{"id":9558,"date":"2021-05-03T14:12:48","date_gmt":"2021-05-03T21:12:48","guid":{"rendered":"https:\/\/depts.washington.edu\/pandemicalliance\/?p=9558"},"modified":"2021-05-06T14:13:51","modified_gmt":"2021-05-06T21:13:51","slug":"sars-cov-2-antibodies-remain-detectable-12-months-after-infection-and-antibody-magnitude-is-associated-with-age-and-covid-19-severity","status":"publish","type":"post","link":"https:\/\/depts.washington.edu\/pandemicalliance\/2021\/05\/03\/sars-cov-2-antibodies-remain-detectable-12-months-after-infection-and-antibody-magnitude-is-associated-with-age-and-covid-19-severity\/","title":{"rendered":"SARS-CoV-2 Antibodies Remain Detectable 12 Months after Infection and Antibody Magnitude Is Associated with Age and COVID-19 Severity"},"content":{"rendered":"<ul>\n<li style=\"font-weight: 400\"><i><span style=\"font-weight: 400\">[Pre-print, not peer-reviewed]<\/span><\/i><span style=\"font-weight: 400\"> An analysis of longitudinal serum samples collected from U.S. active <\/span><span style=\"font-weight: 400\">duty service members, dependents, and military retirees with PCR-confirmed SARS-CoV-2 infection between March 2020 and March 2021 found 100% seropositivity among inpatients followed for six months (58\/58) to one year (8\/8). Sero<\/span><span style=\"font-weight: 400\">re<\/span><span style=\"font-weight: 400\">version was observed in 5% (9\/192) of outpatients six to ten months after symptom onset, and 18% (2\/11) of outpatients followed for one year. In both groups, the half-life of anti-SARS-CoV-2 binding-IgG responses was &gt;1000 days post-symptom onset. Older age was positively correlated with both higher IgG binding and neutralizing antibody levels, after controlling for COVID-19 hospitalization status.\u00a0<\/span><\/li>\n<\/ul>\n<p><i><span style=\"font-weight: 400\">Laing et al.\u00a0(May 2, 2021). SARS-CoV-2 Antibodies Remain Detectable 12 Months after Infection and Antibody Magnitude Is Associated with Age and COVID-19 Severity. Pre-print downloaded May 3 from <\/span><\/i><a href=\"https:\/\/doi.org\/10.1101\/2021.04.27.21256207\"><span style=\"font-weight: 400\">https:\/\/doi.org\/10.1101\/2021.04.27.21256207<\/span><\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>[Pre-print, not peer-reviewed] An analysis of longitudinal serum samples collected from U.S. active duty service members, dependents, and military retirees with PCR-confirmed SARS-CoV-2 infection between March 2020 and March 2021 found 100% seropositivity among inpatients followed for six months (58\/58) to one year (8\/8). Seroreversion was observed in 5% (9\/192) of outpatients six to ten&#8230;<\/p>\n<div><a class=\"more\" href=\"https:\/\/depts.washington.edu\/pandemicalliance\/2021\/05\/03\/sars-cov-2-antibodies-remain-detectable-12-months-after-infection-and-antibody-magnitude-is-associated-with-age-and-covid-19-severity\/\">Read more<\/a><\/div>\n","protected":false},"author":8,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":"","_links_to":"","_links_to_target":""},"categories":[6],"tags":[201],"topic":[31],"class_list":["post-9558","post","type-post","status-publish","format-standard","hentry","category-article-summary","tag-immune-response","topic-vaccines-and-immunity"],"_links":{"self":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/9558","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/users\/8"}],"replies":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/comments?post=9558"}],"version-history":[{"count":1,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/9558\/revisions"}],"predecessor-version":[{"id":9559,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/9558\/revisions\/9559"}],"wp:attachment":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/media?parent=9558"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/categories?post=9558"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/tags?post=9558"},{"taxonomy":"topic","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/topic?post=9558"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}