Case List History Objectives Radiology Images Questions COLORECTAL DISEASE Case #8 - A 55 year old male with 3 months rectal bleeding DISCUSSION QUESTIONS: 12.) When should the patient receive neoadjuvant therapy? Adjuvant therapy? All Stages II, III, and IV rectal carcinomas should receive neoadjuvant chemoradiation to downsize the tumor, which facilitates the ability to perform a low anterior resection, and decreases the risk of local recurrence. The disadvantages of this approach are that pathologic staging is not accurate and the radiation may adversely affect wound healing. Stage I lesions do not require neoadjuvant or adjuvant therapy.
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