Case List History Objectives Radiology Images Questions SURGICAL ENDOCRINOLOGY Case #4 - A 60 year old with hypercalcemia DISCUSSION QUESTIONS: 4.) What are the various regulators of calcium metabolism in the body and how do they work? Regulators of the body's calcium metabolism: Parathyroid Hormone (PTH): stimulates reabsorption of calcium from bone calcium reabsorption, promotes renal phosphate clearance, promotes 1,25 Vitamin D synthesis Calcitonin: decreases reabsorption of calcium from bone Vitamin D: promotes GI absorption of calcium Calcitriol (formed in the kidney on stimulation by PTH): promotes calcium absorption from the GI tract
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