{"id":9658,"date":"2021-05-07T15:06:13","date_gmt":"2021-05-07T22:06:13","guid":{"rendered":"https:\/\/depts.washington.edu\/pandemicalliance\/?p=9658"},"modified":"2021-05-12T15:07:04","modified_gmt":"2021-05-12T22:07:04","slug":"antibody-response-to-mrna-sars-cov-2-vaccine-among-kidney-transplant-recipients-prospective-cohort-study","status":"publish","type":"post","link":"https:\/\/depts.washington.edu\/pandemicalliance\/2021\/05\/07\/antibody-response-to-mrna-sars-cov-2-vaccine-among-kidney-transplant-recipients-prospective-cohort-study\/","title":{"rendered":"Antibody Response to MRNA SARS-CoV-2 Vaccine among Kidney\u00a0 Transplant Recipients \u2013 Prospective Cohort Study"},"content":{"rendered":"<ul>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">A study of kidney transplant recipients who received the Pfizer-BioNTech vaccine (N=308) found that\u00a0 only 36% tested positive for anti-SARS-CoV-2 antibodies 2-4 weeks after receiving the second dose.\u00a0 Factors associated with antibody detection included younger age, higher renal function, and\u00a0 reduced immunosuppression. The authors note that although correlation between antibody levels\u00a0 and protection has not been proven, detection of antibodies is much higher in non immunocompromised persons after receipt of the vaccine. These results may indicate a need for\u00a0 additional booster doses, modified vaccine dosing, or mixing vaccine types to improve immune\u00a0 response to vaccinations in transplant recipients.\u00a0<\/span><\/li>\n<\/ul>\n<p><i><span style=\"font-weight: 400\">Rozen-Zvi et al. (May 2021). Antibody Response to MRNA SARS-CoV-2 Vaccine among Kidney\u00a0 Transplant Recipients \u2013 Prospective Cohort Study. Clinical Microbiology and Infection.\u00a0 <\/span><\/i><a href=\"https:\/\/doi.org\/10.1016\/j.cmi.2021.04.028\"><span style=\"font-weight: 400\">https:\/\/doi.org\/10.1016\/j.cmi.2021.04.028<\/span><span style=\"font-weight: 400\">\u00a0<\/span><\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>A study of kidney transplant recipients who received the Pfizer-BioNTech vaccine (N=308) found that\u00a0 only 36% tested positive for anti-SARS-CoV-2 antibodies 2-4 weeks after receiving the second dose.\u00a0 Factors associated with antibody detection included younger age, higher renal function, and\u00a0 reduced immunosuppression. The authors note that although correlation between antibody levels\u00a0 and protection has not&#8230;<\/p>\n<div><a class=\"more\" href=\"https:\/\/depts.washington.edu\/pandemicalliance\/2021\/05\/07\/antibody-response-to-mrna-sars-cov-2-vaccine-among-kidney-transplant-recipients-prospective-cohort-study\/\">Read more<\/a><\/div>\n","protected":false},"author":8,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":"","_links_to":"","_links_to_target":""},"categories":[6],"tags":[32,142],"topic":[31],"class_list":["post-9658","post","type-post","status-publish","format-standard","hentry","category-article-summary","tag-immunity","tag-vaccine","topic-vaccines-and-immunity"],"_links":{"self":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/9658","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/users\/8"}],"replies":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/comments?post=9658"}],"version-history":[{"count":1,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/9658\/revisions"}],"predecessor-version":[{"id":9659,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/9658\/revisions\/9659"}],"wp:attachment":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/media?parent=9658"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/categories?post=9658"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/tags?post=9658"},{"taxonomy":"topic","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/topic?post=9658"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}