{"id":9505,"date":"2021-04-29T17:04:56","date_gmt":"2021-04-30T00:04:56","guid":{"rendered":"https:\/\/depts.washington.edu\/pandemicalliance\/?p=9505"},"modified":"2021-04-30T17:05:39","modified_gmt":"2021-05-01T00:05:39","slug":"prothrombotic-immune-thrombocytopenia-after-covid-19-vaccine","status":"publish","type":"post","link":"https:\/\/depts.washington.edu\/pandemicalliance\/2021\/04\/29\/prothrombotic-immune-thrombocytopenia-after-covid-19-vaccine\/","title":{"rendered":"Prothrombotic Immune Thrombocytopenia after COVID-19 Vaccine"},"content":{"rendered":"<ul>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">5 cases of prothrombotic immune thrombocytopenia were identified in Germany at 5 to 11 days after receiving the first dose of the Oxford-AstraZeneca vaccine. Clinical manifestations included cerebral venous sinus thrombosis, splanchnic vein thrombosis, arterial cerebral thromboembolism, and thrombotic microangiopathy. Anti-PF4\/polyanion antibodies were detected in all patients. After anticoagulation alone or in combination with eculizumab or intravenous immunoglobulin, thromboembolic events resolved in three patients but persisted in two patients.<\/span><\/li>\n<\/ul>\n<p><i><span style=\"font-weight: 400\">Tiede et al.\u00a0(Apr 28, 2021). Prothrombotic Immune Thrombocytopenia after COVID-19 Vaccine. Blood. <\/span><\/i><a href=\"https:\/\/doi.org\/10.1182\/blood.2021011958\"><span style=\"font-weight: 400\">https:\/\/doi.org\/10.1182\/blood.2021011958<\/span><\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>5 cases of prothrombotic immune thrombocytopenia were identified in Germany at 5 to 11 days after receiving the first dose of the Oxford-AstraZeneca vaccine. Clinical manifestations included cerebral venous sinus thrombosis, splanchnic vein thrombosis, arterial cerebral thromboembolism, and thrombotic microangiopathy. Anti-PF4\/polyanion antibodies were detected in all patients. After anticoagulation alone or in combination with eculizumab&#8230;<\/p>\n<div><a class=\"more\" href=\"https:\/\/depts.washington.edu\/pandemicalliance\/2021\/04\/29\/prothrombotic-immune-thrombocytopenia-after-covid-19-vaccine\/\">Read more<\/a><\/div>\n","protected":false},"author":8,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":"","_links_to":"","_links_to_target":""},"categories":[6],"tags":[195,33],"topic":[31],"class_list":["post-9505","post","type-post","status-publish","format-standard","hentry","category-article-summary","tag-adverse-effects","tag-vaccines","topic-vaccines-and-immunity"],"_links":{"self":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/9505","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/users\/8"}],"replies":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/comments?post=9505"}],"version-history":[{"count":1,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/9505\/revisions"}],"predecessor-version":[{"id":9506,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/9505\/revisions\/9506"}],"wp:attachment":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/media?parent=9505"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/categories?post=9505"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/tags?post=9505"},{"taxonomy":"topic","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/topic?post=9505"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}