Case List History Objectives Radiology Images Questions BREAST DISEASE Case #6 - 50 year old female with thickening in the right breast DISCUSSION QUESTIONS: 5.) What is the significance of lobular carcinoma in situ when seen in a breast biopsy? Lobular carcinoma in situ, when found in a biopsy, is an indicator of increased risk for both invasive duct cell carcinoma and invasive lobular carcinoma. Lobular carcinoma in situ may also be a precursor for invasive lobular carcinoma. The risk of having invasive lobular carcinoma is greater in the presence of lobular carcinoma in situ than in the absence of LCIS.
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