{"id":9467,"date":"2021-04-28T13:27:46","date_gmt":"2021-04-28T20:27:46","guid":{"rendered":"https:\/\/depts.washington.edu\/pandemicalliance\/?p=9467"},"modified":"2021-04-29T13:28:34","modified_gmt":"2021-04-29T20:28:34","slug":"vaccine-side-effects-and-sars-cov-2-infection-after-vaccination-in-users-of-the-covid-symptom-study-app-in-the-uk-a-prospective-observational-study","status":"publish","type":"post","link":"https:\/\/depts.washington.edu\/pandemicalliance\/2021\/04\/28\/vaccine-side-effects-and-sars-cov-2-infection-after-vaccination-in-users-of-the-covid-symptom-study-app-in-the-uk-a-prospective-observational-study\/","title":{"rendered":"Vaccine Side-Effects and SARS-CoV-2 Infection after Vaccination in Users of the COVID Symptom Study App in the UK: A Prospective Observational Study"},"content":{"rendered":"<ul>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">SARS-CoV-2 infection rates were lower in vaccinated persons, according to reports from the COVID Symptom Study app in the UK (n=627,383). Among Pfizer-BioNTech vaccine recipients, infections were lower by 58% 12-20 days and by 72% 45-59 days after the first dose compared to frequencies in unvaccinated users, and infection rates were also lower among Oxford-AstraZeneca vaccine recipients by 39% 12-20 days and 60% 21-44 days after the first dose. Individuals with prior SARS-CoV-2 infection reported experiencing systemic side-effects 1.6 times and 2.9 times more after the first dose of the Oxford-AstraZeneca and Pfizer-BioNTech vaccines, respectively, than those without prior infection. Similarly, local side-effects were higher among individuals with prior infection. Systemic and local side-effects occurred at lower frequencies than reported in phase 3 trials.\u00a0<\/span><\/li>\n<\/ul>\n<p><i><span style=\"font-weight: 400\">Menni et al.\u00a0(Apr 27, 2021). Vaccine Side-Effects and SARS-CoV-2 Infection after Vaccination in Users of the COVID Symptom Study App in the UK: A Prospective Observational Study. The Lancet Infectious Diseases. <\/span><\/i><a href=\"https:\/\/doi.org\/10.1016\/S1473-3099(21)00224-3\"><span style=\"font-weight: 400\">https:\/\/doi.org\/10.1016\/S1473-3099(21)00224-3<\/span><\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>SARS-CoV-2 infection rates were lower in vaccinated persons, according to reports from the COVID Symptom Study app in the UK (n=627,383). Among Pfizer-BioNTech vaccine recipients, infections were lower by 58% 12-20 days and by 72% 45-59 days after the first dose compared to frequencies in unvaccinated users, and infection rates were also lower among Oxford-AstraZeneca&#8230;<\/p>\n<div><a class=\"more\" href=\"https:\/\/depts.washington.edu\/pandemicalliance\/2021\/04\/28\/vaccine-side-effects-and-sars-cov-2-infection-after-vaccination-in-users-of-the-covid-symptom-study-app-in-the-uk-a-prospective-observational-study\/\">Read more<\/a><\/div>\n","protected":false},"author":8,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":"","_links_to":"","_links_to_target":""},"categories":[6],"tags":[147],"topic":[31],"class_list":["post-9467","post","type-post","status-publish","format-standard","hentry","category-article-summary","tag-vaccination","topic-vaccines-and-immunity"],"_links":{"self":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/9467","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/users\/8"}],"replies":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/comments?post=9467"}],"version-history":[{"count":1,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/9467\/revisions"}],"predecessor-version":[{"id":9468,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/9467\/revisions\/9468"}],"wp:attachment":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/media?parent=9467"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/categories?post=9467"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/tags?post=9467"},{"taxonomy":"topic","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/topic?post=9467"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}