptomatic screening was maintained over the study period.\u00a0<\/span><\/li>\n<\/ul>\n<p><i><span style=\"font-weight: 400\">Lillie et al.\u00a0(Apr 24, 2021). First Dose of BNT162b2 MRNA Vaccine in a Health Care Worker Cohort Is Associated with Reduced Symptomatic and Asymptomatic SARS-CoV-2 Infection. Clinical Infectious Diseases. <\/span><\/i><a href=\"https:\/\/doi.org\/10.1093\/cid\/ciab351\"><span style=\"font-weight: 400\">https:\/\/doi.org\/10.1093\/cid\/ciab351<\/span><\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Among healthcare workers at a hospital in the UK, increased coverage (8.3% to 82.5%) of at least one dose of the Pfizer-BioNTech vaccination was associated with significant reductions in symptomatic and asymptomatic cases of SARS-CoV-2. There was a significant negative correlation between cumulative vaccination and PCR positive cases (R = -0.91), along with a marked&#8230;<\/p>\n<div><a class=\"more\" href=\"https:\/\/depts.washington.edu\/pandemicalliance\/2021\/04\/26\/first-dose-of-bnt162b2-mrna-vaccine-in-a-health-care-worker-cohort-is-associated-with-reduced-symptomatic-and-asymptomatic-sars-cov-2-infection\/\">Read more<\/a><\/div>\n","protected":false},"author":8,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":"","_links_to":"","_links_to_target":""},"categories":[6],"tags":[147],"topic":[31],"class_list":["post-9412","post","type-post","status-publish","format-standard","hentry","category-article-summary","tag-vaccination","topic-vaccines-and-immunity"],"_links":{"self":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/9412","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/users\/8"}],"replies":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/comments?post=9412"}],"version-history":[{"count":1,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/9412\/revisions"}],"predecessor-version":[{"id":9413,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/9412\/revisions\/9413"}],"wp:attachment":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/media?parent=9412"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/categories?post=9412"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/tags?post=9412"},{"taxonomy":"topic","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/topic?post=9412"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}