{"id":9832,"date":"2021-05-17T10:11:15","date_gmt":"2021-05-17T17:11:15","guid":{"rendered":"https:\/\/depts.washington.edu\/pandemicalliance\/?p=9832"},"modified":"2021-05-18T10:11:52","modified_gmt":"2021-05-18T17:11:52","slug":"anti-sars-cov-2-antibodies-persist-for-up-to-13-months-and-reduce-risk-of-reinfection","status":"publish","type":"post","link":"https:\/\/depts.washington.edu\/pandemicalliance\/2021\/05\/17\/anti-sars-cov-2-antibodies-persist-for-up-to-13-months-and-reduce-risk-of-reinfection\/","title":{"rendered":"Anti-SARS-CoV-2 Antibodies Persist for up to 13 Months and Reduce Risk of Reinfection"},"content":{"rendered":"<ul>\n<li style=\"font-weight: 400\"><i><span style=\"font-weight: 400\">[Pre-print, not peer-reviewed]<\/span><\/i><span style=\"font-weight: 400\"> A longitudinal study of antibody responses among healthcare workers in France, 916 of whom had not had COVID-19 and 393 who were convalescent, found that almost all convalescent individuals (96%) had persistence of anti-S IgG antibodies one year after infection. From month 1 until months 7-9 after infection, <\/span><span style=\"font-weight: 400\">SARS-CoV-2 antibodies decreased, with men showing a slower decay of anti-N and a faster decay of anti-S antibodies than women. By months 11-13, anti-N decreased while anti-S stabilized. 69 individuals who were SARS-CoV-2 negative at baseline eventually tested positive, (incidence of 12.22 per 100 person-years) versus one with prior infection (0.40 per 100 person-years), for a relative reduction in the incidence of SARS-CoV-2 reinfection of 96.7%. After vaccination, anti-S antibodies significantly increased to levels found to neutralize the <\/span><span style=\"font-weight: 400\">D614G, B.1.1.7, and B.1.351 variants in the subset of isolates tested, with antibody level independent of <\/span><span style=\"font-weight: 400\">pre-vaccination IgG levels, type of vaccine, and number of doses.\u00a0<\/span><\/li>\n<\/ul>\n<p><i><span style=\"font-weight: 400\">Gallais et al.\u00a0(May 14, 2021). Anti-SARS-CoV-2 Antibodies Persist for up to 13 Months and Reduce Risk of Reinfection. Pre-print downloaded May 17 from <\/span><\/i><a href=\"https:\/\/doi.org\/10.1101\/2021.05.07.21256823\"><span style=\"font-weight: 400\">https:\/\/doi.org\/10.1101\/2021.05.07.21256823<\/span><\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>[Pre-print, not peer-reviewed] A longitudinal study of antibody responses among healthcare workers in France, 916 of whom had not had COVID-19 and 393 who were convalescent, found that almost all convalescent individuals (96%) had persistence of anti-S IgG antibodies one year after infection. From month 1 until months 7-9 after infection, SARS-CoV-2 antibodies decreased, with&#8230;<\/p>\n<div><a class=\"more\" href=\"https:\/\/depts.washington.edu\/pandemicalliance\/2021\/05\/17\/anti-sars-cov-2-antibodies-persist-for-up-to-13-months-and-reduce-risk-of-reinfection\/\">Read more<\/a><\/div>\n","protected":false},"author":8,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":"","_links_to":"","_links_to_target":""},"categories":[6],"tags":[32,159],"topic":[31],"class_list":["post-9832","post","type-post","status-publish","format-standard","hentry","category-article-summary","tag-immunity","tag-variants","topic-vaccines-and-immunity"],"_links":{"self":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/9832","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/users\/8"}],"replies":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/comments?post=9832"}],"version-history":[{"count":1,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/9832\/revisions"}],"predecessor-version":[{"id":9833,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/9832\/revisions\/9833"}],"wp:attachment":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/media?parent=9832"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/categories?post=9832"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/tags?post=9832"},{"taxonomy":"topic","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/topic?post=9832"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}