{"id":9642,"date":"2021-05-06T17:03:22","date_gmt":"2021-05-07T00:03:22","guid":{"rendered":"https:\/\/depts.washington.edu\/pandemicalliance\/?p=9642"},"modified":"2021-05-07T17:04:04","modified_gmt":"2021-05-08T00:04:04","slug":"sars-cov-2-viral-load-kinetics-in-symptomatic-children-adolescents-and-adults","status":"publish","type":"post","link":"https:\/\/depts.washington.edu\/pandemicalliance\/2021\/05\/06\/sars-cov-2-viral-load-kinetics-in-symptomatic-children-adolescents-and-adults\/","title":{"rendered":"SARS-CoV-2 Viral Load Kinetics in Symptomatic Children, Adolescents and Adults"},"content":{"rendered":"<ul>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">Mean viral load (VL) was slightly lower at the time of SARS-CoV-2 infection diagnosis for children aged 0-13 years (6.2 log<\/span><span style=\"font-weight: 400\">10<\/span><span style=\"font-weight: 400\"> copies\/mL) and adolescents aged 14-19 years (6.4 log<\/span><span style=\"font-weight: 400\">10<\/span><span style=\"font-weight: 400\"> copies\/mL) compared to adults aged\u00a0 \u226520 years (6.7 log<\/span><span style=\"font-weight: 400\">10<\/span><span style=\"font-weight: 400\"> copies\/mL) in a study in Switzerland (n=8,027). At time of diagnosis, the proportion of adults with VL &gt; 6 log<\/span><span style=\"font-weight: 400\">10<\/span><span style=\"font-weight: 400\"> copies\/mL (defined threshold for infectious virus) was significantly higher when compared to children (69% vs 58%). Analysis of VL kinetics, using day of symptom onset as an anchor, show that VL peaked within 3 days post symptom onset, with VL in children peaking and declining slightly faster compared to adults. All groups presented with VL &gt; 6 log<\/span><span style=\"font-weight: 400\">10<\/span><span style=\"font-weight: 400\"> copies\/mL up to 5 days post symptom onset.<\/span><\/li>\n<\/ul>\n<p><i><span style=\"font-weight: 400\">Bellon et al.\u00a0(May 5, 2021). SARS-CoV-2 Viral Load Kinetics in Symptomatic Children, Adolescents and Adults. Clinical Infectious Diseases. <\/span><\/i><a href=\"https:\/\/doi.org\/10.1093\/cid\/ciab396\"><span style=\"font-weight: 400\">https:\/\/doi.org\/10.1093\/cid\/ciab396<\/span><\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Mean viral load (VL) was slightly lower at the time of SARS-CoV-2 infection diagnosis for children aged 0-13 years (6.2 log10 copies\/mL) and adolescents aged 14-19 years (6.4 log10 copies\/mL) compared to adults aged\u00a0 \u226520 years (6.7 log10 copies\/mL) in a study in Switzerland (n=8,027). At time of diagnosis, the proportion of adults with VL&#8230;<\/p>\n<div><a class=\"more\" href=\"https:\/\/depts.washington.edu\/pandemicalliance\/2021\/05\/06\/sars-cov-2-viral-load-kinetics-in-symptomatic-children-adolescents-and-adults\/\">Read more<\/a><\/div>\n","protected":false},"author":8,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":"","_links_to":"","_links_to_target":""},"categories":[6],"tags":[41,34],"topic":[20],"class_list":["post-9642","post","type-post","status-publish","format-standard","hentry","category-article-summary","tag-children","tag-clinical-characteristics","topic-clinical-characteristics-and-health-care-setting"],"_links":{"self":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/9642","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/users\/8"}],"replies":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/comments?post=9642"}],"version-history":[{"count":1,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/9642\/revisions"}],"predecessor-version":[{"id":9643,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/9642\/revisions\/9643"}],"wp:attachment":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/media?parent=9642"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/categories?post=9642"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/tags?post=9642"},{"taxonomy":"topic","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/topic?post=9642"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}