{"id":9877,"date":"2021-05-18T10:29:27","date_gmt":"2021-05-18T17:29:27","guid":{"rendered":"https:\/\/depts.washington.edu\/pandemicalliance\/?p=9877"},"modified":"2021-05-19T10:30:09","modified_gmt":"2021-05-19T17:30:09","slug":"extended-interval-bnt162b2-vaccination-enhances-peak-antibody-generation-in-older-people","status":"publish","type":"post","link":"https:\/\/depts.washington.edu\/pandemicalliance\/2021\/05\/18\/extended-interval-bnt162b2-vaccination-enhances-peak-antibody-generation-in-older-people\/","title":{"rendered":"Extended Interval BNT162b2 Vaccination Enhances Peak Antibody Generation in Older People"},"content":{"rendered":"<ul>\n<li style=\"font-weight: 400\"><i><span style=\"font-weight: 400\">[Pre-print, not peer-reviewed]<\/span><\/i><span style=\"font-weight: 400\"> Adults aged &gt;80 years with 11-12 week intervals between doses of the Pfizer-BioNTech vaccine (n=79) had 3.5-fold higher peak titers of anti-SARS-CoV-2 spike antibodies compared to adults &gt;80 given a standard three-week interval between doses (n=68) in a cohort study of in the UK. However, the magnitude of spike-specific T cell responses 2-3 weeks after the second dose was 3.6-fold lower in the extended interval cohort compared to the standard interval cohort.<\/span><\/li>\n<\/ul>\n<p><i><span style=\"font-weight: 400\">Parry et al.\u00a0(May 17, 2021). Extended Interval BNT162b2 Vaccination Enhances Peak Antibody Generation in Older People. Pre-print downloaded May 18 from <\/span><\/i><a href=\"https:\/\/doi.org\/10.1101\/2021.05.15.21257017\"><span style=\"font-weight: 400\">https:\/\/doi.org\/10.1101\/2021.05.15.21257017<\/span><\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>[Pre-print, not peer-reviewed] Adults aged &gt;80 years with 11-12 week intervals between doses of the Pfizer-BioNTech vaccine (n=79) had 3.5-fold higher peak titers of anti-SARS-CoV-2 spike antibodies compared to adults &gt;80 given a standard three-week interval between doses (n=68) in a cohort study of in the UK. However, the magnitude of spike-specific T cell responses&#8230;<\/p>\n<div><a class=\"more\" href=\"https:\/\/depts.washington.edu\/pandemicalliance\/2021\/05\/18\/extended-interval-bnt162b2-vaccination-enhances-peak-antibody-generation-in-older-people\/\">Read more<\/a><\/div>\n","protected":false},"author":8,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":"","_links_to":"","_links_to_target":""},"categories":[6],"tags":[33],"topic":[31],"class_list":["post-9877","post","type-post","status-publish","format-standard","hentry","category-article-summary","tag-vaccines","topic-vaccines-and-immunity"],"_links":{"self":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/9877","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/users\/8"}],"replies":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/comments?post=9877"}],"version-history":[{"count":1,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/9877\/revisions"}],"predecessor-version":[{"id":9878,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/9877\/revisions\/9878"}],"wp:attachment":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/media?parent=9877"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/categories?post=9877"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/tags?post=9877"},{"taxonomy":"topic","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/topic?post=9877"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}