{"id":9534,"date":"2021-04-30T09:55:07","date_gmt":"2021-04-30T16:55:07","guid":{"rendered":"https:\/\/depts.washington.edu\/pandemicalliance\/?p=9534"},"modified":"2021-05-04T09:55:50","modified_gmt":"2021-05-04T16:55:50","slug":"sars-cov-2-seroprevalence-and-igg-concentration-and-pseudovirus-neutralising-antibody-titres-after-infection-compared-by-hiv-status-a-matched-case-control-observational-study","status":"publish","type":"post","link":"https:\/\/depts.washington.edu\/pandemicalliance\/2021\/04\/30\/sars-cov-2-seroprevalence-and-igg-concentration-and-pseudovirus-neutralising-antibody-titres-after-infection-compared-by-hiv-status-a-matched-case-control-observational-study\/","title":{"rendered":"SARS-CoV-2 Seroprevalence, and IgG Concentration and Pseudovirus Neutralising Antibody Titres after Infection, Compared by HIV Status: A Matched Case-Control Observational Study"},"content":{"rendered":"<ul>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">Persons living with HIV had lower SARS-CoV-2 IgG seroprevalence (3.7%) compared to persons without HIV (7.4%), according to a retrospective matched case-control study (N=2,200) of remnant serum samples from US adults presenting for routine laboratory testing. However, among those who had past SARS-CoV-2 infection, persons living with HIV were more likely to have had severe COVID-19 (OR = 5.5) and have lower IgG concentrations and pseudovirus neutralizing antibody titers, indicating a diminished immunological response.\u00a0<\/span><\/li>\n<\/ul>\n<p><i><span style=\"font-weight: 400\">Spinelli et al. (Apr 30, 2021). SARS-CoV-2 Seroprevalence, and IgG Concentration and Pseudovirus Neutralising Antibody Titres after Infection, Compared by HIV Status: A Matched Case-Control Observational Study. The Lancet HIV. <\/span><\/i><a href=\"https:\/\/doi.org\/10.1016\/S2352-3018(21)00072-2\"><span style=\"font-weight: 400\">https:\/\/doi.org\/10.1016\/S2352-3018(21)00072-2<\/span><\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Persons living with HIV had lower SARS-CoV-2 IgG seroprevalence (3.7%) compared to persons without HIV (7.4%), according to a retrospective matched case-control study (N=2,200) of remnant serum samples from US adults presenting for routine laboratory testing. However, among those who had past SARS-CoV-2 infection, persons living with HIV were more likely to have had severe&#8230;<\/p>\n<div><a class=\"more\" href=\"https:\/\/depts.washington.edu\/pandemicalliance\/2021\/04\/30\/sars-cov-2-seroprevalence-and-igg-concentration-and-pseudovirus-neutralising-antibody-titres-after-infection-compared-by-hiv-status-a-matched-case-control-observational-study\/\">Read more<\/a><\/div>\n","protected":false},"author":8,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":"","_links_to":"","_links_to_target":""},"categories":[6],"tags":[34],"topic":[20],"class_list":["post-9534","post","type-post","status-publish","format-standard","hentry","category-article-summary","tag-clinical-characteristics","topic-clinical-characteristics-and-health-care-setting"],"_links":{"self":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/9534","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/users\/8"}],"replies":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/comments?post=9534"}],"version-history":[{"count":1,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/9534\/revisions"}],"predecessor-version":[{"id":9535,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/9534\/revisions\/9535"}],"wp:attachment":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/media?parent=9534"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/categories?post=9534"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/tags?post=9534"},{"taxonomy":"topic","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/topic?post=9534"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}